Genetic bottlenecks, perceived racism, and hypertension risk among African Americans and first-generation African immigrants

Journal of Human Hypertension

Volumn 15, Issue 5, 2001, Pages 341-351

  Carlos Poston, Walker S ^a   Pavlik, V N ^b   Hyman, D J ^b   Ogbonnaya, K ^b   Hanis, C L ^b   Haddock, C K ^b   Hyder, M L ^b   Foreyt, J P ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b University of Missouri Kansas City ^*

Author keywords

African Americans; First generation African immigrants; G proteins; Genetics

Indexed keywords

ANGIOTENSINOGEN; DIPEPTIDYL CARBOXYPEPTIDASE; GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; AFRICA; AGE; ALLELE; ARTICLE; BODY MASS; CULTURAL FACTOR; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HEALTH CARE PERSONNEL; HEALTH SURVEY; HOMOZYGOSITY; HUMAN; HYPERTENSION; IMMIGRANT; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; PREDICTION; RACE DIFFERENCE; RISK FACTOR; SOCIAL PSYCHOLOGY; UNITED STATES;

ADULT; AFRICA; AFRICAN AMERICANS; AFRICAN CONTINENTAL ANCESTRY GROUP; ANALYSIS OF VARIANCE; ANGIOTENSINOGEN; ANTHROPOMETRY; BLOOD GLUCOSE; BODY MASS INDEX; CHI-SQUARE DISTRIBUTION; CROSS-OVER STUDIES; EMIGRATION AND IMMIGRATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GTP-BINDING PROTEINS; HEALTH SURVEYS; HUMANS; HYPERTENSION; LIFE STYLE; LOGISTIC MODELS; MALE; MIDDLE AGED; PEDIGREE; PEPTIDYL-DIPEPTIDASE A; PREJUDICE; RISK ASSESSMENT; RISK FACTORS; SAMPLING STUDIES; UNITED STATES;

EID: 0343833342     PISSN: 09509240     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jhh.1001174     Document Type: Article

References (71)

