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Volumn 9, Issue 12, 2003, Pages 1491-1501

A role for the exosome in the in vivo degradation of unstable mRNAs

Author keywords

Degradation; Exosome; mRNA; Trypanosoma; Turnover

Indexed keywords

EXONUCLEASE; EXOSOME COMPLEX; MESSENGER RNA; PROTEIN; PROTEIN CSL4; PROTEIN RRP4; PROTEIN RRP45; UNCLASSIFIED DRUG;

EID: 0344442427     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5940703     Document Type: Article
Times cited : (62)

References (39)
  • 3
    • 0029053016 scopus 로고
    • Degradation of mRNA in eukaryotes
    • Beelman, C.A. and Parker, R. 1995. Degradation of mRNA in eukaryotes. Cell 81: 179-184.
    • (1995) Cell , vol.81 , pp. 179-184
    • Beelman, C.A.1    Parker, R.2
  • 4
    • 0343907190 scopus 로고    scopus 로고
    • Vectors for inducible over-expression of potentially toxic gene products in blood-stream and procyclic Trypanosoma brucei
    • Biebinger, S., Wirtz, L.E., and Clayton, C.E. 1997. Vectors for inducible over-expression of potentially toxic gene products in blood-stream and procyclic Trypanosoma brucei. Mol. Biochem. Parasitol. 85: 99-112.
    • (1997) Mol. Biochem. Parasitol. , vol.85 , pp. 99-112
    • Biebinger, S.1    Wirtz, L.E.2    Clayton, C.E.3
  • 5
    • 0034653560 scopus 로고    scopus 로고
    • Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability
    • Carballo, E., Lai, W.S., and Blackshear, P.J. 2000. Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood 95: 1891-1899.
    • (2000) Blood , vol.95 , pp. 1891-1899
    • Carballo, E.1    Lai, W.S.2    Blackshear, P.J.3
  • 6
    • 0028788194 scopus 로고
    • AU-rich elements: Characterization and importance in mRNA degradation
    • Chen, C.Y. and Shyu, A.B. 1995. AU-rich elements: Characterization and importance in mRNA degradation. Trends. Biochem. Sci. 20: 465-470.
    • (1995) Trends. Biochem. Sci. , vol.20 , pp. 465-470
    • Chen, C.Y.1    Shyu, A.B.2
  • 8
    • 0037090528 scopus 로고    scopus 로고
    • Developmental regulation without transcriptional control? From fly to man and back again
    • Clayton, C.E. 2002. Developmental regulation without transcriptional control? From fly to man and back again. EMBO J. 21: 1881-1888.
    • (2002) EMBO J. , vol.21 , pp. 1881-1888
    • Clayton, C.E.1
  • 9
    • 0032778820 scopus 로고    scopus 로고
    • Structure of a regulatory 3′-untranslated region from Trypanosoma brucei
    • Drozdz, M. and Clayton, C.E. 1999 Structure of a regulatory 3′-untranslated region from Trypanosoma brucei. RNA 5: 1632-1644.
    • (1999) RNA , vol.5 , pp. 1632-1644
    • Drozdz, M.1    Clayton, C.E.2
  • 10
    • 0035898660 scopus 로고    scopus 로고
    • The exosome of Trypanosoma brucei
    • Estévez, A., Kempf, T., and Clayton, C.E. 2001. The exosome of Trypanosoma brucei. EMBO J. 20: 3831-3839.
    • (2001) EMBO J. , vol.20 , pp. 3831-3839
    • Estévez, A.1    Kempf, T.2    Clayton, C.E.3
  • 12
    • 0033555659 scopus 로고    scopus 로고
    • ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system
    • Ford, L.P., Watson, J., Keene, J.D., and Wilusz, J. 1999. ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes & Dev. 13: 188-201.
    • (1999) Genes & Dev. , vol.13 , pp. 188-201
    • Ford, L.P.1    Watson, J.2    Keene, J.D.3    Wilusz, J.4
  • 13
    • 0036629337 scopus 로고    scopus 로고
    • Compartmentation of enzymes in a microbody, the glycosome, is essential in Trypanosoma brucei
