Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT

American Journal of Physiology - Renal Physiology

Volumn 283, Issue 2 52-2, 2002, Pages

  Gerstin, Karin M ^a   Dresser, Mark J ^a   Giacomini, Kathleen M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine; Concentrative; Guanosine; Sodium dependent; Two electrode voltage clamp

Indexed keywords

2',3' DIDEOXYADENOSINE; ADENOSINE; CARRIER PROTEIN; CLADRIBINE; GUANOSINE; INOSINE; NUCLEIC ACID BASE; NUCLEOSIDE; PURINE NUCLEOSIDE; SODIUM DEPENDENT PURINE SELECTIVE NUCLEOSIDE TRANSPORTER; UNCLASSIFIED DRUG; URIDINE; URIDINE DERIVATIVE; VIDARABINE;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME SPECIFICITY; HUMAN; MEMBRANE CURRENT; NONHUMAN; NUCLEOSIDE TRANSPORT; OOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SPECIES DIFFERENCE; VOLTAGE CLAMP; XENOPUS LAEVIS;

EID: 0036064248     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00274.2001     Document Type: Article

References (32)

1. +/glucose cotransporter cloned from rabbit small intestine
2. Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter
3. Electrophysiological analysis of the substrate selectivity of a sodium-coupled transporter (rCNT1) expressed in Xenopus laevis oocytes
4. Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
5. +-dependent nucleoside transporter from rabbit intestine
6. Expression of a renal Na(+)-nucleoside cotransport system (N2) in Xenopus laevis oocytes
7. Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
8. + channels radically alters activation and inactivation
9. Differentiation of substrate and nonsubstrate inhibitors of the high-affinity sodium-dependent glutamate transporters
10. +-dependent uridine transport in rat renal brush-border membrane vesicles
11. Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2
12. Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes
13. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line
14. +/nucleoside cotransporter from pig kidney, pkCNT1
15. +/dicarboxylate cotransporter
16. Cloning, genomic organization and chromosomal localization of the gene encoding the murine sodium-dependent, purine-selective, concentrative nucleoside transporter (CNT2)
17. +-nucleoside transporters
18. Receptors for purines and pyrimidines
19. +-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)
20. +-nucleoside cotransporter (hCNT1)
21. Transient expression of a purine-selective nucleoside transporter (SPNTint) in a human cell line (HeLa)
22. +-dependent nucleoside transporter (hSPNT1) in a mammalian expression system
23. Evidence for alternative splicing of ecto-ATPase associated with termination of purinergic transmission
24. Ecto-nucleotidases terminate purinergic signaling in the cochlear endolymphatic compartment
25. +-dependent nucleoside transporters
26. Functional and molecular characteristics of Na(+)-dependent nucleoside transporters
27. +-dependent purine nucleoside transporter from human kidney: Cloning and functional characterization
28. Characterization of sodium-dependent and sodium-independent nucleoside transport systems in rabbit brush-border and basolateral plasma-membrane vesicles from the renal outer cortex
29. Multiple sodium-dependent nucleoside transport systems in bovine renal brush-border membrane vesicles
30. A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans
31. Steady-state binding of adenine nucleotides ATP, ADP and AMP to rat liver and adipose plasma membranes