메뉴 건너뛰기




Volumn 4, Issue 3, 1998, Pages 172-184

ORL-1: An awkward child of the opioid receptor family

Author keywords

Antiopioid; Dynorphin; Nociceptin; Nociception; Opioid receptor; ORL 1; Orphan; Orphanin FQ

Indexed keywords

DELTA OPIATE RECEPTOR; DYNORPHIN; KAPPA OPIATE RECEPTOR; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NOCICEPTIN; OPIATE RECEPTOR; ORL 1 RECEPTOR; UNCLASSIFIED DRUG;

EID: 0031835587     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849800400313     Document Type: Review
Times cited : (16)

References (110)
  • 1
    • 0030472350 scopus 로고    scopus 로고
    • International Union of Pharmacology. XII. Classification of opioid receptors
    • Dhawan BN, Cesselin F, Raghubir R, et al. International Union of Pharmacology. XII. Classification of opioid receptors. Pharmacol Rev 1996;48:567-592.
    • (1996) Pharmacol Rev , vol.48 , pp. 567-592
    • Dhawan, B.N.1    Cesselin, F.2    Raghubir, R.3
  • 2
    • 0031058863 scopus 로고    scopus 로고
    • Rapid opioid detoxification using opioid antagonists: History, theory and the state of the art
    • Simon DL. Rapid opioid detoxification using opioid antagonists: history, theory and the state of the art. J Addict Dis 1997;16: 103-122.
    • (1997) J Addict Dis , vol.16 , pp. 103-122
    • Simon, D.L.1
  • 3
    • 0024459590 scopus 로고
    • Multiple opioid receptors: Ligand selectivity profiles and binding site signatures
    • Goldstein A, Naidu A. Multiple opioid receptors: ligand selectivity profiles and binding site signatures. Mol Pharmacol 1989; 36:265-272.
    • (1989) Mol Pharmacol , vol.36 , pp. 265-272
    • Goldstein, A.1    Naidu, A.2
  • 5
    • 0029609445 scopus 로고
    • Molecular pharmacology of the opioid receptors
    • Satoh M, Minami M. Molecular pharmacology of the opioid receptors. Pharmacol Ther 1995;68:343-364.
    • (1995) Pharmacol Ther , vol.68 , pp. 343-364
    • Satoh, M.1    Minami, M.2
  • 6
    • 0029417155 scopus 로고
    • Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides
    • Kieffer BL. Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell Mol Neurobiol 1995;15:615-635.
    • (1995) Cell Mol Neurobiol , vol.15 , pp. 615-635
    • Kieffer, B.L.1
  • 7
    • 0029102878 scopus 로고
    • Molecular biology of the opioid receptors: Structures, functions and distributions
    • Minami M, Satoh M. Molecular biology of the opioid receptors: structures, functions and distributions. Neurosci Res 1995;23: 121-145.
    • (1995) Neurosci Res , vol.23 , pp. 121-145
    • Minami, M.1    Satoh, M.2
  • 8
    • 10544231050 scopus 로고    scopus 로고
    • Moving from the orphanin FQ receptor to an opioid receptor using four point mutations
    • Meng F, Taylor LP, Hoversten MT, et al. Moving from the orphanin FQ receptor to an opioid receptor using four point mutations. J Biol Chem 1996;271:32016-32020.
    • (1996) J Biol Chem , vol.271 , pp. 32016-32020
    • Meng, F.1    Taylor, L.P.2    Hoversten, M.T.3
  • 9
    • 0030583390 scopus 로고    scopus 로고
    • Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids
    • Mollereau C, Moisand C, Butour JL, Parmentier M, Meunier JC. Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids. FEBS Lett 1996;395:17-21.
    • (1996) FEBS Lett , vol.395 , pp. 17-21
    • Mollereau, C.1    Moisand, C.2    Butour, J.L.3    Parmentier, M.4    Meunier, J.C.5
  • 10
    • 0030597209 scopus 로고    scopus 로고
    • Dissociation of affinity and efficacy in KOR-3 chimeras
    • Pan YX, Xu J, Ryan-Moro J, et al. Dissociation of affinity and efficacy in KOR-3 chimeras. FEBS Lett 1996;395:207-210.
    • (1996) FEBS Lett , vol.395 , pp. 207-210
    • Pan, Y.X.1    Xu, J.2    Ryan-Moro, J.3
  • 11
    • 0028656442 scopus 로고
    • Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C)
    • Nishi M, Takeshima H, Mori M, Nakagawara K, Takeuchi T. Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C). Biochem Biophys Res Commun 1994;205:1353-1357.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1353-1357
    • Nishi, M.1    Takeshima, H.2    Mori, M.3    Nakagawara, K.4    Takeuchi, T.5
  • 12
    • 0028225109 scopus 로고
    • cDNA cloning of an orphan opiate receptor gene family member and its splice variant
    • Wang JB, Johnson PS, Imai Y, et al. cDNA cloning of an orphan opiate receptor gene family member and its splice variant. FEBS Lett 1994;348:75-79.
