Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos

Genes and Development

Volumn 14, Issue 3, 2000, Pages 313-327

  Stancheva, Irina ^a   Median, Richard R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

5 Methylcytosine; Antisense RNA; DNA methyltransferase; MBT; Xenopus

Indexed keywords

COMPLEMENTARY RNA; DNA METHYLTRANSFERASE;

ANIMAL CELL; ARTICLE; BLASTULA; CELL CYCLE; DNA METHYLATION; DNA REPLICATION; GENE ACTIVATION; IMMEDIATE EARLY GENE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; XENOPUS; ZYGOTE;

5-METHYLCYTOSINE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DIFFERENTIATION; CYTOSINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EMBRYO, NONMAMMALIAN; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HUMANS; MICE; MICROINJECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, ANTISENSE; T-BOX DOMAIN PROTEINS; XENOPUS LAEVIS; XENOPUS PROTEINS;

AMPHIBIA; ANIMALIA; CERBERUS; REPTILIA; VERTEBRATA; XENOPUS LAEVIS;

EID: 0343485074     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Almouzni, G. and A.P. Wolffe. 1995. Constraints on transcriptional activator function contribute to transcriptional quiescence during early Xenopus embryogenesis. EMBO J. 14: 1752-1765.
2. Artinger, M., I. Blitz, K. Inoue, U. Tran, and K.W. Cho. 1997. Interaction of goosecoid and brachyury in Xenopus mesoderm patterning. Mech. Dev. 65: 187-196.
3. Bestor, T.H. and V.M. Ingram. 1983. Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA. Proc. Natl. Acad. Sci. 80: 5559-5563.
4. Bird, A. 1992. The essentials of DNA methylation. Cell 70: 5-8.
5. Bouvet, P., S. Dimitrov, and A.P. Wolffe. 1994. Specific regulation of Xenopus chromosomal 5S rRNA gene transcription in vivo by histone H1. Genes & Dev. 8: 1147-1159.
6. Bouwmeester, T., S. Kim, Y. Sasai, B. Lu, and E.M. De Robertis. 1996. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382: 595-601.
7. Carlson, L.L., A.W. Page, and T.H. Bestor. 1992. Properties and localization of DNA methyltransferase in preimplantation mouse embryos: Implications for genomic imprinting. Genes & Dev. 6: 2536-2541.
8. Colot, V. and J.-L. Rossignol. 1999. Eukaryotic DNA methylation as a evolutionary device. BioEssays 21: 402-411.
9. Evans, J.P. and B.K. Kay. 1991. Biochemical fractionation of oocytes. Methods Cell Biol. 36: 133-148.
10. Goto, K., M. Numata, J.I. Komura, T. Ono, T.H. Bestor, and H. Kondo. 1994. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56: 39-44.
11. Gurdon, J.B., R.A. Laskey, and O.R. Reeves. 1975. The developmental capacity of nuclei transplanted from keratinized skin cells of adult frogs. J. Embryol. Exp. Morphol. 34: 93-112.
12. Harland, R.M. 1991. In situ hybridization: An improved wholemount method for Xenopus embryos. Methods Cell Biol. 36: 685-695.
13. Harland, R. and J. Gerhart. 1997. Formation and function of Spemann's organizer. Annu. Rev. Cell. Dev. Biol. 13:611-667.
14. Heasman, J. 1997. Patterning the Xenopus blastula. Development 124: 4179-4191.
15. Howe, J.A. and J.W. Newport. 1996. A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis. Proc. Natl. Acad. Sci. 93: 2060-2064.
16. Issacs, H.V., D. Tannahill, and J.M.W. Slack. 1992. Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification. Development 114: 711-720.
17. Jones, P.L., G.J. Veenstra, P.A. Wade, D. Vermaak, S.U. Kass, N. Landsberger, J. Strouboulis, and A.P. Wolffe. 1998. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19: 187-191.
18. Kandolf, H. 1994. The H1A histone variant is an in vivo represser of oocyte-type 5S gene transcription in Xenopus laevis embryos. Proc. Natl. Acad. Sci. 91: 7257-7261.
19. Kass, S.U., N. Landsberger, and A.P. Wolffe. 1997a. DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol. 7: 157-165.
20. Kass, S.U., D. Pruss, and A.P. Wolffe. 1997b. How does DNA methylation repress transcription? Trends Genet. 13: 444-449.
21. Kimura, H., G. Ishihara, and S. Tajima. 1996. Isolation and expression of a Xenopus laevis DNA methyltransferase cDNA. J. Biochem. (Tokyo) 120: 1182-1189.
22. Kimura, H., I. Suetake, and S. Tajima. 1999. Xenopus maintenance-type DNA methyltransferase is accumulated and translocated into germinal vesicles of oocytes. J. Biochem. (Tokyo) 125: 1175-1182.
23. Kinoshita, K., T. Bessho, and M. Asashima. 1993. Competence prepattern in the animal hemisphere of the 8-cell-stage Xenopus embryo. Dev. Biol. 160: 276-284.
24. Latinkic, B.V., M. Umbhauer, K.A. Neal, W. Lerchner, J.C. Smith, and V. Cunliffe. 1997. The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes & Dev. 11: 3265-3276.
25. Lei, H., S.P. Oh, M. Okano, R. Juttermann, K.A. Goss, R. Jaenisch, and E. Li. 1996. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122: 3195-3205.
26. Li, E., T.H. Bestor, and R. Jaenisch. 1992. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915-926.
27. Li, E., C. Beard, and R. Jaenisch. 1993. Role for DNA methylation in genomic imprinting. Nature 366: 362-365.
