Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation

Journal of Medicinal Chemistry

Volumn 42, Issue 19, 1999, Pages 3800-3808

  Gibbs, Barbara S ^a   Zahn, Todd J ^b   Mu, YongQi ^b,c   Sebolt Leopold, Judith S ^a   Gibbs, Richard A ^b  

^a PFIZER INC   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c Advanced Medicine Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 ALLYLFARNESOL; 3 ALLYLGERANYLGERANIOL; 3 ETHYLFARNESOL; 3 PHENYLFARNESOL; 3 VINYLFARNESOL; 3 VINYLGERANYLGERANIOL; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER THERAPY; DRUG POTENCY; ENZYME INHIBITION; PRENYLATION;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; CATALYSIS; DITERPENES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FARNESOL; KINETICS; MODELS, CHEMICAL; PROTEIN ISOPRENYLATION; TUMOR CELLS, CULTURED;

EID: 0033598364     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9902786     Document Type: Article

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