gp130-dependent signalling pathway is not enhanced in gp130 transgenic heart after LIF stimulation

Cytokine

Volumn 12, Issue 10, 2000, Pages 1512-1518

  Tone, Eiroh ^a   Kunisada, Keita ^a   Kumanogoh, Atsushi ^b   Negoro, Shinji ^a   Funamoto, Masanobu ^a   Osugi, Tomoaki ^a   Kishimoto, Tadamitsu ^a   Yamauchi Takihara, Keiko ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

JAK; Signal transduction; SSI family; STAT; Transgenic mouse

Indexed keywords

GLYCOPROTEIN GP 130; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYOSIN HEAVY CHAIN; PROTEIN C FOS; PROTEIN INHIBITOR; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE CONSTRUCT; GENE CONTROL; GENE INDUCTION; GENE OVEREXPRESSION; HEART STIMULATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0033785513     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0751     Document Type: Article

References (31)

1. Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development
2. Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor
3. Molecular cloning and expression of an IL-6 signal transducer, gp130
4. Cytokine receptors and signal transduction
5. IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase
6. LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor
7. Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130
8. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6β receptor components
9. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
10. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
11. Signaling mechanisms through gp130: A model of the cytokine system
12. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes
13. Activation of phosphatidylinositol 3-kinase through gp130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes
14. Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes
15. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
16. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
17. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)
18. A cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
19. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
20. A family of cytokine-inducible inhibitors of signaling
21. A new protein containing an SH2 domain that inhibits JAK kinases
22. Structure and function of a new STAT-induced STAT inhibitor
23. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
24. GATA-5 is involved in leukemia inhibitory factor-responsive transcription of the β-myosin heavy chain gene in cardiac myocytes
25. Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction
26. 2-adrenergic receptor
27. 2-adrenoceptor
28. Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice
29. Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130
30. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
31. 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes