Rapidly activated microglial cells in the preoptic area may play a role in the generation of hyperthermia following occlusion of the middle cerebral artery in the rat

Experimental Brain Research

Volumn 153, Issue 1, 2003, Pages 84-91

  Ábrahám, Hajnalka ^a,b,c   Somogyvári Vigh, Anikó ^a,b   Maderdrut, Jerome L ^a,b   Vigh, Sándor ^b   Arimura, Akira ^a,b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY   (United States)

^c UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Fever; Glial cells; Hypothalamus; Ischemia; Stroke

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CONTROLLED STUDY; FEVER; HYPERTHERMIA; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; RAT; RAT STRAIN; REPERFUSION; THERMOREGULATION;

ANIMALS; ASTROCYTES; BODY TEMPERATURE; FEVER; GLIAL FIBRILLARY ACIDIC PROTEIN; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN-1; MALE; MICROGLIA; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0242329369     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-003-1572-8     Document Type: Article

References (65)

1. Abraham H, Lazar Gy (2000) Early microglial reaction following mild forebrain ischemia induced by common carotid artery occlusion in rats. Brain Res 862:63-73
2. Abraham H, Losonczy A, Czeh G, Lazar Gy (2001) Rapid activation of microglial cells by hypoxia, kainic acid, and potassium ions in slice preparations of the rat hippocampus. Brain Res 906:115-126
3. Abraham H, Somogyvari-Vigh A, Maderdrut JL, Vigh S, Arimura A (2002) Filament size influences temperature changes and brain damage following middle cerebral artery occlusion in rats. Exp Brain Res 142:131-138
4. Alheim K, Chai Z, Fantuzzi G, Hasanvan H, Malinowsky D, Di Santo E, Ghezzi P, Dinarello CA, Bartfai T (1997) Hyperresponsive febrile reactions to interleukin (IL)-1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice. Proc Natl Acad Sci USA 94:2681-2686
5. Ambach G, Kivovics P, Palkovits M (1978) The arterial and venous blood supply of the preoptic region in the rat. Acta Morphol Acad Sci Hung 26:21-41
6. Andrews RJ (1991) Transhemispheric diaschisis. A review and comment. Stroke 22:943-949
7. Azzimondi G, Bassein L, Nonino F, Fiorani L, Vignatelli L, Re G, D'Alessandro R (1995) Fever in acute stroke worsens prognosis. A prospective study. Stroke 26:2040-2043
8. Banati RB, Graeber MB (1994) Surveillance, intervention and cytotoxicity: Is there a protective role of microglia? Dev Neurosci 16:114-127
9. Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472-476
10. Blatteis CM, Sehic E (1998) Cytokines and fever. Ann NY Acad Sci 840:608-618
11. Blatteis CM, Xin L, Quan N (1994) Neuromodulation of fever. A possible role for substance P. Ann NY Acad Sci 741:162-173
12. Boysen G, Christensen H (2001) Stroke severity determines body temperature in acute stroke. Stroke 32:413-417
13. Buchkremer-Ratzmann I, August M, Hagemann G, Witte OW (1998) Epileptiform discharges to extracellular stimuli in rat neocortical slices after photothrombotic infarction. J Neurol Sci 156:133-137
14. Chen H, Chopp M, Welch KM (1991) Effect of mild hyperthermia on the ischemic infarct volume after middle cerebral artery occlusion in the rat. Neurology 41:1133-1135
15. Davies CA, Loddick SA, Stroemer RP, Hunt J, Rothwell NJ (1998) An integrated analysis of the progression of cell responses induced by permanent focal middle cerebral artery occlusion in the rat. Exp Neurol 154:199-212
16. Davies CA, Loddick SA, Toulmond S, Stroemer RP, Hunt J, Rothwell NJ (1999) The progression and topographic distribution of interleukin-1-beta expression after permanent middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 19:87-89
17. Domann R, Hagemann G, Kraemer M, Freund HJ, Witte OW (1993) Electrophysiological changes in the surrounding brain tissue of photochemically induced cortical infarcts in the rat. Neurosci Lett 155:69-72
