메뉴 건너뛰기




Volumn 23, Issue 11, 2003, Pages 1251-1262

Translational Paradigms in Cerebrovascular Gene Transfer

Author keywords

Adenovirus; Cerebral vasospasm; Gene therapy; Nitric oxide; Subarachnoid hemorrhage

Indexed keywords

GENE PRODUCT;

EID: 0242658592     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WCB.0000093324.07718.D4     Document Type: Review
Times cited : (9)

References (82)
  • 1
    • 0036218374 scopus 로고    scopus 로고
    • Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries
    • Akiyama M, Eguchi D, Weiler D, O'Brien T, Kovesdi I, Scotland R, Sessa WC, Katusic ZS (2002) Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries. Stroke 33:1071-1076
    • (2002) Stroke , vol.33 , pp. 1071-1076
    • Akiyama, M.1    Eguchi, D.2    Weiler, D.3    O'Brien, T.4    Kovesdi, I.5    Scotland, R.6    Sessa, W.C.7    Katusic, Z.S.8
  • 2
    • 0033969628 scopus 로고    scopus 로고
    • Is intracellular brain pH a dependent factor in NOS inhibition during focal cerebral ischemia?
    • Anderson RE, Meyer FB (2000) Is intracellular brain pH a dependent factor in NOS inhibition during focal cerebral ischemia? Brain Res 856:220-226
    • (2000) Brain Res , vol.856 , pp. 220-226
    • Anderson, R.E.1    Meyer, F.B.2
  • 3
    • 0036362273 scopus 로고    scopus 로고
    • Gene therapy of human disease
    • Balicki D, Beutler E (2002) Gene therapy of human disease. Medicine 81:69-86
    • (2002) Medicine , vol.81 , pp. 69-86
    • Balicki, D.1    Beutler, E.2
  • 5
    • 0028886936 scopus 로고
    • Gene therapy - A novel form of drug delivery
    • Blau HM, Springer ML (1995) Gene therapy-a novel form of drug delivery. N Engl J Med 333:1204-1207
    • (1995) N Engl J Med , vol.333 , pp. 1204-1207
    • Blau, H.M.1    Springer, M.L.2
  • 6
    • 0028220671 scopus 로고
    • Nitric oxide directly activates calcium dependent potassium channels in vascular smooth muscle
    • Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA (1994) Nitric oxide directly activates calcium dependent potassium channels in vascular smooth muscle. Nature 368:850-853
    • (1994) Nature , vol.368 , pp. 850-853
    • Bolotina, V.M.1    Najibi, S.2    Palacino, J.J.3    Pagano, P.J.4    Cohen, R.A.5
  • 7
    • 0034149773 scopus 로고    scopus 로고
    • Reports of adenovector "death" are greatly exaggerated
    • Brenner M (2000) Reports of adenovector "death" are greatly exaggerated. Mol Ther 1:205
    • (2000) Mol Ther , vol.1 , pp. 205
    • Brenner, M.1
  • 8
    • 0035220588 scopus 로고    scopus 로고
    • Biologic alternatives to stents and grafts
    • Caplice NM (2001) Biologic alternatives to stents and grafts. Curr Cardiol Rep 3:17-21
    • (2001) Curr Cardiol Rep , vol.3 , pp. 17-21
    • Caplice, N.M.1
  • 9
    • 0030296392 scopus 로고    scopus 로고
    • Adenoviral gene transfer of nitric oxide synthase: High level expression in human vascular cells
    • Channon KM, Blazing MA, Shetty GA, Potts KE, George SE (1996) Adenoviral gene transfer of nitric oxide synthase: high level expression in human vascular cells. Cardiovasc Res 32:962-972
    • (1996) Cardiovasc Res , vol.32 , pp. 962-972
    • Channon, K.M.1    Blazing, M.A.2    Shetty, G.A.3    Potts, K.E.4    George, S.E.5
  • 11
    • 0032127042 scopus 로고    scopus 로고
    • Transfer and expression of recombinant nitric oxide synthase genes in the cardiovascular system
    • Chen AFY, O'Brien T, Katusic ZS (1998) Transfer and expression of recombinant nitric oxide synthase genes in the cardiovascular system. Trends Pharmacol Sci 19:276-286
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 276-286
    • Chen, A.F.Y.1    O'Brien, T.2    Katusic, Z.S.3
  • 14
    • 0027522920 scopus 로고
    • A model system for in vivo gene transfer into the central nervous system using an adenoviral vector