    • Guerra-Giraldez, C., Quijada, L., and Clayton, C.E. 2002. Compartmentation of enzymes in a microbody, the glycosome, is essential in Trypanosoma brucei. J. Cell Sci. 115: 2651-2658.
    • (2002) J. Cell Sci. , vol.115 , pp. 2651-2658
    • Guerra-Giraldez, C.1    Quijada, L.2    Clayton, C.E.3
  • 14
    • 0035397515 scopus 로고    scopus 로고
    • The roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei
    • Helfert, S., Estévez, A., Bakker, B., Michels, P., and Clayton, C.E. 2001. The roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei. Biochem. J. 357: 55-61.
    • (2001) Biochem. J. , vol.357 , pp. 55-61
    • Helfert, S.1    Estévez, A.2    Bakker, B.3    Michels, P.4    Clayton, C.E.5
  • 15
    • 0035807308 scopus 로고    scopus 로고
    • Quality control of mRNA 3′-end processing is linked to the nuclear exosome
    • Hilleren, P., McCarthy, T., Rosbash, M., Parker, R., and Jensen, T.H. 2001. Quality control of mRNA 3′-end processing is linked to the nuclear exosome. Nature 413: 538-542.
    • (2001) Nature , vol.413 , pp. 538-542
    • Hilleren, P.1    McCarthy, T.2    Rosbash, M.3    Parker, R.4    Jensen, T.H.5
  • 16
    • 0030859962 scopus 로고    scopus 로고
    • Mechanisms of developmental regulation in Trypanosoma brucei: A polypyrimidine tract in the 3′-untranslated region of a trypanosome surface protein mRNA affects RNA abundance and translation
    • Hotz, H.-R., Hartmann, C., Huober, K., Hug, M., and Clayton, C.E. 1997. Mechanisms of developmental regulation in Trypanosoma brucei: A polypyrimidine tract in the 3′-untranslated region of a trypanosome surface protein mRNA affects RNA abundance and translation. Nucleic Acids Res. 25: 3017-3025.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3017-3025
    • Hotz, H.-R.1    Hartmann, C.2    Huober, K.3    Hug, M.4    Clayton, C.E.5
  • 17
    • 0027973039 scopus 로고
    • Hierarchies of RNA processing signals in a trypanosome surface antigen mRNA precursor
    • Hug, M., Hotz, H.R., Hartmann, C., and Clayton, C.E. 1994. Hierarchies of RNA processing signals in a trypanosome surface antigen mRNA precursor. Mol. Cell. Biol. 14: 7428-7435.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7428-7435
    • Hug, M.1    Hotz, H.R.2    Hartmann, C.3    Clayton, C.E.4
  • 18
    • 0035890839 scopus 로고    scopus 로고
    • Degradation of the EP1 mRNA in Trypanosoma brucei is initiated by destruction of the 3′-untranslated region
    • Irmer, H. and Clayton, C.E. 2001. Degradation of the EP1 mRNA in Trypanosoma brucei is initiated by destruction of the 3′-untranslated region. Nucleic Acids Res. 29: 4707-4715.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4707-4715
    • Irmer, H.1    Clayton, C.E.2
  • 19
    • 0000577868 scopus 로고    scopus 로고
    • The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex
    • Jacobs, J.S., Anderson, A.R., and Parker, R.P. 1998. The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex. EMBO J. 17: 1497-1506.
    • (1998) EMBO J. , vol.17 , pp. 1497-1506
    • Jacobs, J.S.1    Anderson, A.R.2    Parker, R.P.3
  • 20
    • 0035912793 scopus 로고    scopus 로고
    • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome
    • Keene, J.D. 2001. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. Proc. Natl. Acad. Sci. 98: 7018-7024.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 7018-7024
    • Keene, J.D.1
  • 21
    • 0030856470 scopus 로고    scopus 로고
    • Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex
    • Kiledjian, M., DeMaria, C.T., Brewer, G., and Novick, K. 1997. Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex. Mol. Cell Biol. 17: 4870-4876.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 4870-4876
