메뉴 건너뛰기




Volumn 479, Issue 1-3, 2003, Pages 269-281

Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney

Author keywords

Drug disposition; Kidney; Localization; Nucleoside analog; Nucleoside transporter; Renal cancer

Indexed keywords

ADENOSINE DEOXYADENOSINE; CARRIER PROTEIN; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 2; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 3; CYTARABINE; DIDANOSINE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; GEMCITABINE; NUCLEOSIDE; NUCLEOSIDE ANALOG; RIBAVIRIN; SOLUTE CARRIER 28A1; SOLUTE CARRIER 28A2; SOLUTE CARRIER 28A3; SOLUTE CARRIER 29A1; SOLUTE CARRIER 29A2; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 0242637653     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.08.076     Document Type: Article
Times cited : (73)

References (81)
  • 4
    • 0037165658 scopus 로고    scopus 로고
    • PKC regulation of the human equilibrative nucleoside transporter, hENT1
    • Coe I., Zhang Y., McKenzie T., Naydenova Z. PKC regulation of the human equilibrative nucleoside transporter, hENT1. FEBS Lett. 517:2002;201-205.
    • (2002) FEBS Lett. , vol.517 , pp. 201-205
    • Coe, I.1    Zhang, Y.2    McKenzie, T.3    Naydenova, Z.4
  • 5
    • 0032451702 scopus 로고    scopus 로고
    • Stable expression of a recombinant sodium-dependent, pyrimidine- selective nucleoside transporter (CNT1) in a transport-deficient mouse leukemia cell line
    • Crawford C.R., Cass C.E., Young J.D., Belt J.A. Stable expression of a recombinant sodium-dependent, pyrimidine-selective nucleoside transporter (CNT1) in a transport-deficient mouse leukemia cell line. Biochem. Cell. Biol. 76:1998;843-851.
    • (1998) Biochem. Cell. Biol. , vol.76 , pp. 843-851
    • Crawford, C.R.1    Cass, C.E.2    Young, J.D.3    Belt, J.A.4
  • 6
    • 0032570584 scopus 로고    scopus 로고
    • Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line
    • Crawford C.R., Patel D.H., Naeve C., Belt J.A. Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line. J. Biol. Chem. 273:1998;5288-5293.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5288-5293
    • Crawford, C.R.1    Patel, D.H.2    Naeve, C.3    Belt, J.A.4
  • 9
    • 0033840257 scopus 로고    scopus 로고
    • Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes
    • Dresser M.J., Gerstin K.M., Gray A.T., Loo D.D., Giacomini K.M. Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes. Drug Metab. Dispos. 28:2000;1135-1140.
    • (2000) Drug Metab. Dispos. , vol.28 , pp. 1135-1140
    • Dresser, M.J.1    Gerstin, K.M.2    Gray, A.T.3    Loo, D.D.4    Giacomini, K.M.5
  • 10
    • 0030015533 scopus 로고    scopus 로고
    • Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells
    • Fang X., Parkinson F.E., Mowles D.A., Young J.D., Cass C.E. Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells. Biochem. J. 317(Pt. 2):1996;457-465.
    • (1996) Biochem. J. , vol.317 , Issue.2 PART , pp. 457-465
    • Fang, X.1    Parkinson, F.E.2    Mowles, D.A.3    Young, J.D.4    Cass, C.E.5
  • 11
    • 0032032381 scopus 로고    scopus 로고
    • +-dependent nucleoside transport in liver: Two different isoforms from the same gene family are expressed in liver cells
    • +-dependent nucleoside transport in liver: two different isoforms from the same gene family are expressed in liver cells. Biochem. J. 330:1998;997-1001.
    • (1998) Biochem. J. , vol.330 , pp. 997-1001
    • Felipe, A.1    Valdes, R.2    Santo, B.3    Lloberas, J.4    Casado, J.5    Pastor-Anglada, M.6
  • 12
    • 0035033488 scopus 로고    scopus 로고
    • Uric acid nephrolithiasis associated with interferon and ribavirin treatment of hepatitis C
    • Fontana R.J. Uric acid nephrolithiasis associated with interferon and ribavirin treatment of hepatitis C. Dig. Dis. Sci. 46:2001;920-924.