    • Davidson BL, Allen ED, Kozarsky KF, Wilson JM, Roessler BJ (1993) A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nat Genet 3:219-223
    • (1993) Nat Genet , vol.3 , pp. 219-223
    • Davidson, B.L.1    Allen, E.D.2    Kozarsky, K.F.3    Wilson, J.M.4    Roessler, B.J.5
  • 15
    • 0028318232 scopus 로고
    • Nitric oxide in the clinical arena
    • De Belder AJ, Radomski MW (1994) Nitric oxide in the clinical arena. J Hypertens 12:617-624
    • (1994) J Hypertens , vol.12 , pp. 617-624
    • De Belder, A.J.1    Radomski, M.W.2
  • 16
    • 0034021806 scopus 로고    scopus 로고
    • Molecular keys to the problems of cerebral vasospasm
    • Dietrich HH, Dacy RG Jr (2000) Molecular keys to the problems of cerebral vasospasm. Neurosurgery 46:517-530
    • (2000) Neurosurgery , vol.46 , pp. 517-530
    • Dietrich, H.H.1    Dacy Jr., R.G.2
  • 17
    • 0034152565 scopus 로고    scopus 로고
    • Progress and potential for gene-based medicines
    • Dyer MR, Herrling PL (2000) Progress and potential for gene-based medicines. Mol Ther 1:213-224
    • (2000) Mol Ther , vol.1 , pp. 213-224
    • Dyer, M.R.1    Herrling, P.L.2
  • 18
    • 0034774790 scopus 로고    scopus 로고
    • Protective effect of heme oxygenase-1 gene transfer against oxyhemoglobin endothelial dysfunction
    • Eguchi D, Weiler D, Alam J, Nath K, Katusic ZS (2001) Protective effect of heme oxygenase-1 gene transfer against oxyhemoglobin endothelial dysfunction. J Cereb Blood Flow Metab 21:1215-1222
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1215-1222
    • Eguchi, D.1    Weiler, D.2    Alam, J.3    Nath, K.4    Katusic, Z.S.5
  • 19
    • 0033566864 scopus 로고    scopus 로고
    • Signal transduction of eNOS activation
    • Fleming I, Busse R (1999) Signal transduction of eNOS activation. Cardiovasc Res 43:532-541
    • (1999) Cardiovasc Res , vol.43 , pp. 532-541
    • Fleming, I.1    Busse, R.2
  • 20
    • 0034978322 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for ischemic cardiovascular disease
    • Freedman S B, Isner JM (2001) Therapeutic angiogenesis for ischemic cardiovascular disease. J Mol Cell Cardiol 33:379-93
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 379-393
    • Freedman, S.B.1    Isner, J.M.2
  • 21
    • 0015492624 scopus 로고
    • Gene therapy for human genetic disease? Proposals for genetic manipulation in humans raise difficult scientific and ethical problems
    • Friedmann T, Roblin R (1972) Gene therapy for human genetic disease? Proposals for genetic manipulation in humans raise difficult scientific and ethical problems. Science 175:949-955
    • (1972) Science , vol.175 , pp. 949-955
    • Friedmann, T.1    Roblin, R.2
  • 23
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 26
    • 0036371309 scopus 로고    scopus 로고
    • Virally mediated gene transfer to the vasculature
    • Gunnett CA, Heistad DD (2002) Virally mediated gene transfer to the vasculature. Microcirculation 9:23-33
    • (2002) Microcirculation , vol.9 , pp. 23-33
    • Gunnett, C.A.1    Heistad, D.D.2
  • 27
    • 0036712982 scopus 로고    scopus 로고
    • Gene transfer of inducible nitric oxide synthase impairs relaxation in human and rabbit cerebral arteries
    • Gunnett CA, Lund DD, Howard MA III, Chu Y, Faraci FM, Heistad DD (2002) Gene transfer of inducible nitric oxide synthase impairs relaxation in human and rabbit cerebral arteries. Stroke 33:2292-2296
    • (2002) Stroke , vol.33 , pp. 2292-2296
    • Gunnett, C.A.1    Lund, D.D.2    Howard III, M.A.3    Chu, Y.4    Faraci, F.M.5    Heistad, D.D.6
  • 28
    • 0029796019 scopus 로고    scopus 로고
    • Gene therapy for cerebral vascular disease
    • Heistad DD, Faraci FM (1996) Gene therapy for cerebral vascular disease. Stroke 27:1688-1693
    • (1996) Stroke , vol.27 , pp. 1688-1693
