E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 9, 1997, Pages 1789-1797

  Schaschke, Norbert ^a   Assfalg Machleidt, Irmgard ^b   Machleidt, Werner ^b   Turk, Dushan ^c   Moroder, Luis ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CYSTEINE PROTEINASE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY;

CATHEPSIN B; CRYSTALLOGRAPHY, X-RAY; CYSTEINE PROTEINASE INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LEUCINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SALTS; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STEREOISOMERISM;

EID: 0030758945     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00105-3     Document Type: Article

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