Crystal structure of cathepsin X: A flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease

Structure

Volumn 8, Issue 3, 2000, Pages 305-313

  Gunčar, Gregor ^a   Klemenčič, Ivica ^a   Turk, Boris ^a   Turk, Vito ^a   Karaoglanovic Carmona, Adriana ^b   Juliano, Luiz ^b   Turk, Dušan ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Alzheimer's disease; Carboxypeptidase; Cathepsin B; Cathepsin X; Papain like cysteine protease

Indexed keywords

CATHEPSIN; HISTIDINE; PEPTIDASE; PROTEIN INHIBITOR; PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE;

MAMMALIA;

EID: 0242599721     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00108-8     Document Type: Article

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