    • Heistad, D.D.1    Faraci, F.M.2
  • 29
    • 0032948112 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase as a potential therapeutic target
    • Hobbs AJ, Higgs A, Moncada S (1999) Inhibition of nitric oxide synthase as a potential therapeutic target. Annu Rev Pharmacol Toxicol 39:191-220
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 191-220
    • Hobbs, A.J.1    Higgs, A.2    Moncada, S.3
  • 30
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay MA, Glorioso JC, Naldini L (2001) Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 7:33-40
    • (2001) Nat Med , vol.7 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 31
    • 0008193811 scopus 로고    scopus 로고
    • Pathophysiological basis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage
    • Khurana VG. Besser M (1997) Pathophysiological basis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Clin Neurosci 4:122-131
    • (1997) J Clin Neurosci , vol.4 , pp. 122-131
    • Khurana, V.G.1    Besser, M.2
  • 32
    • 0033762055 scopus 로고    scopus 로고
    • Functional interdependence and colocalization of endothelial nitric oxide synthase (eNOS) and heat-shock protein 90 (HSP90) in cerebral arteries
    • Khurana VG, Feterik K, Eguchi D, Springett MJ, Shah V, Katusic ZS (2000a) Functional interdependence and colocalization of endothelial nitric oxide synthase (eNOS) and heat-shock protein 90 (HSP90) in cerebral arteries. J Cereb Blood Flow Metab 20:1563-1570
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1563-1570
    • Khurana, V.G.1    Feterik, K.2    Eguchi, D.3    Springett, M.J.4    Shah, V.5    Katusic, Z.S.6
  • 33
    • 0035234518 scopus 로고    scopus 로고
    • Gene transfer for cerebrovascular disease
    • Khurana VG, Katusic ZS (2001) Gene transfer for cerebrovascular disease. Curr Cardiol Rep 3:10-16
    • (2001) Curr Cardiol Rep , vol.3 , pp. 10-16
    • Khurana, V.G.1    Katusic, Z.S.2
  • 34
    • 0036196152 scopus 로고    scopus 로고
    • Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm
    • Khurana VG, Smith LA, Baker TA, Eguchi D, O'Brien T, Katusic ZS (2002) Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm. Stroke 33:782-789
    • (2002) Stroke , vol.33 , pp. 782-789
    • Khurana, V.G.1    Smith, L.A.2    Baker, T.A.3    Eguchi, D.4    O'Brien, T.5    Katusic, Z.S.6
  • 37
    • 0033567070 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and vascular injury
    • Kibbe M, Billiar T, Tzeng E (1999) Inducible nitric oxide synthase and vascular injury. Cardiovasc Res 43:650-657
    • (1999) Cardiovasc Res , vol.43 , pp. 650-657
    • Kibbe, M.1    Billiar, T.2    Tzeng, E.3
  • 38
    • 0030883521 scopus 로고    scopus 로고
    • Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo
    • Kim S, Lin H, Barr E, Chu L, Leiden JM, Parmacek MS (1997) Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo. J Clin Invest 100:1006-1014
    • (1997) J Clin Invest , vol.100 , pp. 1006-1014
    • Kim, S.1    Lin, H.2    Barr, E.3    Chu, L.4    Leiden, J.M.5    Parmacek, M.S.6
  • 39
    • 0030754269 scopus 로고    scopus 로고
    • Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries
    • Kullo IJ, Mozes G, Schwartz RS, Gloviczki P, Tsutsui M, Katusic ZS, O'Brien T (1997) Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries. Hypertension 30:314-320
    • (1997) Hypertension , vol.30 , pp. 314-320
    • Kullo, I.J.1    Mozes, G.2    Schwartz, R.S.3    Gloviczki, P.4    Tsutsui, M.5    Katusic, Z.S.6    O'Brien, T.7
  • 43
    • 0032946678 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits
    • Lund DD, Faraci FM, Ooboshi H, Davidson BL, Heistad DD (1998) Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits. Stroke 29:120-125
    • (1998) Stroke , vol.29 , pp. 120-125