    • (1994) FEBS Lett , vol.348 , pp. 75-79
    • Wang, J.B.1    Johnson, P.S.2    Imai, Y.3
  • 13
    • 0029076795 scopus 로고
    • Functional role and sequence analysis of a lymphocyte orphan opioid receptor
    • Halford WP, Gebhardt BM, Carr DJ. Functional role and sequence analysis of a lymphocyte orphan opioid receptor. J Neuroimmunol 1995;59:91-101.
    • (1995) J Neuroimmunol , vol.59 , pp. 91-101
    • Halford, W.P.1    Gebhardt, B.M.2    Carr, D.J.3
  • 14
    • 0028072363 scopus 로고
    • Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors
    • Wick MJ, Minnerath SR, Lin X, Elde R, Law PY, Loh HH. Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors. Mol Brain Res 1994;27:37-44.
    • (1994) Mol Brain Res , vol.27 , pp. 37-44
    • Wick, M.J.1    Minnerath, S.R.2    Lin, X.3    Elde, R.4    Law, P.Y.5    Loh, H.H.6
  • 17
    • 0027471855 scopus 로고
    • Pharmacological mechanisms of opioid analgesics
    • Pasternak GW. Pharmacological mechanisms of opioid analgesics. Clin Neuropharmacol 1993;16:1-18.
    • (1993) Clin Neuropharmacol , vol.16 , pp. 1-18
    • Pasternak, G.W.1
  • 18
    • 0028226886 scopus 로고
    • ORL1, a novel member of the opioid receptor family: Cloning, functional expression and localization
    • Mollereau C, Parmentier M, Mailleux P, et al. ORL1, a novel member of the opioid receptor family: cloning, functional expression and localization. FEBS Lett 1994;341:33-38.
    • (1994) FEBS Lett , vol.341 , pp. 33-38
    • Mollereau, C.1    Parmentier, M.2    Mailleux, P.3
  • 19
    • 0028284167 scopus 로고
    • Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type
    • Bunzow JR, Saez C, Mortrud M, et al. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. FEBS Lett 1994;347:284-288.
    • (1994) FEBS Lett , vol.347 , pp. 284-288
    • Bunzow, J.R.1    Saez, C.2    Mortrud, M.3
  • 20
    • 0028308020 scopus 로고
    • Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family
    • Chen Y, Fan Y, Liu J, et al. Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett 1994;347:279-283.
    • (1994) FEBS Lett , vol.347 , pp. 279-283
    • Chen, Y.1    Fan, Y.2    Liu, J.3
  • 21
    • 0028279934 scopus 로고
    • cDNA cloning and regional distribution of a novel member of the opioid receptor family
    • Fukuda K, Kato S, Mori K, et al. cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett 1994;343:42-46.
    • (1994) FEBS Lett , vol.343 , pp. 42-46
    • Fukuda, K.1    Kato, S.2    Mori, K.3
  • 22
    • 0029121976 scopus 로고
    • Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines
    • Wick MJ, Minnerath SR, Roy S, Ramakrishnan S, Loh HH. Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines. Mol Brain Res 1995;32:342-347.
    • (1995) Mol Brain Res , vol.32 , pp. 342-347
    • Wick, M.J.1    Minnerath, S.R.2    Roy, S.3    Ramakrishnan, S.4    Loh, H.H.5
  • 23
    • 0030011981 scopus 로고    scopus 로고
    • Immunohistochemical localization of ORL-1 in the central nervous system of the rat
    • Anton B, Fein J, To T, Li X, Silberstein L, Evans CJ. Immunohistochemical localization of ORL-1 in the central nervous system of the rat. J Comp Neurol 1996;368:229-251.
    • (1996) J Comp Neurol , vol.368 , pp. 229-251
    • Anton, B.1    Fein, J.2    To, T.3    Li, X.4    Silberstein, L.5    Evans, C.J.6
  • 25
    • 0028139544 scopus 로고
    • Mu-, delta-, kappa-opioid receptors and their subtypes: A critical review with emphasis on radioligand binding experiments
    • Fowler CJ, Fraser GL. Mu-, delta-, kappa-opioid receptors and their subtypes: a critical review with emphasis on radioligand binding experiments. Neurochem Int 1994;24:401-426.
    • (1994) Neurochem Int , vol.24 , pp. 401-426
    • Fowler, C.J.1    Fraser, G.L.2
  • 26
    • 0028971215 scopus 로고
    • Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor
    • Reinscheid RK, Nothacker HP, Bourson A, et al. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 1995;270:792-794.
    • (1995) Science , vol.270 , pp. 792-794
    • Reinscheid, R.K.1    Nothacker, H.P.2    Bourson, A.3
  • 27
    • 0029166509 scopus 로고
    • Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
    • Meunier JC, Mollereau C, Toll L, et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 1995;377:532-535.
    • (1995) Nature , vol.377 , pp. 532-535
    • Meunier, J.C.1    Mollereau, C.2    Toll, L.3
  • 28
    • 0030933655 scopus 로고    scopus 로고
    • A potent and selective endogenous agonist for the mu-opiate receptor
    • Zadina JE, Hackler L, Ge LJ, Kastin AJ. A potent and selective endogenous agonist for the mu-opiate receptor. Nature 1997;386: 499-502.