18. Garcia JH, Yoshida Y, Chen H, Li Y, Zhang ZG, Lian J, Chen S, Chopp M (1993) Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat. Am J Pathol 142:623-635
19. Gehrmann J, Kreutzberg GW (1995) Microglia in experimental neuropathology. In: Kettenmann H, Ransom BR (eds) Neuroglia. Oxford University Press, Oxford, pp 883-904
20. Gehrmann J, Bonnekoh P, Miyazawa T, Hossmann KA, Kreutzberg GW (1992) Immunocytochemical study of an early microglial activation in ischemia. J Cereb Blood Flow Metab 12:257-269
21. Gourmala NG, Limonta S, Bochelen D, Sauter A, Boddeke HW (1999) Localization of macrophage inflammatory protein: macrophage inflammatory protein-1 expression in rat brain after peripheral administration of lipopolysaccharide and focal cerebral ischemia. Neuroscience 88:1255-1266
22. Gregersen R, Lambertsen K, Finsen B (2000) Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab 20:53-65
23. Hellon RF (1972) Temperature-sensitive neurons in the brain stem: their responses to brain temperature at different ambient temperatures. Pflugers Arch 335:323-334
24. Herz RC, Kasbergen CM, Hillen B, Versteeg DH, Wildt DJ de (1998) Rat middle cerebral artery occlusion by an intraluminal thread compromises collateral blood flow. Brain Res 791:223-228
25. Hillhouse EW, Kida S, Iannotti F (1998) Middle cerebral artery occlusion in the rat causes a biphasic production of immunoreactive interleukin-1beta in the cerebral cortex. Neurosci Lett 249:177-179
26. Hori T, Shibata M, Nakashima T, Yamasaki M, Asami A, Asami T, Koga H (1988) Effects of interleukin-1 and arachidonate on the preoptic and anterior hypothalamic neurons. Brain Res Bull 20:75-82
27. + current in central neurons. Brain Res 614:352-356
28. Kato H, Walz W (2000) The initiation of microglial response. Brain Pathol 10:137-143
29. Kettenmann H, Hoppe D, Gottmann K, Banati R, Kreutzberg GW (1990) Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. J Neurosci Res 26:278-287
30. Kozak W, Zheng H, Conn CA, Soszynski D, Ploeg LH van der, Kluger MJ (1995) Thermal and behavioral effects of lipopolysaccharide and influenza in interleukin-1beta-deficient mice. Am J Physiol 269:R969-977
31. Lehrmann E, Christensen T, Zimmer J, Diemer NH, Finsen B (1997) Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol 386:461-476
32. Li F, Omae T, Fisher M (1999) Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats. Stroke 30:2464-2471
33. Long NC, Otterness I, Kunkel SL, Vander AJ, Kluger MJ (1990) Roles of interleukin 1 beta and tumor necrosis factor in lipopolysaccharide fever in rats. Am J Physiol 259:724-728
34. Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91
35. Mabuchi T, Kitagawa K, Ohtsuki T, Kuwabara K, Yagita Y, Yanagihara T, Hori M, Matsumoto M (2000) Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. Stroke 31:1735-1743
36. Memezawa H, Minamisawa H, Smith ML, Siesjo BK (1992) Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat. Exp Brain Res 89:67-78
37. Memezawa H, Zhao Q, Smith ML, Siesjo BK (1995) Hyperthermia nullifies the ameliorating effect of dizocilpine maleate (MK-801) in focal cerebral ischemia. Brain Res 670:48-52
38. Morioka T, Kalehua AN, Streit WJ (1991) The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia. J Cereb Blood Flow Metab 11:966-973
39. Morioka T, Kalehua AN, Streit WJ (1993) Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. J Comp Neurol 327:123-132
40. Myers RD, Lopez-Valpuesta FJ, Minano FJ, Wooten MH, Barwick VS, Wolpe SD (1994) Fever and feeding in the rat: actions of intrahypothalamic interleukin-6 compared with macrophage inflammatory protein-1 beta (MIP-1 beta). J Neurosci Res 39:31-37
41. Nallet H, MacKenzie ET, Roussel S (1999) The nature of penumbral depolarizations following focal cerebral ischemia in the rat. Brain Res 842:148-158