    • Lund, D.D.1    Faraci, F.M.2    Ooboshi, H.3    Davidson, B.L.4    Heistad, D.D.5
  • 44
    • 0023142591 scopus 로고
    • Focal cerebral ischemia: Pathophysiologic mechanisms and rationale for future avenues of treatment
    • Meyer FB, Sundt TM Jr, Yanagihara T, Anderson RE (1987) Focal cerebral ischemia: pathophysiologic mechanisms and rationale for future avenues of treatment. Mayo Clin Proc 62:35-55
    • (1987) Mayo Clin Proc , vol.62 , pp. 35-55
    • Meyer, F.B.1    Sundt Jr., T.M.2    Yanagihara, T.3    Anderson, R.E.4
  • 45
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 47
    • 0028883466 scopus 로고
    • Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia
    • Newman KD, Dunn PF, Owens JW, Schulick AH, Virmani R, Sukhova G, Libby P, Dichek DA (1995) Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J Clin Invest 96:2955-2965
    • (1995) J Clin Invest , vol.96 , pp. 2955-2965
    • Newman, K.D.1    Dunn, P.F.2    Owens, J.W.3    Schulick, A.H.4    Virmani, R.5    Sukhova, G.6    Libby, P.7    Dichek, D.A.8
  • 49
    • 0035983569 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene therapy for prevention of vasospasm in rats
    • Ono S, Komuro T, Macdonald RL (2002) Heme oxygenase-1 gene therapy for prevention of vasospasm in rats. J Neurosurg 96:1094-1102
    • (2002) J Neurosurg , vol.96 , pp. 1094-1102
    • Ono, S.1    Komuro, T.2    Macdonald, R.L.3
  • 50
    • 0033503523 scopus 로고    scopus 로고
    • Adventitial expression of recombinant endothelial nitric oxide synthase gene reverses vasoconstrictor effect of endothelin-1
    • Onoue H, Tsutsui M, Smith L, O'Brien T, Katusic ZS (1999) Adventitial expression of recombinant endothelial nitric oxide synthase gene reverses vasoconstrictor effect of endothelin-1. J Cereb Blood Flow Metab 19:1029-1037
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1029-1037
    • Onoue, H.1    Tsutsui, M.2    Smith, L.3    O'Brien, T.4    Katusic, Z.S.5
  • 51
    • 0031692410 scopus 로고    scopus 로고
    • Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage
    • Onoue H, Tsutsui M, Smith L, Stelter A, O'Brien T, Katusic ZS (1998) Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage. Stroke 29:1959-1966
    • (1998) Stroke , vol.29 , pp. 1959-1966
    • Onoue, H.1    Tsutsui, M.2    Smith, L.3    Stelter, A.4    O'Brien, T.5    Katusic, Z.S.6
  • 52
    • 0029061922 scopus 로고
    • Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue
    • Ooboshi H, Welsh MJ, Rios CD, Davidson BL, Heistad DD (1995) Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circ Res 77:7-13
    • (1995) Circ Res , vol.77 , pp. 7-13
    • Ooboshi, H.1    Welsh, M.J.2    Rios, C.D.3    Davidson, B.L.4    Heistad, D.D.5
  • 53
    • 0033767531 scopus 로고    scopus 로고
    • Principles of gene therapy: Potential applications in the treatment of cerebral ischemia
    • Papadopoulos MC, Giffard RG, Bell BA (2000) Principles of gene therapy: potential applications in the treatment of cerebral ischemia. Br J Neurosurg 14:407-414
    • (2000) Br J Neurosurg , vol.14 , pp. 407-414
    • Papadopoulos, M.C.1    Giffard, R.G.2    Bell, B.A.3
  • 54
    • 0029780523 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition by L-NAME prevents brain acidosis during focal cerebral ischemia in rabbits
    • Regli L, Held MC, Anderson RE, Meyer FB (1996) Nitric oxide synthase inhibition by L-NAME prevents brain acidosis during focal cerebral ischemia in rabbits. J Cereb Blood Flow Metab 16:988-995
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 988-995
    • Regli, L.1    Held, M.C.2    Anderson, R.E.3    Meyer, F.B.4
  • 56
    • 0036292179 scopus 로고    scopus 로고
    • Posttreatment with adenovirus-mediated gene transfer of calcitonin gene-related peptide to reverse cerebral vasospasm in dogs