    • (1997) Nature , vol.386 , pp. 499-502
    • Zadina, J.E.1    Hackler, L.2    Ge, L.J.3    Kastin, A.J.4
  • 29
    • 0029781358 scopus 로고    scopus 로고
    • Primary structure and tissue distribution of the orphanin FQ precursor
    • Nothacker HP, Reinscheid RK, Mansour A, et al. Primary structure and tissue distribution of the orphanin FQ precursor. Proc Natl Acad Sci U S A 1996;93:8677-8682.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8677-8682
    • Nothacker, H.P.1    Reinscheid, R.K.2    Mansour, A.3
  • 30
    • 0029738628 scopus 로고    scopus 로고
    • Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene
    • Mollereau C, Simons MJ, Soularue P, et al. Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Proc Natl Acad Sci U S A 1996;93:8666-8670.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8666-8670
    • Mollereau, C.1    Simons, M.J.2    Soularue, P.3
  • 31
    • 13144269964 scopus 로고    scopus 로고
    • Evidence for an alternatively spliced orphanin FQ mRNA in human fetal brain stem
    • Nov 30; New Orleans LA
    • Arjomand J, Evans CJ. Evidence for an alternatively spliced orphanin FQ mRNA in human fetal brain stem (abstract). Society for Neuroscience; 1997 Nov 30; New Orleans LA, p. 2318.
    • (1997) Society for Neuroscience , pp. 2318
    • Arjomand, J.1    Evans, C.J.2
  • 32
    • 0030929574 scopus 로고    scopus 로고
    • Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice
    • Florin S, Suaudeau C, Meunier JC, Costentin J. Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. Neuroreport 1997;8:705-707.
    • (1997) Neuroreport , vol.8 , pp. 705-707
    • Florin, S.1    Suaudeau, C.2    Meunier, J.C.3    Costentin, J.4
  • 33
    • 0029582742 scopus 로고
    • N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin
    • Saito Y, Maruyama K, Saido TC, Kawashima S. N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin. Biochem Biophys Res Commun 1995;217:539-545.
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 539-545
    • Saito, Y.1    Maruyama, K.2    Saido, T.C.3    Kawashima, S.4
  • 34
    • 0029978541 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule
    • Saito Y, Maruyama K, Kawano H, et al. Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule. J Biol Chem 1996;271: 15615-15622.
    • (1996) J Biol Chem , vol.271 , pp. 15615-15622
    • Saito, Y.1    Maruyama, K.2    Kawano, H.3
  • 35
    • 0030950804 scopus 로고    scopus 로고
    • Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/ N27K, induces neurite outgrowth in mouse NS20Y cells
    • Saito Y, Maruyama K, Saido TC, Kawashima S. Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/ N27K, induces neurite outgrowth in mouse NS20Y cells. J Neurosci Res 1997;48:397-406.
    • (1997) J Neurosci Res , vol.48 , pp. 397-406
    • Saito, Y.1    Maruyama, K.2    Saido, T.C.3    Kawashima, S.4
  • 36
    • 0029963540 scopus 로고    scopus 로고
    • Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor
    • Pan YX, Xu J, Pasternak GW. Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor. Biochem J 1996;315(Pt 1):11-13.
    • (1996) Biochem J , vol.315 , Issue.1 PART , pp. 11-13
    • Pan, Y.X.1    Xu, J.2    Pasternak, G.W.3
  • 38
    • 0029799611 scopus 로고    scopus 로고
    • Functional coupling of the delta-, mu-, and kappa-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells
    • Fukuda K, Kato S, Morikawa H, Shoda T, Mori K. Functional coupling of the delta-, mu-, and kappa-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells. J Neurochem 1996;67:1309-1316.
    • (1996) J Neurochem , vol.67 , pp. 1309-1316
    • Fukuda, K.1    Kato, S.2    Morikawa, H.3    Shoda, T.4    Mori, K.5
  • 39
    • 0027761786 scopus 로고
    • Drug addiction: A model for the molecular basis of neural plasticity
    • Nestler EJ, Hope BT, Widnell KL. Drug addiction: a model for the molecular basis of neural plasticity. Neuron 1993;11:995-1006.
    • (1993) Neuron , vol.11 , pp. 995-1006
    • Nestler, E.J.1    Hope, B.T.2    Widnell, K.L.3
  • 40
    • 0030462638 scopus 로고    scopus 로고
    • Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro
    • Connor M, Vaughan CW, Chieng B, Christie MJ. Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro. Br J Pharmacol 1996;119:1614-1618.
    • (1996) Br J Pharmacol , vol.119 , pp. 1614-1618
    • Connor, M.1    Vaughan, C.W.2    Chieng, B.3    Christie, M.J.4
  • 41
    • 0029658923 scopus 로고    scopus 로고
    • Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones
    • Vaughan CW, Christie MJ. Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones. Br J Pharmacol 1996;117:1609-1611.
