The future of gene therapy for stroke

Current Hypertension Reports

Volumn 3, Issue 1, 2001, Pages 36-40

  Gunnett, Carol A ^a   Heistad, Donald D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEREBROVASCULAR ACCIDENT; FORECASTING; GENE THERAPY; HUMAN; REVIEW;

CEREBROVASCULAR ACCIDENT; FORECASTING; GENE THERAPY; HUMANS;

EID: 0035257293     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-001-0076-9     Document Type: Article

References (50)

1. Tsutsui M, Onoue H, Iida Y, et al.: Effects of recombinant eNOS gene expression on reactivity of small cerebral arteries. Am J Physiol Heart Circ Physiol 2000, 278: H420-H427.
2. Toyoda K, Faraci FM, Russo AF, et al.: Gene transfer of calcitonin gene-related peptide to cerebral arteries. Am J Physiol Heart Circ Physiol 2000, 278: H586-H594.
3. Khurana VG, Smith LA, Weiler DA, et al.: Adenovirus-mediated gene transfer to human cerebral arteries. J Cereb Blood Flow Metab 2000, 20: 1360-1371.
4. Yang GY, Mao Y, Zhou LF, et al.: Attenuation of temporary focal cerebral ischemic injury in the mouse following transfection with interleukin-1 receptor antagonist. Brain Res Mol Brain Res 1999, 72: 129-137.
5. Lund DD, Faraci FM, Ooboshi H, et al.: Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits. Stroke 1999, 30: 120-125.
6. Bohn MC, Choi-Lundberg DL, Davidson BL, et al.: Adenovirusmediated transgene expression in nonhuman primate brain. Hum Gene Ther 1999, 10: 1175-1184.
7. Christenson SD, Lake KD, Ooboshi H, et al.: Adenovirusmediated gene transfer in vivo to cerebral blood vessels and perivascular tissue in mice. Stroke 1998, 29: 1411-1415.
8. Kullo IJ, Mozes G, Schwartz RS, et al.: Enhanced endotheliumdependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries. Hypertension 1997, 30: 314-320.
9. Lawrence MS, McLaughlin JR, Sun GH, et al.: Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke. J Cereb Blood Flow Metab 1997, 17: 740-744.
10. Huang Q, Vonsattel JP, Schaffer PA, et al.: Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: a light and electron microscopic study. Exp Neurol 1992, 115: 303-316.
11. Bender MA, Gelinas RE, Miller AD: A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells. Mol Cell Biol 1989, 9: 1426-1434.
12. Davidson BL, Stein CS, Heth JA, et al.: Recombinant adenoassociated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc Natl Acad Sci U S A 2000, 97: 3428-3432.
13. Alisky JM, Hughes SM, Sauter SL, et al.: Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors. Neuroreport 2000, 11: 2669-2673.
14. Duan D, Yue Y, Yan Z, et al.: A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation. Nat Med 2000, 6: 595-598.
15. Parks RJ, Bramson JL: Adenoviral vectors: prospects for gene delivery to the central nervous system. Gene Ther 1999, 6: 1349-1350.
16. Lawrence MS, Foellmer HG, Elsworth JD, et al.: Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus. Gene Ther 1999, 6: 1368-1379.
17. Schiedner G, Morral N, Parks RJ, et al.: Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat Genet 1998, 18: 180-183.
18. Toyoda K, Andresen JJ, Zabner J, et al.: Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessels in vitro and in vivo. Gene Ther 2000, 7: 1284-1291.
19. Yang K, Clifton GL, Hayes RL: Gene therapy for central nervous system injury: the use of cationic liposomes: an invited review. J Neurotrauma 1997, 14: 281-297.
20. Felgner PL: Improvements in cationic liposomes for in vivo gene transfer. Hum Gene Ther 1996, 7: 1791-1793.
21. Peng KW, Russell SJ: Viral vector targeting. Curr Opin Biotechnol 1999, 10: 454-457.
22. Wickham TJ: Targeting adenovirus. Gene Ther 2000, 7: 110-114.
23. Zoldhelyi P, McNatt J, Shelat HS, et al.: Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor. Circulation 2000, 101: 289-295.
24. Nishida T, Ueno H, Atsuchi N, et al.: Adenovirus-mediated local expression of human tissue factor pathway inhibitor eliminates shear stress-induced recurrent thrombosis in the injured carotid artery of the rabbit. Circ Res 1999, 84: 1446-1452.