    • (2001) Dig. Dis. Sci. , vol.46 , pp. 920-924
    • Fontana, R.J.1
  • 14
    • 0036064248 scopus 로고    scopus 로고
    • Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT
    • Gerstin K.M., Dresser M.J., Giacomini K.M. Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT. Am. J. Physiol., Renal. Physiol. 283:2002;F344-F349.
    • (2002) Am. J. Physiol., Renal. Physiol. , vol.283
    • Gerstin, K.M.1    Dresser, M.J.2    Giacomini, K.M.3
  • 20
    • 0031439882 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a nitrobenzylthioinosine- insensitive (ei) equilibrative nucleoside transporter from human placenta
    • Griffiths M., Yao S.Y., Abidi F., Phillips S.E., Cass C.E., Young J.D., Baldwin S.A. Molecular cloning and characterization of a nitrobenzylthioinosine- insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem. J. 328:1997;739-743.
    • (1997) Biochem. J. , vol.328 , pp. 739-743
    • Griffiths, M.1    Yao, S.Y.2    Abidi, F.3    Phillips, S.E.4    Cass, C.E.5    Young, J.D.6    Baldwin, S.A.7
  • 21
    • 0027299916 scopus 로고
    • + nucleoside transport in brush border membrane vesicles from human kidney
    • + nucleoside transport in brush border membrane vesicles from human kidney. Biochim. Biophys. Acta. 1149:1993;202-208.
    • (1993) Biochim. Biophys. Acta , vol.1149 , pp. 202-208
    • Gutierrez, M.M.1    Giacomini, K.M.2
  • 22
    • 0028126585 scopus 로고
    • Expression of a human renal sodium nucleoside cotransporter in Xenopus laevis oocytes
    • Gutierrez M.M., Giacomini K.M. Expression of a human renal sodium nucleoside cotransporter in Xenopus laevis oocytes. Biochem. Pharmacol. 48:1994;2251-2253.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 2251-2253
    • Gutierrez, M.M.1    Giacomini, K.M.2
  • 25
    • 0034014541 scopus 로고    scopus 로고
    • Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: Species differences and transporter subtype selectivity
    • Hammond J.R. Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity. Naunyn-Schmiedeberg's Arch. Pharmacol. 361:2000;373-382.
    • (2000) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.361 , pp. 373-382
    • Hammond, J.R.1
  • 26
    • 0025313803 scopus 로고
    • Pharmacokinetics of 2′,3′-dideoxyadenosine and 2′,3′-dideoxyinosine in patients with severe human immunodeficiency virus infection
    • Hartman N.R., Yarchoan R., Pluda J.M., Thomas R.V., Marczyk K.S., Broder S., Johns D.G. Pharmacokinetics of 2′,3′-dideoxyadenosine and 2′,3′-dideoxyinosine in patients with severe human immunodeficiency virus infection. Clin. Pharmacol. Ther. 47:1990;647-654.
    • (1990) Clin. Pharmacol. Ther. , vol.47 , pp. 647-654
    • Hartman, N.R.1    Yarchoan, R.2    Pluda, J.M.3    Thomas, R.V.4    Marczyk, K.S.5    Broder, S.6    Johns, D.G.7
  • 27
    • 0028362987 scopus 로고
    • Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
    • Huang Q.Q., Yao S.Y., Ritzel M.W., Paterson A.R., Cass C.E., Young J.D. Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J. Biol. Chem. 269:1994;17757-17760.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17757-17760
    • Huang, Q.Q.1    Yao, S.Y.2    Ritzel, M.W.3    Paterson, A.R.4    Cass, C.E.5    Young, J.D.6
  • 28
    • 0034995844 scopus 로고    scopus 로고
    • The ENT family of eukaryote nucleoside and nucleobase transporters: Recent advances in the investigation of structure/function relationships and the identification of novel isoforms
    • Hyde R.J., Cass C.E., Young J.D., Baldwin S.A. The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol. Membr. Biol. 18:2001;53-63.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 53-63
    • Hyde, R.J.1    Cass, C.E.2    Young, J.D.3    Baldwin, S.A.4
  • 30
    • 0019955093 scopus 로고
    • Renal handling of 2′-deoxyadenosine and adenosine in humans and mice
    • Kuttesch J.F. Jr., Nelson J.A. Renal handling of 2′-deoxyadenosine and adenosine in humans and mice. Cancer Chemother. Pharmacol. 8:1982;221-229.