    • (1996) Br J Pharmacol , vol.117 , pp. 1609-1611
    • Vaughan, C.W.1    Christie, M.J.2
  • 42
    • 0030614373 scopus 로고    scopus 로고
    • Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro
    • Vaughan CW, Ingram SL, Christie MJ. Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. J Neurosci 1997;17:996-1003.
    • (1997) J Neurosci , vol.17 , pp. 996-1003
    • Vaughan, C.W.1    Ingram, S.L.2    Christie, M.J.3
  • 43
    • 0029786552 scopus 로고    scopus 로고
    • Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes
    • Matthes H, Seward EP, Kieffer B, North RA. Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes. Mol Pharmacol 1996;50:447-450.
    • (1996) Mol Pharmacol , vol.50 , pp. 447-450
    • Matthes, H.1    Seward, E.P.2    Kieffer, B.3    North, R.A.4
  • 46
    • 0030003320 scopus 로고    scopus 로고
    • Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons
    • Knoflach F, Reinscheid RK, Civelli O, Kemp JA. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J Neurosci 1996;16:6657-6664.
    • (1996) J Neurosci , vol.16 , pp. 6657-6664
    • Knoflach, F.1    Reinscheid, R.K.2    Civelli, O.3    Kemp, J.A.4
  • 47
    • 0031002140 scopus 로고    scopus 로고
    • Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin
    • Patel HJ, Giembycz MA, Spicuzza L, Barnes PJ, Belvisi MG. Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin. Br J Pharmacol 1997;120:735-736.
    • (1997) Br J Pharmacol , vol.120 , pp. 735-736
    • Patel, H.J.1    Giembycz, M.A.2    Spicuzza, L.3    Barnes, P.J.4    Belvisi, M.G.5
  • 48
    • 0029901195 scopus 로고    scopus 로고
    • Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide
    • Giuliani S, Maggi CA. Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide. Br J Pharmacol 1996;118:1567-1569.
    • (1996) Br J Pharmacol , vol.118 , pp. 1567-1569
    • Giuliani, S.1    Maggi, C.A.2
  • 50
    • 0030936094 scopus 로고    scopus 로고
    • Inhibition by nociceptin of the light-evoked release of ACh from retinal cholinergic neurones
    • Neal MJ, Cunningham JR, Paterson SJ, McKnight AT. Inhibition by nociceptin of the light-evoked release of ACh from retinal cholinergic neurones. Br J Pharmacol 1997;120:1399-1400.
    • (1997) Br J Pharmacol , vol.120 , pp. 1399-1400
    • Neal, M.J.1    Cunningham, J.R.2    Paterson, S.J.3    McKnight, A.T.4
  • 53
    • 0029804988 scopus 로고    scopus 로고
    • Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide
    • Grisel JE, Mogil JS, Belknap JK, Grandy DK. Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide. Neuroreport 1996;7:2125-2129.
    • (1996) Neuroreport , vol.7 , pp. 2125-2129
    • Grisel, J.E.1    Mogil, J.S.2    Belknap, J.K.3    Grandy, D.K.4
  • 54
    • 0030598929 scopus 로고    scopus 로고
    • Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ
    • Mogil JS, Grisel JE, Zhangs G, Belknap JK, Grandy DK. Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ. Neurosci Lett 1996;214:131-134.
    • (1996) Neurosci Lett , vol.214 , pp. 131-134
    • Mogil, J.S.1    Grisel, J.E.2    Zhangs, G.3    Belknap, J.K.4    Grandy, D.K.5
  • 55
    • 8044238345 scopus 로고    scopus 로고
    • Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: Antagonism in brain and potentiation in spinal cord of the rat
    • Tian JH, Xu W, Fang Y, et al. Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat. Br J Pharmacol 1997;120:676-680.
    • (1997) Br J Pharmacol , vol.120 , pp. 676-680
    • Tian, J.H.1    Xu, W.2    Fang, Y.3
  • 56
    • 0030993313 scopus 로고    scopus 로고
    • Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia
    • Tian JH, Xu W, Zhang W, et al. Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia. Neuroreport 1997;8:497-500.
    • (1997) Neuroreport , vol.8 , pp. 497-500
    • Tian, J.H.1    Xu, W.2    Zhang, W.3
  • 57
    • 0030185169 scopus 로고    scopus 로고
    • Antagonistic action of orphanin FQ on acupuncture analgesia in rat brain
    • Zhu CB, Xu SF, Cao XD, et al. Antagonistic action of orphanin FQ on acupuncture analgesia in rat brain. Acupunct Electrother Res 1996;21:199-205.
    • (1996) Acupunct Electrother Res , vol.21 , pp. 199-205
    • Zhu, C.B.1    Xu, S.F.2    Cao, X.D.3
  • 58
    • 0242585042 scopus 로고    scopus 로고
    • Identification and characterization of an endogenous ligand for opioid receptor homologue ROR-C: Its involvement in allodynic response to innocuous stimulus
    • Okuda-Ashitaka E, Tachibana S, Houtani T, et al. Identification and characterization of an endogenous ligand for opioid receptor homologue ROR-C: its involvement in allodynic response to innocuous stimulus. Mol Brain Res 1996;43:96-104.