    • Kiledjian, M.1    DeMaria, C.T.2    Brewer, G.3    Novick, K.4
  • 22
    • 0033049125 scopus 로고    scopus 로고
    • Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
    • Lai, W.S., Carballo, E., Strum, J.R., Kennington, E.A., Phillips, R.S., and Blackshear, P.J. 1999. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol. Cell Biol. 19: 4311-4323.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 4311-4323
    • Lai, W.S.1    Carballo, E.2    Strum, J.R.3    Kennington, E.A.4    Phillips, R.S.5    Blackshear, P.J.6
  • 23
    • 0033565383 scopus 로고    scopus 로고
    • Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element
    • Loflin, P.A., Chen, C.-Y.A., and Shyu, A.-B. 1999. Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element. Genes & Dev. 13: 1884-1897.
    • (1999) Genes & Dev. , vol.13 , pp. 1884-1897
    • Loflin, P.A.1    Chen, C.-Y.A.2    Shyu, A.-B.3
  • 24
    • 0034816062 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
    • Mahtani, K.R., Brook, M., Dean, J.L.E., Sully, G., Saklatvala, J., and Clark, A.R. 2001. Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol. Cell. Biol. 21: 6461-6469.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6461-6469
    • Mahtani, K.R.1    Brook, M.2    Dean, J.L.E.3    Sully, G.4    Saklatvala, J.5    Clark, A.R.6
  • 25
    • 0037106465 scopus 로고    scopus 로고
    • Identification of mRNA decapping activities and an ARE-regulated 3′ to 5′ exonuclease activity in trypanosome extracts
    • Milone, J., Wilusz, J., and Bellofatto, V. 2002. Identification of mRNA decapping activities and an ARE-regulated 3′ to 5′ exonuclease activity in trypanosome extracts. Nucleic Acids Res. 30: 4040-4050.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4040-4050
    • Milone, J.1    Wilusz, J.2    Bellofatto, V.3
  • 27
    • 0035371050 scopus 로고    scopus 로고
    • mRNA turnover
    • -. 2001. mRNA turnover. Curr. Opin. Cell Biol. 13: 320-325.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 320-325
  • 28
    • 0037080834 scopus 로고    scopus 로고
    • The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements
    • Mukherjee, D., Gao, M., O'Connor, J.P., Raijmakers, R., Pruijn, G., Lutz, C.S., and Wilusz, J. 2002. The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J. 21: 165-174.
    • (2002) EMBO J. , vol.21 , pp. 165-174
    • Mukherjee, D.1    Gao, M.2    O'Connor, J.P.3    Raijmakers, R.4    Pruijn, G.5    Lutz, C.S.6    Wilusz, J.7
  • 29
    • 0345152050 scopus 로고    scopus 로고
    • Expression of the human RNA-binding protein HuR in Trypanosoma brucei induces differentiation-related changes in the abundance of developmentally regulated mRNAs
    • Quijada, L., Hartmann, C., Guerra-Giraldez, C., Drozdz, M., Irmer, H., and Clayton, C.E. 2002. Expression of the human RNA-binding protein HuR in Trypanosoma brucei induces differentiation-related changes in the abundance of developmentally regulated mRNAs. Nucleic Acids Res. 30: 1-11.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1-11
    • Quijada, L.1    Hartmann, C.2    Guerra-Giraldez, C.3    Drozdz, M.4    Irmer, H.5    Clayton, C.E.6
  • 30
    • 0036977391 scopus 로고    scopus 로고
    • Protein-Protein Interactions between Human Exosome Components Support the Assembly of RNase PH-type Subunits into a Six-membered PNPase-like Ring
    • Raijmakers, R., Ebgerts, W.V., van Venrooij, W.J., and Pruijn, G.J.M. 2002. Protein-Protein Interactions between Human Exosome Components Support the Assembly of RNase PH-type Subunits into a Six-membered PNPase-like Ring. J. Mol. Biol. 323: 653-663.
    • (2002) J. Mol. Biol. , vol.323 , pp. 653-663
    • Raijmakers, R.1    Ebgerts, W.V.2    Van Venrooij, W.J.3    Pruijn, G.J.M.4
  • 31
    • 0038996729 scopus 로고    scopus 로고
    • Contribution of the procyclin 3′ untranslated region and coding region to the regulation of expression in bloodstream forms of Trypanosoma brucei
    • Schürch, N., Furger, A., Kurath, U., and Roditi, I. 1997. Contribution of the procyclin 3′ untranslated region and coding region to the regulation of expression in bloodstream forms of Trypanosoma brucei. Mol. Biochem. Parasit. 89: 109-121.
    • (1997) Mol. Biochem. Parasit. , vol.89 , pp. 109-121
    • Schürch, N.1    Furger, A.2    Kurath, U.3    Roditi, I.4
  • 32
    • 0037968357 scopus 로고    scopus 로고
    • Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
    • Sheth, U. and Parker, R. 2003. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300: 805-808.
    • (2003) Science , vol.300 , pp. 805-808
    • Sheth, U.1    Parker, R.2
  • 33
    • 0035983990 scopus 로고    scopus 로고
    • Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs
    • Torchet, C., Bousquet-Antonelli, C., Milligan, L., Thompson, E., Kufel, J., and Tollervey, D. 2002. Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs. Mol. Cell 9: 1285-1296.
    • (2002) Mol. Cell , vol.9 , pp. 1285-1296
    • Torchet, C.1    Bousquet-Antonelli, C.2    Milligan, L.3    Thompson, E.4    Kufel, J.5    Tollervey, D.6
  • 35
    • 0037117760 scopus 로고    scopus 로고
    • Messenger RNA degradation: Beginning at the end
    • van Hoof, A. and Parker, R. 2002. Messenger RNA degradation: Beginning at the end. Curr. Biol. 12: R285-R287.
    • (2002) Curr. Biol. , vol.12
    • Van Hoof, A.1    Parker, R.2
  • 36
    • 0033981301 scopus 로고    scopus 로고
    • Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs
    • van Hoof, A., Lennertz, P., and Parker, R. 2000. Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol. Cell. Biol. 20: 441-452.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 441-452
    • Van Hoof, A.1    Lennertz, P.2    Parker, R.3
  • 37
    • 0035861864 scopus 로고    scopus 로고
    • Functional link between the mammalian exosome and mRNA decapping
    • Wang, Z. and Kiledjian, M. 2001. Functional link between the mammalian exosome and mRNA decapping. Cell 107: 751-762.
    • (2001) Cell , vol.107 , pp. 751-762
    • Wang, Z.1    Kiledjian, M.2
  • 38
    • 0034908634 scopus 로고    scopus 로고
    • Loss of HuR is linked to reduced expression of proliferate genes during replicative senescense
    • Wang, W., Yang, X., Cristofalo, V.J., Holbrook, N.J., and Gorospe, M. 2001. Loss of HuR is linked to reduced expression of proliferate genes during replicative senescense. Mol. Cell. Biol. 21: 5889-5898.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5889-5898
    • Wang, W.1    Yang, X.2    Cristofalo, V.J.3    Holbrook, N.J.4    Gorospe, M.5
  • 39
    • 0033105059 scopus 로고    scopus 로고
    • The exosome subunit Rrp43p is required for the efficient maturation of 5.8S, 18S and 25S rRNA
    • Zanchin, N.I. and Goldfarb, D.S. 1999. The exosome subunit Rrp43p is required for the efficient maturation of 5.8S, 18S and 25S rRNA. Nucleic Acids Res. 27: 1283-1288.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1283-1288
    • Zanchin, N.I.1    Goldfarb, D.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.