    • (1982) Cancer Chemother. Pharmacol. , vol.8 , pp. 221-229
    • Kuttesch Jr., J.F.1    Nelson, J.A.2
  • 31
    • 0037020070 scopus 로고    scopus 로고
    • Simultaneous expression of hCNT1-CFP and hENT1-YFP in Mardin-Darby canine kidney (MDCK) cells: Localization and vectorial transport studies
    • Lai Y., Bakken A.D., Unadkat J.D. Simultaneous expression of hCNT1-CFP and hENT1-YFP in Mardin-Darby canine kidney (MDCK) cells: localization and vectorial transport studies. J. Biol. Chem. 277(40):2002;37711-37717.
    • (2002) J. Biol. Chem. , vol.277 , Issue.40 , pp. 37711-37717
    • Lai, Y.1    Bakken, A.D.2    Unadkat, J.D.3
  • 34
    • 0021201229 scopus 로고
    • Sodium gradient-energized concentrative transport of adenosine in renal brush border vesicles
    • Le Hir M., Dubach U.C. Sodium gradient-energized concentrative transport of adenosine in renal brush border vesicles. Pflugers Arch. 401:1984;58-63.
    • (1984) Pflugers Arch. , vol.401 , pp. 58-63
    • Le Hir, M.1    Dubach, U.C.2
  • 37
    • 0034666069 scopus 로고    scopus 로고
    • Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes
    • Lostao M.P., Mata J.F., Larrayoz I.M., Inzillo S.M., Casado F.J., Pastor-Anglada M. Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes. FEBS Lett. 481:2000;137-140.
    • (2000) FEBS Lett. , vol.481 , pp. 137-140
    • Lostao, M.P.1    Mata, J.F.2    Larrayoz, I.M.3    Inzillo, S.M.4    Casado, F.J.5    Pastor-Anglada, M.6
  • 38
    • 0034017591 scopus 로고    scopus 로고
    • Human intestinal es nucleoside transporter: Molecular characterization and nucleoside inhibitory profiles
    • Lum P.Y., Ngo L.Y., Bakken A.H., Unadkat J.D. Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles. Cancer Chemother. Pharmacol. 45:2000;273-278.
    • (2000) Cancer Chemother. Pharmacol. , vol.45 , pp. 273-278
    • Lum, P.Y.1    Ngo, L.Y.2    Bakken, A.H.3    Unadkat, J.D.4
  • 39
    • 0032188825 scopus 로고    scopus 로고
    • Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
    • Mackey J.R., Mani R.S., Selner M., Mowles D., Young J.D., Belt J.A., Crawford C.R., Cass C.E. Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. Cancer Res. 58:1998;4349-4357.
    • (1998) Cancer Res. , vol.58 , pp. 4349-4357
    • Mackey, J.R.1    Mani, R.S.2    Selner, M.3    Mowles, D.4    Young, J.D.5    Belt, J.A.6    Crawford, C.R.7    Cass, C.E.8
  • 40
    • 0033520708 scopus 로고    scopus 로고
    • Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters
    • Mackey J.R., Yao S.Y., Smith K.M., Karpinski E., Baldwin S.A., Cass C.E., Young J.D. Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. J. Natl. Cancer Inst. 91:1999;1876-1881.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1876-1881
    • Mackey, J.R.1    Yao, S.Y.2    Smith, K.M.3    Karpinski, E.4    Baldwin, S.A.5    Cass, C.E.6    Young, J.D.7
  • 42
    • 0035035911 scopus 로고    scopus 로고
    • Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line
    • Mangravite L.M., Lipschutz J.H., Mostov K.E., Giacomini K.M. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am. J. Physiol., Renal Physiol. 280:2001;F879-F885.
    • (2001) Am. J. Physiol., Renal Physiol. , vol.280
    • Mangravite, L.M.1    Lipschutz, J.H.2    Mostov, K.E.3    Giacomini, K.M.4
  • 43
    • 0037404222 scopus 로고    scopus 로고
    • Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells
    • Mangravite L.M., Xiao G., Giacomini K.M. Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. Am. J. Physiol., Renal Physiol. 284:2003;F902-F910.