    • (1996) Mol Brain Res , vol.43 , pp. 96-104
    • Okuda-Ashitaka, E.1    Tachibana, S.2    Houtani, T.3
  • 59
    • 8244243943 scopus 로고    scopus 로고
    • Characterization of nociceptin hyperalgesia and allodynia in conscious mice
    • Hara N, Minami T, Okuda-Ashitaka E, et al. Characterization of nociceptin hyperalgesia and allodynia in conscious mice. Br J Pharmacol 1997;121:401-408.
    • (1997) Br J Pharmacol , vol.121 , pp. 401-408
    • Hara, N.1    Minami, T.2    Okuda-Ashitaka, E.3
  • 60
    • 0029806549 scopus 로고    scopus 로고
    • Nociceptin or antinociceptin: Potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat
    • Xu XJ, Hao JX, Wiesenfeld-Hallin Z. Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat. Neuroreport 1996;7:2092-2094.
    • (1996) Neuroreport , vol.7 , pp. 2092-2094
    • Xu, X.J.1    Hao, J.X.2    Wiesenfeld-Hallin, Z.3
  • 61
    • 0030945213 scopus 로고    scopus 로고
    • Effects of intrathecally administered nociceptin, an opioid receptor-like I (ORL1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat
    • Yamamoto T, Nozaki-Taguchi N, Kimura S. Effects of intrathecally administered nociceptin, an opioid receptor-like I (ORL1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat. Neurosci Lett 1997;224:107-110.
    • (1997) Neurosci Lett , vol.224 , pp. 107-110
    • Yamamoto, T.1    Nozaki-Taguchi, N.2    Kimura, S.3
  • 62
    • 0030937927 scopus 로고    scopus 로고
    • Effects of intrathecally administered nociceptin, an opioid receptor-like(1) (ORL1) receptor agonist, on the thermal hyperalgesia induced by carageenan injection into the rat paw
    • Yamamoto T, Nozaki-Taguchi N, Kimura S. Effects of intrathecally administered nociceptin, an opioid receptor-like(1) (ORL1) receptor agonist, on the thermal hyperalgesia induced by carageenan injection into the rat paw. Brain Res 1997;754:329-332.
    • (1997) Brain Res , vol.754 , pp. 329-332
    • Yamamoto, T.1    Nozaki-Taguchi, N.2    Kimura, S.3
  • 63
    • 0029818991 scopus 로고    scopus 로고
    • Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro
    • Faber ES, Chambers JP, Evans RH, Henderson G. Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro. Br J Pharmacol 1996;119:189-190.
    • (1996) Br J Pharmacol , vol.119 , pp. 189-190
    • Faber, E.S.1    Chambers, J.P.2    Evans, R.H.3    Henderson, G.4
  • 64
    • 0029814363 scopus 로고    scopus 로고
    • Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat in vivo
    • Stanfa LC, Chapman V, Kerr N, Dickenson AH. Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat in vivo. Br J Pharmacol 1996;118:1875-1877.
    • (1996) Br J Pharmacol , vol.118 , pp. 1875-1877
    • Stanfa, L.C.1    Chapman, V.2    Kerr, N.3    Dickenson, A.H.4
  • 65
    • 0030926028 scopus 로고    scopus 로고
    • Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord
    • Liebel JT, Swandulla D, Zeilhofer HU. Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord. Br J Pharmacol 1997; 121:425-132.
    • (1997) Br J Pharmacol , vol.121 , pp. 425-1132
    • Liebel, J.T.1    Swandulla, D.2    Zeilhofer, H.U.3
  • 66
    • 0031048438 scopus 로고    scopus 로고
    • Nociceptin (orphanin FQ) abolishes gestational and ovarian sex steroid-induced antinociception and induces hyperalgesia
    • Dawson-Basoa M, Gintzler AR. Nociceptin (orphanin FQ) abolishes gestational and ovarian sex steroid-induced antinociception and induces hyperalgesia. Brain Res 1997;750:48-52.
    • (1997) Brain Res , vol.750 , pp. 48-52
    • Dawson-Basoa, M.1    Gintzler, A.R.2
  • 69
    • 0030581496 scopus 로고    scopus 로고
    • Naloxone sensitive orphanin FQ-induced analgesia in mice
    • Rossi GC, Leventhal L, Pasternak GW. Naloxone sensitive orphanin FQ-induced analgesia in mice. Eur J Pharmacol 1996; 311(2-3):R7-R8.
    • (1996) Eur J Pharmacol , vol.311 , Issue.2-3
    • Rossi, G.C.1    Leventhal, L.2    Pasternak, G.W.3
  • 70
    • 0026784599 scopus 로고
    • A review of the role of anti-opioid peptides in morphine tolerance and dependence
    • Rothman RB. A review of the role of anti-opioid peptides in morphine tolerance and dependence. Synapse 1992;12:129-138.
    • (1992) Synapse , vol.12 , pp. 129-138
    • Rothman, R.B.1
  • 73
    • 0021951669 scopus 로고
    • Analgesic effects of dynorphin-A and morphine in mice
    • Nakazawa T, Ikeda M, Kaneko T, Yamatsu K. Analgesic effects of dynorphin-A and morphine in mice. Peptides 1985;6:75-78.
    • (1985) Peptides , vol.6 , pp. 75-78
    • Nakazawa, T.1    Ikeda, M.2    Kaneko, T.3    Yamatsu, K.4
  • 74
    • 0019382680 scopus 로고
    • Dynorphin: A possible modulatory peptide on morphine or beta-endorphin analgesia in mouse
    • Friedman HJ, Jen MF, Chang JK, Lee NM, Loh HH. Dynorphin: a possible modulatory peptide on morphine or beta-endorphin analgesia in mouse. Eur J Pharmacol 1981;69:357-360.
    • (1981) Eur J Pharmacol , vol.69 , pp. 357-360
    • Friedman, H.J.1    Jen, M.F.2    Chang, J.K.3    Lee, N.M.4    Loh, H.H.5
  • 75
    • 0019779623 scopus 로고
    • Possible regulatory role of dynorphin on morphine- and beta-endorphin-induced analgesia
    • Tulunay FC, Jen MF, Chang JK, Loh HH, Lee NM. Possible regulatory role of dynorphin on morphine- and beta-endorphin-induced analgesia. J Pharmacol Exp Ther 1981;219:296-298.
    • (1981) J Pharmacol Exp Ther , vol.219 , pp. 296-298
    • Tulunay, F.C.1    Jen, M.F.2    Chang, J.K.3    Loh, H.H.4    Lee, N.M.5
  • 76
    • 0022400254 scopus 로고
    • Dynorphin-A-(1-13) antagonizes morphine analgesia in the brain and potentiates morphine analgesia in the spinal cord
    • Ren MF, Lu CH, Han JS. Dynorphin-A-(1-13) antagonizes morphine analgesia in the brain and potentiates morphine analgesia in the spinal cord. Peptides 1985;6:1015-1020.
    • (1985) Peptides , vol.6 , pp. 1015-1020
    • Ren, M.F.1    Lu, C.H.2    Han, J.S.3
  • 77
    • 0029293997 scopus 로고
    • Comparative study of the analgesic and paralytic effects induced by intrathecal dynorphin a in rats
    • Xue JC, Yu YX, Han JS, Jen MF. Comparative study of the analgesic and paralytic effects induced by intrathecal dynorphin a in rats. Int J Neurosci 1995;82:83-93.
    • (1995) Int J Neurosci , vol.82 , pp. 83-93
    • Xue, J.C.1    Yu, Y.X.2    Han, J.S.3    Jen, M.F.4
  • 78
    • 0021992303 scopus 로고
    • Characterization of dynorphin A-induced antinociception at spinal level
    • Spampinato S, Candeletti S. Characterization of dynorphin A-induced antinociception at spinal level. Eur J Pharmacol 1985; 110:21-30.
    • (1985) Eur J Pharmacol , vol.110 , pp. 21-30
    • Spampinato, S.1    Candeletti, S.2
  • 79
    • 0021381221 scopus 로고
    • Dynorphin: Potent analgesic effect in spinal cord of the rat
    • Han JS, Xie CW. Dynorphin: potent analgesic effect in spinal cord of the rat. Sci Sin [B] 1984;27:169-177.
    • (1984) Sci Sin [B] , vol.27 , pp. 169-177
    • Han, J.S.1    Xie, C.W.2
  • 80
    • 0022599711 scopus 로고
    • Comparative spinal analgesic action of dynorphin 1-8, dynorphinl-13, and a kappa-receptor agonist U50,488
    • Jhamandas K, Sutak M, Lemaire S. Comparative spinal analgesic action of dynorphin 1-8, dynorphinl-13, and a kappa-receptor agonist U50,488. Can J Physiol Pharmacol 1986;64:263-268.
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 263-268
    • Jhamandas, K.1    Sutak, M.2    Lemaire, S.3
  • 81
    • 0021050782 scopus 로고
    • Sites of analgesic action of dynorphin
    • Kaneko T, Nakazawa T, Ikeda M, et al. Sites of analgesic action of dynorphin. Life Sci 1983; 33(1 Suppl):661-664.
    • (1983) Life Sci , vol.33 , Issue.1 SUPPL. , pp. 661-664
    • Kaneko, T.1    Nakazawa, T.2    Ikeda, M.3
  • 82
    • 0024420925 scopus 로고
    • Dynorphin A-induced rat hindlimb paralysis and spinal cord injury are not altered by the kappa opioid antagonist nor-binaltorphimine
    • Long JB, Rigamonti DD, de Costa B, Rice KC, Martinez-Arizala A. Dynorphin A-induced rat hindlimb paralysis and spinal cord injury are not altered by the kappa opioid antagonist nor-binaltorphimine. Brain Res 1989;497:155-162.
    • (1989) Brain Res , vol.497 , pp. 155-162
    • Long, J.B.1    Rigamonti, D.D.2    De Costa, B.3    Rice, K.C.4    Martinez-Arizala, A.5
  • 83
    • 0019275079 scopus 로고
    • Behavioral effects of dynorphin 1-13 in the mouse and rat: Initial observations
    • Walker JM, Katz RJ, Akil H. Behavioral effects of dynorphin 1-13 in the mouse and rat: initial observations. Peptides 1980;1: 341-345.