    • Satoh M, Perkins E, Kimura H, Tang J, Chun Y, Heistad DD, Zhang JH (2002) Posttreatment with adenovirus-mediated gene transfer of calcitonin gene-related peptide to reverse cerebral vasospasm in dogs. J Neurosurg 97:136-142
    • (2002) J Neurosurg , vol.97 , pp. 136-142
    • Satoh, M.1    Perkins, E.2    Kimura, H.3    Tang, J.4    Chun, Y.5    Heistad, D.D.6    Zhang, J.H.7
  • 58
    • 0028967728 scopus 로고
    • Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo
    • Szabo C, Salzman AL, Ischiropoulos H (1995) Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo. FEBS Lett 363:235-238
    • (1995) FEBS Lett , vol.363 , pp. 235-238
    • Szabo, C.1    Salzman, A.L.2    Ischiropoulos, H.3
  • 59
    • 0034691208 scopus 로고    scopus 로고
    • Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic disease
    • Thomas CE, Schiedner G, Kochanek S, Castro MG, Lowenstein PR (2000) Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic disease. Proc Natl Acad Sci U S A 97:7482-7487
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7482-7487
    • Thomas, C.E.1    Schiedner, G.2    Kochanek, S.3    Castro, M.G.4    Lowenstein, P.R.5
  • 60
    • 0033027409 scopus 로고    scopus 로고
    • Safety of intrathecal sodium nitroprusside for the treatment and prevention of refractory cerebral vasospasm and ischemia in humans
    • Thomas JE, Rosenwasser RH, Armondo RA, Harrop J, Mitchell W, Galaria I (1999) Safety of intrathecal sodium nitroprusside for the treatment and prevention of refractory cerebral vasospasm and ischemia in humans. Stroke 30:1409-1416
    • (1999) Stroke , vol.30 , pp. 1409-1416
    • Thomas, J.E.1    Rosenwasser, R.H.2    Armondo, R.A.3    Harrop, J.4    Mitchell, W.5    Galaria, I.6
  • 61
    • 0033869749 scopus 로고    scopus 로고
    • Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessels in vitro and in vivo
    • Toyoda K, Andresen JJ, Zabner J, Faraci FM, Heistad DD (2000a) Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessels in vitro and in vivo. Gene Ther 7:1284-1291
    • (2000) Gene Ther , vol.7 , pp. 1284-1291
    • Toyoda, K.1    Andresen, J.J.2    Zabner, J.3    Faraci, F.M.4    Heistad, D.D.5
  • 63
  • 64
    • 0034840511 scopus 로고    scopus 로고
    • Cationic polymer and lipids augment adenovirus-mediated gene transfer to cerebral arteries in vivo
    • Toyoda K, Nakane H, Heistad DD (2001) Cationic polymer and lipids augment adenovirus-mediated gene transfer to cerebral arteries in vivo. J Cereb Blood Flow Metab 21:1125-1131
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1125-1131
    • Toyoda, K.1    Nakane, H.2    Heistad, D.D.3
  • 65
    • 0031866890 scopus 로고    scopus 로고
    • Adventitial expression of recombinant eNOS gene restores NO production in arteries without endothelium
    • Tsutsui M, Chen AFY, O'Brien T, Crotty TB, Katusic ZS (1998) Adventitial expression of recombinant eNOS gene restores NO production in arteries without endothelium. Anterioscler Thromb Vasc Biol 18:1231-1241
    • (1998) Anterioscler Thromb Vasc Biol , vol.18 , pp. 1231-1241
    • Tsutsui, M.1    Chen, A.F.Y.2    O'Brien, T.3    Crotty, T.B.4    Katusic, Z.S.5
  • 66
    • 0033003010 scopus 로고    scopus 로고
    • Adventitia-dependent relaxations of canine basilar arteries transduced with recombinant eNOS gene
    • Tsutsui M, Onoue H, Iida Y, Smith L, O'Brien T, Katusic ZS (1999) Adventitia-dependent relaxations of canine basilar arteries transduced with recombinant eNOS gene. Am J Physiol 276:H1846-H1852
    • (1999) Am J Physiol , vol.276
    • Tsutsui, M.1    Onoue, H.2    Iida, Y.3    Smith, L.4    O'Brien, T.5    Katusic, Z.S.6
  • 68
    • 0034107633 scopus 로고    scopus 로고
    • Effects of recombinant eNOS gene expression on reactivity of small cerebral arteries