1. Geronimus AT et al. Excess mortality among blacks and whites in the United States. N Engl J Med 1996; 335: 1552-1558.
2. Gillum RF. The epidemiology of cardiovascular disease in Black Americans. N Engl J Med 1996; 335: 1597-1599.
3. Cooper R, Rotimi C. Hypertension in blacks. Am J Hypertens 1997; 10: 804-812.
4. Burt VL et al. Prevalence of hypertension in the U.S. adult population: results from the Third National Health Examination and Nutrition Surveys, 1988-1991. Hypertension 1995; 25: 305-313.
5. Adorgué HJ, Wesson DJ. Role of dietary factors in the hypertension of African Americans. Semin Nephrol 1996; 16: 94-101.
6. Kaplan NM. Ethnic aspects of hypertension. Lancet 1994; 344: 450-452.
7. Kaplan NM. Clinical Hypertension (7th Edition). Williams & Wilkins: Baltimore, MD, 1998.
8. Winkleby MA, Kraemer HC, Ahn DK, Varady AN. Ethnic and socioeconomic differences in cardiovascular disease risk factors: findings for women from the Third National Health and Nutrition Examination Survey, 1988-1994. JAMA 1988; 280: 356-362.
9. Blaustein MP, Grim CE. The pathogenesis of hypertension: black-white differences. In: Saunders E (ed). Cardiovascular Disesases in Blacks. F.A. Davis Company. Philadelphia, PA, 1997, pp 97-114.
10. Grim CE, Robinson M. Blood pressure variation in blacks: genetic factors. Semin Nephrol 1996; 16: 83-83.
11. Wilson TW, Grim CE. Biohistory of slavery and blood pressure differences in blacks today. Hypertension 1991; 17 (Suppl I): I-122-I-128.
12. Jackson FL. An evolutionary perspective on salt, hypertension, and human genetic vulnerability. Hypertension 1991; 17 (Suppl 1): I129-I132.
13. Asamoah A et al. A deletion in the angiotonsin converting enzyme (ACE) gene is common among African Americans with essential hypertension. Clin Chim Acta 1996; 254: 41-46.
14. Barley J et al. Angiotensin converting enzyme insertion/deletion polymorphism: association with ethnic origin. J Hypertens 1994; 12: 955-957.
15. Borecki IB et al. Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI Family Heart Study. Ann Epidemiol 1997; 7: 13-21.
16. Brand E et al. Evaluation of the angiotensinogen locus in human hypertension: a European study. Hypertension 1998; 31: 725-729.
17. Caulfield M et al. Linkage of the angiotensiongen gene to essential hypertension. N Engl J Med 1994; 330: 1629-1633.
18. Caulfield M et al. Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. J Clin Invest 1995; 96: 687-692.
19. Caulfield M et al. Angiotensinogen in human essential hypertension. Hypertension 1996; 28: 1123-1125.
20. Duru K et al. Frequency of a deletion polymorphism in the gene for angiotensin converting enzyme is increased in African-Americans with hypertension. Am J Hypertens 1994; 7: 759-762.
21. Fornage M et al. Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. Circulation 1998; 97: 1773-1779.
22. Forrester T et al. Angiotensinogen and blood pressure among blacks: findings from a community survey in Jamaica. J Hypertens 1996; 14: 315-321.
23. Jeunemaitre X et al. Halotypes of angiotensinogen in essential hypertension. Am J Hum Genet 1997; 60: 1448-1460.
24. O'Donnell CJ et al. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation 1998; 97: 1766-1772.
25. Rutledge DR, Browe CS, Kubilis PS, Ross EA. Analysis of two variants of the angiotensinogen gene in essential hypertensive African-Americans. Am J Hypertens 1994; 7: 651-654.
26. Rutledge DR, Browe CS, Ross EA. Frequencies of the angiotensinogen gene and angiotensin I converting enzyme (ACE) gene polymorphisms in African Americans. Biochem Mol Biol Int 1994; 34: 1271-1275.
27. Farfel Z, Bourne HR, Iiri T. The expanding spectrum of G protein diseases. N Engl J Med 1999; 340: 1012-1020.
28. Iiri T, Farafel Z, Bourne HR. G-protein diseases furnish a model for the turn-on switch. Nature 1998; 394: 35-38.
29. Siffert W. G proteins and hypertension: an alternative to the candidate gene approach. Kidney Int 1998; 53: 1466-1470.
30. Siffert W et al. Enhanced G protein activation in immortalized lymphoblasts from patients with essential hypertension. J Clin Invest 1995; 96: 759-766.
31. Beigo J, Hohenbleicher H, Distler A, Sharma AM. G-Protein beta3 subunit C825T variant and ambulatory blood pressure in essential hypertension. Hypertension 1999; 33: 1049-1051.
32. Siffert W et al. Association of human G-protein beta3 subunit variant with hypertension. Nat Genet 1998; 18: 45-48.
33. Benjafield AV et al. G-protein beta 3 subunit gene (GNB3) variant in causation of essential hypertension. Hypertension 1998; 32: 1094-1097.
34. Schunkert H et al. Association between a polymorphism in the G protein beta 3 subunit gene and lower renin and elevated diastolic blood pressure levels. Hypertension 1998; 32: 510-513.
35. Brand E et al. The 825C/T polymorphism of the G-protein subunit β-3 is not related to hypertension. Hypertension 1999; 33: 1175-1178.
36. Hegele RA et al. G protein beta 3 subunit gene variant and blood pressure variation in Canadian Oji-Cree. Hypertension 1998; 32: 688-692.
37. Dong Y et al. Association between the C825T polymorphism of the G protein β-3 subunit gene and hypertension in blacks. Hypertension 1999; 34: 1193-1196.