    • (1980) Peptides , vol.1 , pp. 341-345
    • Walker, J.M.1    Katz, R.J.2    Akil, H.3
  • 84
    • 0022592355 scopus 로고
    • Plasma extravasation induced by dynorphin-(1-13) in rat skin
    • Chahl LA, Chahl JS. Plasma extravasation induced by dynorphin-(1-13) in rat skin. Eur J Pharmacol 1986;124:343-347.
    • (1986) Eur J Pharmacol , vol.124 , pp. 343-347
    • Chahl, L.A.1    Chahl, J.S.2
  • 85
    • 0028990456 scopus 로고
    • [Des-Tyr1]dynorphin A-(2-17) has naloxone-insensitive antinociceptive effect in the writhing assay
    • Hooke LP, He L, Lee NM. [Des-Tyr1]dynorphin A-(2-17) has naloxone-insensitive antinociceptive effect in the writhing assay. J Pharmacol Exp Ther 1995;73:802-807.
    • (1995) J Pharmacol Exp Ther , vol.73 , pp. 802-807
    • Hooke, L.P.1    He, L.2    Lee, N.M.3
  • 86
    • 0026730434 scopus 로고
    • Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice
    • Takemori AE, Loh HH, Lee NM. Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice. Eur J Pharmacol 1992;221:223-226.
    • (1992) Eur J Pharmacol , vol.221 , pp. 223-226
    • Takemori, A.E.1    Loh, H.H.2    Lee, N.M.3
  • 87
    • 0028903447 scopus 로고
    • Dynorphin A modulates acute and chronic opioid effects
    • Hooke LP, He L, Lee NM. Dynorphin A modulates acute and chronic opioid effects. J Pharmacol Exp Ther 1995;273:292-297.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 292-297
    • Hooke, L.P.1    He, L.2    Lee, N.M.3
  • 89
    • 0030983770 scopus 로고    scopus 로고
    • Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor
    • Nishi M, Houtani T, Noda Y, et al. Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor. EMBO J 1997;16:1858-1864.
    • (1997) EMBO J , vol.16 , pp. 1858-1864
    • Nishi, M.1    Houtani, T.2    Noda, Y.3
  • 90
    • 0029091343 scopus 로고
    • Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor
    • Zhang S, Yu L. Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor. J Biol Chem 1995;270:22772-22776.
    • (1995) J Biol Chem , vol.270 , pp. 22772-22776
    • Zhang, S.1    Yu, L.2
  • 92
    • 0028080298 scopus 로고
    • Non-opioid effects of dynorphins: Possible role of the NMDA receptor
    • 91a. Shukla VK, Lemaire S. Non-opioid effects of dynorphins: possible role of the NMDA receptor. Trends Pharmacol Sci 1994; 15:420-424.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 420-424
    • Shukla, V.K.1    Lemaire, S.2
  • 93
    • 0024456225 scopus 로고
    • Opiate reward: Sites and substrates
    • Wise RA. Opiate reward: sites and substrates. Neurosci Biobehav Rev 1989;13:129-133.
    • (1989) Neurosci Biobehav Rev , vol.13 , pp. 129-133
    • Wise, R.A.1
  • 95
    • 0030586364 scopus 로고    scopus 로고
    • The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion
    • Devine DP, Reinscheid RK, Monsma FJ Jr, Civelli O, Akil H. The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion. Brain Res 1996;727:225-229.
    • (1996) Brain Res , vol.727 , pp. 225-229
    • Devine, D.P.1    Reinscheid, R.K.2    Monsma Jr., F.J.3    Civelli, O.4    Akil, H.5
  • 96
    • 0029856934 scopus 로고    scopus 로고
    • Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ
    • Devine DP, Taylor L, Reinscheid RK, Monsma FJ Jr, Civelli O, Akil H. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ. Neurochem Res 1996;21:1387-1396.
    • (1996) Neurochem Res , vol.21 , pp. 1387-1396
    • Devine, D.P.1    Taylor, L.2    Reinscheid, R.K.3    Monsma Jr., F.J.4    Civelli, O.5    Akil, H.6
  • 97
    • 0029854933 scopus 로고    scopus 로고
    • Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats
    • Murphy NP, Ly HT, Maidment NT. Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats. Neuroscience 1996;75:1-4.
    • (1996) Neuroscience , vol.75 , pp. 1-4
    • Murphy, N.P.1    Ly, H.T.2    Maidment, N.T.3
  • 98
    • 0025107375 scopus 로고
    • The effects of opioid peptides on dopamine release in the nucleus accumbens: An in vivo microdialysis study
    • Spanagel R, Herz A, Shippenberg TS. The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. J Neurochem 1990;55:1734-1740.
    • (1990) J Neurochem , vol.55 , pp. 1734-1740
    • Spanagel, R.1    Herz, A.2    Shippenberg, T.S.3
  • 99
    • 0030581735 scopus 로고    scopus 로고
    • Nociceptin stimulates locomotion and exploratory behaviour in mice
    • Florin S, Suaudeau C, Meunier JC, Costentin J. Nociceptin stimulates locomotion and exploratory behaviour in mice. Eur J Pharmacol 1996;317:9-13.