42. Nedergaard M, Cooper AJ, Goldman SA (1995) Gap junctions are required for the propagation of spreading depression. J Neurobiol 28:433-444
43. Neumann-Haefelin T, Witte OW (2000) Periinfarct and remote excitability changes after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 20:45-52
44. Neumann-Haefelin T, Hagemann G, Witte OW (1995) Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro. Neurosci Lett 193:101-104
45. Pearce B, Wilkin GP (1995) Eicosanoid, purine, and hormon receptors. In: Kettenmann H, Ransom BR (eds) Neuroglia. Oxford University Press, Oxford, pp 377-384
46. Reglodi D, Somogyvari-Vigh A, Maderdrut JL, Vigh S, Arimura A (2000) Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat. Exp Neurol 163:399-407
47. Reid KH, Marrannes R, Wauquier A (1988) Spreading depression and central nervous system pharmacology. J Pharmacol Methods 19:1-21
48. Reith J, Jorgensen HS, Pedersen PM, Nakayama H, Raaschou HO, Jeppesen LL, Olsen TS (1996) Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet 347:422-425
49. Rubin G, Levy EI, Scarrow AM, Firlik AD, Karakus A, Wechsler L, Jungreis CA, Yonas H (2000) Remote effects of acute ischemic stroke: a xenon CT cerebral blood flow study. Cerebrovasc Dis 10:221-228
50. Rupalla K, Allegrini PR, Sauer D, Wiessner C (1998) Time course of microglial activation and apoptosis in various brain regions after permanent focal cerebral ischemia in mice. Acta Neuropathol 96:172-178
51. Sairanen TR, Lindsberg PJ, Brenner M, Siren AL (1997) Global forebrain ischemia results in differential cellular expression of interleukin-1beta (IL-1beta) and its receptor at mRNA and protein level. J Cereb Blood Flow Metab 17:1107-1120
52. Scremin OU (1970) The vascular anatomy of the rat's hypothalamus in stereotaxic coordinates. J Comp Neurol 139:31-52
53. Shibata M, Hori T, Kiyohara T, Nakashima T, Osaka T (1983) Impairment of thermoregulatory cooling behavior by single cortical spreading depression in the rat. Physiol Behav 30:599-605
54. Shibata M, Hori T, Kiyohara T, Nakashima T (1984) Activity of hypothalamic thermosensitive neurons during cortical spreading depression in the rat. Brain Res 308:255-262
55. Stoll G, Jander S, Schroeter M (1998) Inflammation and glial response in ischemic brain lesions. Prog Neurobiol 56:149-171
56. Streit WJ (1995) Microglial cells. In: Kettenmann H, Ransom BR (eds) Neuroglia. Oxford University Press, Oxford, pp 85-96
57. Streit WJ, Graeber MB, Kreutzberg GW (1988) Functional plasticity of microglia: a review. Glia 1:301-307
58. Swanson LW (1976) An autoradiographic study of the efferent connections of the preoptic region in the rat. J Comp Neurol 167:227-256
59. Szelenyi Z, Bartho L, Szekely M, Romanovsky AA (1994). Cholecystokinin octapeptide (CCK-8) injected into a cerebral ventricle induces a fever-like thermoregulatory response mediated by type B CCK-receptors in the rat. Brain Res 638:69-77
60. Tamura A, Graham DI, McCulloch J, Teasdale GM (1981) Focal cerebral ischemia in the rat. 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1:53-60
61. Van Dam AM, Bauer J, Tilders FJ, Berkenbosch F (1995) Endotoxin-induced appearance of immunoreactive interleukin-1 beta in ramified microglia in rat brain: a light-and electron-microscopic study. Neuroscience 65:815-826
62. Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD (1985) Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 17:497-504
63. Zhang Z, Chopp M, Powers C (1997) Temporal profile of microglial response following transient (2 h) middle cerebral artery occlusion. Brain Res 744:189-198
64. Zhang Z, Chopp M, Goussev A, Powers C (1998) Cerebral vessels express interleukin 1beta after focal cerebral ischemia. Brain Res 784:210-217
65. Zhao Q, Memezawa H, Smith ML, Siesjo BK (1994) Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament. Brain Res 649:253-259