38. Siffert W et al. Worldwide ethnic distribution of G protein β3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals. J Am Soc Nephrol 1999; 10; 1921-1930.
39. Hyman DJ et al. Lower hypertension prevalence in first-generation African immigrants compared to US-born African Americans. Ethn Dis 2000; 10: 343-349.
40. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med 1997; 157: 2413-2446.
41. Miller SA, Dykes, DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated Cells. Nucleic Acids Res 1988; 16: 1212.
42. Russ A et al. Rapid detection of the hypertension-associated Met235-Thr allele of the human angiotensinogen gene. Hum Mol Genet 1993; 2: 609-610.
43. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensinogen converting enzyme gene. Nucleic Acids Res 1992; 20: 1433.
44. Cushman DW, Cheung HS. Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem Pharmacol 1971; 20: 1637-1648.
45. Miles LE. Properties, variants, and applications of the immunoradiometric assay method. Ricerca in Clinica e in Laboratorio 1975; 5: 59-72.
46. Sealey JE. Plasma renin activity and plasma prorenin. Clin Chem 1991; 37: 1811-1819.
47. Groff JL, Harp JB, DiGirolamo M. Simplified enzymatic assay of angiotensinogen-converting enzyme in serum. Clin Chem 1993; 39: 400-404.
48. National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI). Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity: The evidence report. US Government Press: Washington D.C., 1998.
49. Arday DR et al. State smoking prevalence estimates: a comparison of the Behavioral Risk Factor Surveillance System and current population surveys. Am J Public Health 1997; 87: 1665-1669.
50. National Center for Health Statistics (NCHS). Plan and operation of the Third National Health and Nutrition Examination Survey, 1988-1994. Vital Health Stat. 1 (32) (DHHS publication no. [PHS] 94-1308). US Department of Health and Human Services: Hyattsville, MD, 1994.
51. Shea S et al. Reliability of the Behavioral Risk Factor Survey in a triethnic population. Am J Epidemiol 1991; 133: 489-500.
52. Stein AD, Lederman RI, Shea S. The Behavioral Risk Factor Surveillance System questionnaire: its reliability in a statewide sample. Am J Public Health 1993; 83: 1768-1772.
53. Dupuy HJ. Self-representations of general psychological well-being of American adults. Paper presented at the American Public Health Association Meeting, Los Angeles, CA, 1987.
54. Fazio AF. A concurrent validational study of the NCHS General Well-Being Schedule. U.S. Department of Health, Education, and Welfare, National Center for Health Statistics (Vital & Health Statistics, Series 2, No, 73, DHEW Publication No. [HRA] 78-1347): Hyattsville, MD, 1977.
55. Monk M. Blood pressure awareness and psychological well-being in the Health and Nutrition Examination Survey. Clin Invest Med 1981; 4: 183-189.
56. Edwards DW et al. Test-taking and the stability of adjustment scales: can we assess patient deterioration? Evaluation Quarterly 1978; 2: 275-291.
57. Krieger N, Sidney S, Coakley E. Racial discrimination and skin color in the CARDIA Study: implications for public health research. Am J Public Health 1998; 88:1308-1313.
58. McNeilly MD et al. The perceived racism scale: a multidimensional assessment of the experience of white racism among African Americans. Ethn Dis 1996; 6; 154-166.
59. National Center for Health Statistics (NCHS). Population estimates and projections. Current population reports. Series P-25, Number 721. US Government Printing Office: Washington D.C., 1978.
60. Falkoner DS, Mackay TFC. Genetic constitution of a population. Introduction to quantitative genetics (4th edition). Longman Scientific and Technical: Essex, England, 1996.
61. Rotimi C et al. Polymorphisms of renin-angiotensin genes among Nigerians, Jamaicans, and African Americans, Hypertension 1996; 27: 558-563.
62. Kunz R et al. Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal. Hypertension 1997; 30: 1331-1337.
63. Rotimi C et al. Angiotensinogen gene in human hypertension: lack of association between the 235 T allele among African Americans. Hypertension 1994; 24: 591-594.
64. Sharma AM. The thrify-genotype hypothesis and its implications for the study of complex genetic disorders. J Mol Med 1998; 76: 568-571.
65. Schunkert H et al. Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass. Heart 1997; 77: 24-31.
66. Cooper R et al. The prevalence of hypertension in seven populations of West African origin. Am J Public Health 1997; 87: 160-168.
67. Kaufman JS et al. Obesity and hypertension prevalence in populations of African origin. Epidemiology 1996; 7: 398-405.
68. Liu K et al. Blood pressure in young blacks and whites: relevance of obesity and lifestyle factors in determining differences: The CARDIA Study. Circulation 1996; 93: 60-66.
69. Rostand SG. Ultraviolet light may contribute to geographical and racial blood pressure differences. Hypertension 1997; 30: 150-156.
70. Lindpaintner K. Genes, hypertension, and cardiac hypertrophy. N Engl J Med 1994; 330: 1678-1679.
71. Freeman V, Rotimi C, Cooper R. Hypertension prevalence, awareness, treatment, and control among African Americans in the 1990s. Estimates from the Maywood Cardiovascular Survey. Am J Prev Med 1996; 12: 177-185.