    • (1996) Eur J Pharmacol , vol.317 , pp. 9-13
    • Florin, S.1    Suaudeau, C.2    Meunier, J.C.3    Costentin, J.4
  • 100
    • 0030934155 scopus 로고    scopus 로고
    • Orphanin FQ, agonist of orphan opioid receptor ORL1, stimulates feeding in rats
    • Pomonis JD, Billington CJ, Levine AS. Orphanin FQ, agonist of orphan opioid receptor ORL1, stimulates feeding in rats. Neuroreport 1996;8:369-371.
    • (1996) Neuroreport , vol.8 , pp. 369-371
    • Pomonis, J.D.1    Billington, C.J.2    Levine, A.S.3
  • 101
    • 0030933084 scopus 로고    scopus 로고
    • Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake
    • Stratford TR, Holahan MR, Kelley AE. Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake. Neuroreport 1997;8:423-426.
    • (1997) Neuroreport , vol.8 , pp. 423-426
    • Stratford, T.R.1    Holahan, M.R.2    Kelley, A.E.3
  • 102
    • 0001839551 scopus 로고    scopus 로고
    • Stimulation of ingestive behavior by preferential and selective opioid agonists
    • Cooper SJ, Clifton PG, editors. San Diego (CA): Academic Press
    • Gosnell BA, Levine AS. Stimulation of ingestive behavior by preferential and selective opioid agonists. In: Cooper SJ, Clifton PG, editors. Drug receptor subtypes and ingestive behavior. San Diego (CA): Academic Press; 1996. p. 147-166.
    • (1996) Drug Receptor Subtypes and Ingestive Behavior , pp. 147-166
    • Gosnell, B.A.1    Levine, A.S.2
  • 103
    • 0031050078 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats
    • Sandin J, Georgieva J, Schott PA, Ogren SO, Terenius L. Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats. Eur J Neurosci 1997;9:194-197.
    • (1997) Eur J Neurosci , vol.9 , pp. 194-197
    • Sandin, J.1    Georgieva, J.2    Schott, P.A.3    Ogren, S.O.4    Terenius, L.5
  • 104
    • 0029013236 scopus 로고
    • A role for hippocampal opioids in long-term functional plasticity
    • Morris BJ, Johnston HM. A role for hippocampal opioids in long-term functional plasticity. Trends Neurosci 1995;18:350-355.
    • (1995) Trends Neurosci , vol.18 , pp. 350-355
    • Morris, B.J.1    Johnston, H.M.2
  • 105
    • 0031018793 scopus 로고    scopus 로고
    • Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus
    • Yu TP, Fein J, Phan T, Evans CJ, Xie CW. Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus. Hippocampus 1997;7:88-94.
    • (1997) Hippocampus , vol.7 , pp. 88-94
    • Yu, T.P.1    Fein, J.2    Phan, T.3    Evans, C.J.4    Xie, C.W.5
  • 106
    • 0029802758 scopus 로고    scopus 로고
    • Regulation and distribution of members of the opioid receptor family
    • Monteillet-Agius G, Fein J, Phan T, et al. Regulation and distribution of members of the opioid receptor family. Proc West Pharmacol Soc 1996;39:69-70.
    • (1996) Proc West Pharmacol Soc , vol.39 , pp. 69-70
    • Monteillet-Agius, G.1    Fein, J.2    Phan, T.3
  • 107
    • 0029767435 scopus 로고    scopus 로고
    • Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord
    • Riedl M, Shuster S, Vulchanova L, Wang J, Loh HH, Elde R. Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord. Neuroreport 1996;7:1369-1372.
    • (1996) Neuroreport , vol.7 , pp. 1369-1372
    • Riedl, M.1    Shuster, S.2    Vulchanova, L.3    Wang, J.4    Loh, H.H.5    Elde, R.6
  • 108
    • 0030454376 scopus 로고    scopus 로고
    • Nociceptin/ orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions
    • Schulz S, Schreff M, Nuss D, Gramsch C, Hollt V. Nociceptin/ orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions. Neuroreport 1996;7:3021-3025.
    • (1996) Neuroreport , vol.7 , pp. 3021-3025
    • Schulz, S.1    Schreff, M.2    Nuss, D.3    Gramsch, C.4    Hollt, V.5
  • 109
    • 0029796366 scopus 로고    scopus 로고
    • Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide
    • Shimohigashi Y, Hatano R, Fujita T, et al. Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide. J Biol Chem 1996;271:23642-23645.
    • (1996) J Biol Chem , vol.271 , pp. 23642-23645
    • Shimohigashi, Y.1    Hatano, R.2    Fujita, T.3
  • 110
    • 0031043674 scopus 로고    scopus 로고
    • Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat
    • Hao JX, Wiesenfeld-Hallin Z, Xu XJ. Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat. Neurosci Lett 1997;223:49-52.
    • (1997) Neurosci Lett , vol.223 , pp. 49-52
    • Hao, J.X.1    Wiesenfeld-Hallin, Z.2    Xu, X.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.