28. Liu, Y., E.J. Oakeley, L. Sun, and J.P. Jost. 1998. Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci. Nucleic Acids Res. 26: 1038-1045.
29. Lombardo, A. and J.M. Slack. 1997. Inhibition of eFGF expression in Xenopus embryos by antisense mRNA. Dev. Dyn. 208: 162-169.
30. Macleod, D., V. Clark, and A.P. Bird. 1999. Absence of genomewide changes in DNA methylation during development of the zebrafish (Danio rerio). Nat. Genet. 23: 139-140.
31. Martin, C.C., L. Laforest, M.A. Akimenko, and M. Ekker. 1999. A role for DNA methylation in gastrulation and somite patterning. Dev. Biol. 206: 189-205.
32. Mertineit, C., J.A. Yoder, T. Taketo, D.W. Laird, J.M. Trasler, and T.H. Bestor. 1998. Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development 125: 889-897.
33. Monk, M., M. Boubelik, and S. Lehnert. 1987. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99: 371-382.
34. Nan, X., F.J. Campoy, and A. Bird. 1997. MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88: 471-481.
35. Nan, X., H.H. Ng, C.A. Johnson, C.D. Laherty, B.M. Turner, R.N. Eisenman, and A. Bird. 1998. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393: 386-389.
36. Newport, J. and M. Kirschner. 1982a. A major developmental transition in early Xenopus embryos: I. Characterization and timing of cellular changes at the midblastula stage. Cell 30: 675-686.
37. _. 1982b. A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 30: 687-696.
38. Nieuwkoop, P.D. and J. Faber. 1967. Normal table of Xenopus (Daudin). Elsevier North Holland, Amsterdam, The Netherlands.
39. Okano, M., S. Xie, and E. Li. 1998. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19: 219-220
40. Pannese, M., C. Polo, M. Andreazzoli, R. Vignali, B. Kablar, G. Barsacchi, and E. Boncinelli. 1995. The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions. Development 121: 707-720.
41. Panning, B. and R. Jaenisch. 1996. DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes & Dev. 10: 1991-2002.
42. Pradhan, S., D. Talbot, M. Sha, J. Benner, L. Homstra, E. Li, R. Jaenisch, and R.J. Roberts. 1997. Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase. Nucleic Acids Res. 25: 4666-4673.
43. Prioleau, M.N., J. Huet, A. Sentenac, and M. Mechali. 1994. Competition between chromatin and transcription complex assembly regulates gene expression during early development. Cell 77: 439-449.
44. Razin, A. and T. Kafri. 1994. DNA methylation from embryo to adult. Prog. Nucleic Acid Res. Mol. Biol. 48: 53-81.
45. Reynaud, C., C. Bruno, P. Boullanger, J. Grange, S. Barbesti, and A. Niveleau. 1992. Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodies. Cancer Lett. 61: 255-262.
46. Singer-Sam, J., M. Grant, J.M. LeBon, K. Okuyama, V. Chapman, M. Monk, and A.D. Riggs. 1990. Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation. Mol. Cell. Biol. 10: 4987-4989.
47. Smith, J.C. B.M. Price, J.B. Green, D. Weigel, and B.C. Herrmann. 1991. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67: 79-87.
48. Steinbach, O.C., A.P. Wolffe, and R.A. Rupp. 1997. Somatic linker histones cause loss of mesodermal competence in Xenopus. Nature 389: 395-399.
49. Steinbeisser, H., A. Fainsod, C. Niehrs, Y. Sasai, and E.M. De Robertis. 1995. The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: A loss-of-function study using antisense RNA. EMBO J. 14: 5230-5243.
50. Tate, P., W. Skarnes, and A. Bird. 1996. The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nat. Genet. 12: 205-208.
51. Thiebaud, C.H., B. Colombelli, and W.P. Muller. 1984. Diploid gynogenesis in Xenopus laevis and the localization with respect to the centromere of the gene for periodic albinism ap. J. Embryol. Exp. Morphol. 83: 33-42.
52. Trasler, J.M., D.G. Trasler, T.H. Bestor, E. Li, and F. Ghibu. 1996. DNA methyltransferase in normal and Dnmtn/ Dnmtn mouse embryos. Dev. Dyn. 206: 239-247.
53. Tweedie, S., J. Charlton, V. Clark, and A. Bird. 1997. Methylation of genomes and genes at the invertebrate-vertebrate boundary. Mol. Cell. Biol. 17: 1469-1475.
54. Tymowska, J. 1991. Polyploidy and cytogenetic variation in frogs of the genus Xenopus. In Amphibian cytogenetics and evolution (ed. D.M. Green and S.K. Sessions), pp. 259-297. Academic Press, San Diego, CA.
55. Walsh, C.P. and T.H. Bestor. 1999. Cytosine methylation and mammalian development. Genes & Dev. 13: 26-34.
56. Waseem, N.H. and D.P. Lane. 1990. Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of the nucleoar form. J. Cell Sci. 96: 121-129.
57. Wilson, P.A. and D.A. Melton. 1994. Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr. Biol. 4: 676-686.
58. Wolpert, L., R. Beddington, J. Brockes, T. Jessel, P. Lawrence, and E. Meyerowitz 1998. Principles of development, 1st ed. Oxford University Press, Oxford, UK.
59. Yamada, Y., Y. Hagiwara, K. Shiokawa, Y. Sakaki, and T. Ito. 1999. Spatiotemporal, allelic, and enforced expression of Ximpact, the Xenopus homolog of mouse imprinted gene impact. Biochem. Biophys. Res. Commun. 256: 162-169.