    • (2003) Am. J. Physiol., Renal Physiol. , vol.284
    • Mangravite, L.M.1    Xiao, G.2    Giacomini, K.M.3
  • 44
    • 0034984732 scopus 로고    scopus 로고
    • Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5′-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug
    • Mata J.F., Garcia-Manteiga J.M., Lostao M.P., Fernandez-Veledo S., Guillen-Gomez E., Larrayoz I.M., Lloberas J., Casado F.J., Pastor-Anglada M. Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5′-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug. Mol. Pharmacol. 59:2001;1542-1548.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1542-1548
    • Mata, J.F.1    Garcia-Manteiga, J.M.2    Lostao, M.P.3    Fernandez-Veledo, S.4    Guillen-Gomez, E.5    Larrayoz, I.M.6    Lloberas, J.7    Casado, F.J.8    Pastor-Anglada, M.9
  • 47
    • 0037155786 scopus 로고    scopus 로고
    • Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells
    • Parodi J., Flores C., Aguayo C., Rudolph M.I., Casanello P., Sobrevia L. Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells. Circ. Res. 90:2002;570-577.
    • (2002) Circ. Res. , vol.90 , pp. 570-577
    • Parodi, J.1    Flores, C.2    Aguayo, C.3    Rudolph, M.I.4    Casanello, P.5    Sobrevia, L.6
  • 48
    • 0024363993 scopus 로고
    • Pharmacokinetics of ribavirin and urinary excretion of the major metabolite 1,2,4-triazole-3-carboxamide in normal volunteers
    • Paroni R., Del Puppo M., Borghi C., Sirtori C.R., Galli Kienle M. Pharmacokinetics of ribavirin and urinary excretion of the major metabolite 1,2,4-triazole-3-carboxamide in normal volunteers. Int. J. Clin. Pharmacol. Ther. Toxicol. 27:1989;302-307.
    • (1989) Int. J. Clin. Pharmacol. Ther. Toxicol. , vol.27 , pp. 302-307
    • Paroni, R.1    Del Puppo, M.2    Borghi, C.3    Sirtori, C.R.4    Galli Kienle, M.5
  • 55
    • 0030813149 scopus 로고    scopus 로고
    • Transient expression of a purine-selective nucleoside transporter (SPNTint) in a human cell line (HeLa)
    • Schaner M.E., Wang J., Zevin S., Gerstin K.M., Giacomini K.M. Transient expression of a purine-selective nucleoside transporter (SPNTint) in a human cell line (HeLa). Pharm. Res. 14:1997;1316-1321.
    • (1997) Pharm. Res. , vol.14 , pp. 1316-1321
    • Schaner, M.E.1    Wang, J.2    Zevin, S.3    Gerstin, K.M.4    Giacomini, K.M.5
  • 56
    • 0037022199 scopus 로고    scopus 로고
    • A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine
    • SenGupta D.J., Lum P.Y., Lai Y., Shubochkina E., Bakken A.H., Schneider G., Unadkat J.D. A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine. Biochemistry. 41:2002;1512-1519.
    • (2002) Biochemistry , vol.41 , pp. 1512-1519
    • SenGupta, D.J.1    Lum, P.Y.2    Lai, Y.3    Shubochkina, E.4    Bakken, A.H.5    Schneider, G.6    Unadkat, J.D.7
  • 57
    • 0018176254 scopus 로고
    • Cytosine arabinoside induced gastrointestinal toxic alterations in sequential chemotherapeutic protocols: A clinical-pathologic study of 33 patients
    • Slavin R.E., Dias M.A., Saral R. Cytosine arabinoside induced gastrointestinal toxic alterations in sequential chemotherapeutic protocols: a clinical-pathologic study of 33 patients. Cancer. 42:1978;1747-1759.
    • (1978) Cancer , vol.42 , pp. 1747-1759
    • Slavin, R.E.1    Dias, M.A.2    Saral, R.3
  • 59
    • 0026024245 scopus 로고
    • Adenosine receptors and signaling in the kidney
    • Spielman W.S., Arend L.J. Adenosine receptors and signaling in the kidney. Hypertension. 17:1991;117-130.
