Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene

Oncology Reports

Volumn 10, Issue 4, 2003, Pages 859-866

  Yamada, Kanae ^a   Zhong, Xiaoling ^a   Kanazawa, Shinsaku ^a   Koike, Junichi ^a   Tsujita, Kazunori ^a   Hemmi, Hiromichi ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Colorectal cancer; Germline missense mutation; hMSH2 gene; Microsatellite instability

Indexed keywords

DNA; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MICROSATELLITE DNA; MSH2 PROTEIN, HUMAN; MSH3 PROTEIN, HUMAN; ONCOPROTEIN; PRIMER DNA; PROTEIN MSH2;

AMINO ACID SEQUENCE; ARTICLE; BASE MISPAIRING; CASE CONTROL STUDY; CHEMISTRY; COLORECTAL TUMOR; COMPARATIVE STUDY; GENETICS; HETEROZYGOSITY LOSS; HUMAN; MISSENSE MUTATION; MOLECULAR GENETICS; MUTATION; ONCOGENE RAS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; BASE PAIR MISMATCH; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DNA PRIMERS; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENES, P53; GENES, RAS; GERM-LINE MUTATION; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; MUTS HOMOLOG 2 PROTEIN; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0344456117     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.4.859     Document Type: Article

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