25. Mozes G, Mohacsi T, Gloviczki P, et al.: Adenovirus-mediated gene transfer of macrophage colony stimulating factor to the arterial wall in vivo. Arterioscler Thromb Vasc Biol 1998, 18: 1157-1163.
26. Channon KM, Qian H, Neplioueva V, et al.: In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterolfed rabbits. Circulation 1998, 98: 1905-1911.
27. Ueno H, Yamamoto H, Ito S, et al.: Adenovirus-mediated transfer of a dominant-negative H-ras suppresses neointimal formation in balloon-injured arteries in vivo. Arterioscler Thromb Vasc Biol 1997, 17: 898-904.
28. Sato J, Mohacsi T, Noel A, et al.: In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endotheliumdependent relaxations. Stroke 2000, 31: 968-975.
29. Lund DD, Faraci FM, Miller FJ Jr, et al.: Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits. Circulation 2000, 101: 1027-1033.
30. Kibbe M, Billiar T, Tzeng E: Nitric oxide synthase gene transfer to the vessel wall. Curr Opin Nephrol Hypertens 1999, 8: 75-81.
31. Chen AF, O'Brien T, Tsutsui M, et al.: Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery. Circ Res 1997, 80: 327-335.
32. Rios CD, Ooboshi H, Piegors D, et al.: Adenovirus-mediated gene transfer to normal and atherosclerotic arteries. A novel approach. Arterioscler Thromb Vasc Biol 1995, 15: 2241-2245.
33. Ooboshi H, Welsh MJ, Rios CD, et al.: Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circ Res 1995, 77: 7-13.
34. Muhonen MG, Ooboshi H, Welsh MJ, et al.: Gene transfer to cerebral blood vessels after subarachnoid hemorrhage. Stroke 1997, 28: 822-828.
35. Ooboshi H, Ibayashi S, Heistad DD, et al.: Adenovirusmediated gene transfer to cerebral circulation. Mech Ageing Dev 2000, 116: 95-101.
36. Driesse MJ, Kros JM, Avezaat CJ, et al.: Distribution of recombinant adenovirus in the cerebrospinal fluid of nonhuman primates. Hum Gene Ther 1999, 10: 2347-2354.
37. Lin KF, Chao J, Chao L: Atrial natriuretic peptide gene delivery reduces stroke-induced mortality rate in Dahl salt-sensitive rats. Hypertension 1999, 33: 219-224.
38. Zhang JJ, Chao L, Chao J: Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats. Stroke 1999, 30: 1925-1931.
39. Abe K, Setoguchi Y, Hayashi T, et al.: In vivo adenovirusmediated gene transfer and the expression in ischemic and reperfused rat brain. Brain Res 1997, 763: 191-201.
40. Betz AL, Yang GY, Davidson BL: Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J Cereb Blood Flow Metab 1995, 15: 547-551.
41. Kitagawa H, Sasaki C, Sakai K, et al.: Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 1999, 19: 1336-1344.
42. Raymond J, Desfaits AC, Roy D: Fibrinogen and vascular smooth muscle cell grafts promote healing of experimental aneurysms treated by embolization. Stroke 1999, 30: 1657-1664.
43. Kimura H, Sakata Y, Hamada H, et al.: In vivo retention of endothelial cells adenovirally transduced with tissue-type plasminogen activator and seeded onto expanded polytetrafluoroethylene. J Vasc Surg 2000, 32: 353-363.
44. Toyoda K, Faraci FM, Watanabe J, et al.: Gene transfer of CGRP prevents vasoconstriction after subarachnoid hemorrhage. Circ Res 2000, 87: 818-824.
45. Sobey CG, Quan L: Impaired cerebral vasodilator responses to NO and PDE V inhibition after subarachnoid hemorrhage. Am J Physiol 1999, 277: H1718-H1724.
46. Stoodley M, Weihl CC, Zhang ZD, et al.: Effect of adenovirusmediated nitric oxide synthase gene transfer on vasospasm after experimental subarachnoid hemorrhage. Neurosurgery 2000, 46: 1193-1202.
47. Onoue H, Tsutsui M, Smith L, et al.: Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage. Stroke 1998, 29: 1959-1965.
48. Ay H, Ay I, Koroshetz WJ, et al.: Potential usefulness of basic fibroblast growth factor as a treatment for stroke. Cerebrovasc Dis 1999, 9: 131-135.
49. Hayashi T, Abe K, Itoyama Y: Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia. J Cereb Blood Flow Metab 1998, 18: 887-895.
50. Yenari MA, Fink SL, Sun GH, et al.: Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. Ann Neurol 1998, 44: 584-591.