    • (1991) Hypertension , vol.17 , pp. 117-130
    • Spielman, W.S.1    Arend, L.J.2
  • 61
    • 0032555498 scopus 로고    scopus 로고
    • Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs
    • Sundaram M., Yao S.Y., Ng A.M., Griffiths M., Cass C.E., Baldwin S.A., Young J.D. Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs. J. Biol. Chem. 273:1998;21519-21525.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21519-21525
    • Sundaram, M.1    Yao, S.Y.2    Ng, A.M.3    Griffiths, M.4    Cass, C.E.5    Baldwin, S.A.6    Young, J.D.7
  • 62
    • 0035976921 scopus 로고    scopus 로고
    • Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs
    • Sundaram M., Yao S.Y., Ingram J.C., Berry Z.A., Abidi F., Cass C.E., Baldwin S.A., Young J.D. Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs. J. Biol. Chem. 276:2001;45270-45275.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45270-45275
    • Sundaram, M.1    Yao, S.Y.2    Ingram, J.C.3    Berry, Z.A.4    Abidi, F.5    Cass, C.E.6    Baldwin, S.A.7    Young, J.D.8
  • 63
    • 0035838493 scopus 로고    scopus 로고
    • Equilibrative nucleoside transporters: Mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins
    • Sundaram M., Yao S.Y., Ng A.M., Cass C.E., Baldwin S.A., Young J.D. Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins. Biochemistry. 40:2001;8146-8151.
    • (2001) Biochemistry , vol.40 , pp. 8146-8151
    • Sundaram, M.1    Yao, S.Y.2    Ng, A.M.3    Cass, C.E.4    Baldwin, S.A.5    Young, J.D.6
  • 64
    • 0036384221 scopus 로고    scopus 로고
    • Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs
    • Valdes R., Casado F.J., Pastor-Anglada M. Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs. Biochem. Biophys. Res. Commun. 296:2002;575-579.
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 575-579
    • Valdes, R.1    Casado, F.J.2    Pastor-Anglada, M.3
  • 65
    • 0033118410 scopus 로고    scopus 로고
    • Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q)
    • Vickers M.F., Mani R.S., Sundaram M., Hogue D.L., Young J.D., Baldwin S.A., Cass C.E. Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q). Biochem. J. 339:1999;21-32.
    • (1999) Biochem. J. , vol.339 , pp. 21-32
    • Vickers, M.F.1    Mani, R.S.2    Sundaram, M.3    Hogue, D.L.4    Young, J.D.5    Baldwin, S.A.6    Cass, C.E.7
  • 66
    • 0035010526 scopus 로고    scopus 로고
    • Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae
    • Vickers M.F., Young J.D., Baldwin S.A., Ellison M.J., Cass C.E. Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae. Mol. Membr. Biol. 18:2001;73-79.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 73-79
    • Vickers, M.F.1    Young, J.D.2    Baldwin, S.A.3    Ellison, M.J.4    Cass, C.E.5
  • 67
    • 0347997273 scopus 로고    scopus 로고
    • Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae
    • Vickers M.F., Kumar R., Visser F., Zhang J., Charania J., Raborn R.T., Baldwin S.A., Young J.D., Cass C.E. Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae. Biochem. Cell Biol. 80:2002;639-644.
    • (2002) Biochem. Cell Biol. , vol.80 , pp. 639-644
    • Vickers, M.F.1    Kumar, R.2    Visser, F.3    Zhang, J.4    Charania, J.5    Raborn, R.T.6    Baldwin, S.A.7    Young, J.D.8    Cass, C.E.9
  • 68
    • 0030663285 scopus 로고    scopus 로고
    • + dependent nucleoside transporters
    • + dependent nucleoside transporters. J. Biol. Chem. 272:1997;28845-28848.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28845-28848
    • Wang, J.1    Giacomini, K.M.2
  • 73
    • 0034708596 scopus 로고    scopus 로고
    • Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine
    • Ward J.L., Sherali A., Mo Z.P., Tse C.M. Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine. J. Biol. Chem. 275:2000;8375-8381.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8375-8381
    • Ward, J.L.1    Sherali, A.2    Mo, Z.P.3    Tse, C.M.4
  • 74
    • 0024993096 scopus 로고
    • + dependent purine and pyrimidine nucleoside transporters in bovine outer renal cortex brush-border-membrane vesicles
    • + dependent purine and pyrimidine nucleoside transporters in bovine outer renal cortex brush-border-membrane vesicles. Biochem. Soc. Trans. 18:1990;684-685.