    • Tsutsui M, Onoue H, Iida Y, Smith L, O'Brien T, Katusic ZS (2000b) Effects of recombinant eNOS gene expression on reactivity of small cerebral arteries. Am J Physiol 278:H420-H427
    • (2000) Am J Physiol , vol.278
    • Tsutsui, M.1    Onoue, H.2    Iida, Y.3    Smith, L.4    O'Brien, T.5    Katusic, Z.S.6
  • 69
    • 0027969016 scopus 로고
    • Moyamoya disease: The disorder and surgical treatment
    • Ueki K, Meyer FB, Mellinger JF (1994) Moyamoya disease: the disorder and surgical treatment. Mayo Clin Proc 69:749-757
    • (1994) Mayo Clin Proc , vol.69 , pp. 749-757
    • Ueki, K.1    Meyer, F.B.2    Mellinger, J.F.3
  • 70
    • 0032810015 scopus 로고    scopus 로고
    • How to assess endothelial function in human blood vessels
    • Vanhoutte PM (1999) How to assess endothelial function in human blood vessels. J Hypertens 17:1047-1058
    • (1999) J Hypertens , vol.17 , pp. 1047-1058
    • Vanhoutte, P.M.1
  • 71
    • 16244410439 scopus 로고    scopus 로고
    • A mouse model of arterial gene transfer: Antigen-specific immunity is a minor determinant of the early loss of adenovirus-mediated transgene expression
    • Vassalli G, Agah R, Qiao R, Aguilar C, Dichek DA (1999) A mouse model of arterial gene transfer: antigen-specific immunity is a minor determinant of the early loss of adenovirus-mediated transgene expression. Circ Res 85:e25-e32
    • (1999) Circ Res , vol.85
    • Vassalli, G.1    Agah, R.2    Qiao, R.3    Aguilar, C.4    Dichek, D.A.5
  • 72
    • 0037303466 scopus 로고    scopus 로고
    • A voluntary moratorium?
    • Verma IM (2003) A voluntary moratorium? Mol Ther 7:141
    • (2003) Mol Ther , vol.7 , pp. 141
    • Verma, I.M.1
  • 75
    • 0037319344 scopus 로고    scopus 로고
    • Gene transfer of extracellular superoxide dismutase reduces cerebral vasospasm after subarachnoid hemorrhage
    • Watanabe Y, Chu Y, Andresen JJ, Nakane H, Faraci FM, Heistad DD (2003) Gene transfer of extracellular superoxide dismutase reduces cerebral vasospasm after subarachnoid hemorrhage. Stroke 34:434-440
    • (2003) Stroke , vol.34 , pp. 434-440
    • Watanabe, Y.1    Chu, Y.2    Andresen, J.J.3    Nakane, H.4    Faraci, F.M.5    Heistad, D.D.6
  • 77
    • 0029031779 scopus 로고
    • The pathophysiology of cerebral vasospasm
    • Weir B (1995) The pathophysiology of cerebral vasospasm. Br J Neurosurg 9:375-390
    • (1995) Br J Neurosurg , vol.9 , pp. 375-390
    • Weir, B.1
  • 78
    • 0034082167 scopus 로고    scopus 로고
    • Second-generation adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall
    • Wen S, Schneider DB, Driscoll RM, Vassalli G, Sassani AB, Dichek DA (2000) Second-generation adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall. Anterioscler Thromb Vasc Biol 20:1452-1458
    • (2000) Anterioscler Thromb Vasc Biol , vol.20 , pp. 1452-1458
    • Wen, S.1    Schneider, D.B.2    Driscoll, R.M.3    Vassalli, G.4    Sassani, A.B.5    Dichek, D.A.6
  • 81
    • 0037047039 scopus 로고    scopus 로고
    • Positron emission tomography imaging of cardiac reporter gene expression in living rats
    • Wu JC, Inubushi M, Sundaresan G, Schelbert HR, Gambhir SS (2002) Positron emission tomography imaging of cardiac reporter gene expression in living rats. Circulation 106:180-183
    • (2002) Circulation , vol.106 , pp. 180-183
    • Wu, J.C.1    Inubushi, M.2    Sundaresan, G.3    Schelbert, H.R.4    Gambhir, S.S.5
  • 82
    • 0034942540 scopus 로고    scopus 로고
    • Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors
    • Yenari MA, Dumas TC, Sapolsky RM, Steinberg GK (2001) Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors. Ann N Y Acad Sci 939:340-357
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 340-357
    • Yenari, M.A.1    Dumas, T.C.2    Sapolsky, R.M.3    Steinberg, G.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.