    • (1990) Biochem. Soc. Trans. , vol.18 , pp. 684-685
    • Williams, T.C.1    Jarvis, S.M.2
  • 75
    • 0025981264 scopus 로고
    • Multiple sodium-dependent nucleoside transport systems in bovine renal brush-border membrane vesicles
    • Williams T.C., Jarvis S.M. Multiple sodium-dependent nucleoside transport systems in bovine renal brush-border membrane vesicles. Biochem. J. 274:1991;27-33.
    • (1991) Biochem. J. , vol.274 , pp. 27-33
    • Williams, T.C.1    Jarvis, S.M.2
  • 76
    • 0024430047 scopus 로고
    • Characterization of sodium-dependent and sodium-independent nucleoside transport systems in rabbit brush-border and basolateral plasma-membrane vesicles from the renal outer cortex
    • Williams T.C., Doherty A.J., Griffith D.A., Jarvis S.M. Characterization of sodium-dependent and sodium-independent nucleoside transport systems in rabbit brush-border and basolateral plasma-membrane vesicles from the renal outer cortex. Biochem. J. 264:1989;223-231.
    • (1989) Biochem. J. , vol.264 , pp. 223-231
    • Williams, T.C.1    Doherty, A.J.2    Griffith, D.A.3    Jarvis, S.M.4
  • 77
    • 0036180689 scopus 로고    scopus 로고
    • Cytotoxicity of 2-chlorodeoxyadenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: Significance of cellular nucleoside transporter content
    • Wright A.M., Paterson A.R., Sowa B., Akabutu J.J., Grundy P.E., Gati W.P. Cytotoxicity of 2-chlorodeoxyadenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: significance of cellular nucleoside transporter content. Br. J. Haematol. 116:2002;528-537.
    • (2002) Br. J. Haematol. , vol.116 , pp. 528-537
    • Wright, A.M.1    Paterson, A.R.2    Sowa, B.3    Akabutu, J.J.4    Grundy, P.E.5    Gati, W.P.6
  • 78
    • 0026794356 scopus 로고
    • Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides
    • Wu X., Yuan G., Brett C.M., Hui A.C., Giacomini K.M. Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides. J. Biol. Chem. 267:1992;8813-8818.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8813-8818
    • Wu, X.1    Yuan, G.2    Brett, C.M.3    Hui, A.C.4    Giacomini, K.M.5
  • 79
    • 0030707865 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues
    • Yao S.Y., Ng A.M., Muzyka W.R., Griffiths M., Cass C.E., Baldwin S.A., Young J.D. Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues. J. Biol. Chem. 272:1997;28423-28430.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28423-28430
    • Yao, S.Y.1    Ng, A.M.2    Muzyka, W.R.3    Griffiths, M.4    Cass, C.E.5    Baldwin, S.A.6    Young, J.D.7
  • 80
    • 0034918036 scopus 로고    scopus 로고
    • Transport of antiviral 3′-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes
    • Yao S.Y., Ng A.M., Sundaram M., Cass C.E., Baldwin S.A., Young J.D. Transport of antiviral 3′-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes. Mol. Membr. Biol. 18:2001;161-167.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 161-167
    • Yao, S.Y.1    Ng, A.M.2    Sundaram, M.3    Cass, C.E.4    Baldwin, S.A.5    Young, J.D.6
  • 81
    • 0037067704 scopus 로고    scopus 로고
    • Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation
    • Yao S.Y., Ng A.M., Vickers M.F., Sundaram M., Cass C.E., Baldwin S.A., Young J.D. Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation. J. Biol. Chem. 277:2002;24938-24948.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24938-24948
    • Yao, S.Y.1    Ng, A.M.2    Vickers, M.F.3    Sundaram, M.4    Cass, C.E.5    Baldwin, S.A.6    Young, J.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.