-
2
-
-
0035283201
-
Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
-
Mizuno S, Chijiwa T, Okamura T, Akashi K, Fukumaki Y, Niho Y et al. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 2001; 97: 1172-1179.
-
(2001)
Blood
, vol.97
, pp. 1172-1179
-
-
Mizuno, S.1
Chijiwa, T.2
Okamura, T.3
Akashi, K.4
Fukumaki, Y.5
Niho, Y.6
-
3
-
-
0037068312
-
CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
-
Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 2002; 21: 5427-5440.
-
(2002)
Oncogene
, vol.21
, pp. 5427-5440
-
-
Esteller, M.1
-
4
-
-
0035799382
-
Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
-
Santini V, Kantarjian HM, Issa JP. Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann Intern Med 2001; 134: 573-586.
-
(2001)
Ann. Intern. Med.
, vol.134
, pp. 573-586
-
-
Santini, V.1
Kantarjian, H.M.2
Issa, J.P.3
-
5
-
-
0036941943
-
Hypermethylation of gene promoters in hematological neoplasia
-
Chim CS, Liang R, Kwong YL. Hypermethylation of gene promoters in hematological neoplasia. Hematol Onco 2002; 20: 167-176.
-
(2002)
Hematol. Onco.
, vol.20
, pp. 167-176
-
-
Chim, C.S.1
Liang, R.2
Kwong, Y.L.3
-
6
-
-
8244232501
-
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas
-
Malumbres M, Perez de Castro I, Santos J, Melendez B, Mangues R, Serrano M et al. Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas. Oncogene 1997; 14: 1361-1370.
-
(1997)
Oncogene
, vol.14
, pp. 1361-1370
-
-
Malumbres, M.1
Perez de Castro, I.2
Santos, J.3
Melendez, B.4
Mangues, R.5
Serrano, M.6
-
7
-
-
0034600841
-
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis
-
Latres E, Malumbres M, Sotillo R, Martin J, Ortega S, Martin-Caballero J et al. Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis. EMBO J 2000; 19: 3496-3506.
-
(2000)
EMBO J.
, vol.19
, pp. 3496-3506
-
-
Latres, E.1
Malumbres, M.2
Sotillo, R.3
Martin, J.4
Ortega, S.5
Martin-Caballero, J.6
-
8
-
-
0031595991
-
Expression of p15INK4B in normal hematopoiesis
-
Teofili L, Rutella S, Chiusolo P, La Barbera EO, Rumi C, Ranelletti FO et al. Expression of p15INK4B in normal hematopoiesis. Exp Hematol 1998; 26: 1133-1139.
-
(1998)
Exp. Hematol.
, vol.26
, pp. 1133-1139
-
-
Teofili, L.1
Rutella, S.2
Chiusolo, P.3
La Barbera, E.O.4
Rumi, C.5
Ranelletti, F.O.6
-
9
-
-
0034104765
-
Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation
-
Teofili L, Morosetti R, Martini M, Urbano R, Putzulu R, Rutella S et al. Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation. Exp Hematol 2000; 28: 519-526.
-
(2000)
Exp. Hematol.
, vol.28
, pp. 519-526
-
-
Teofili, L.1
Morosetti, R.2
Martini, M.3
Urbano, R.4
Putzulu, R.5
Rutella, S.6
-
10
-
-
0034773580
-
Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development
-
Sakashita K, Koike K, Kinoshita T, Shiohara M, Kamijo T, Taniguchi S et al. Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development. J Clin Invest 2001; 108: 1195-1204.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1195-1204
-
-
Sakashita, K.1
Koike, K.2
Kinoshita, T.3
Shiohara, M.4
Kamijo, T.5
Taniguchi, S.6
-
11
-
-
0035880261
-
Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors
-
Teofili L, Martini M, Di Mario A, Rutella S, Urbano R, Luongo M et al. Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors. Blood 2001; 98: 495-497.
-
(2001)
Blood
, vol.98
, pp. 495-497
-
-
Teofili, L.1
Martini, M.2
Di Mario, A.3
Rutella, S.4
Urbano, R.5
Luongo, M.6
-
12
-
-
0034654269
-
Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
-
Wong IH, Ng MH, Huang DP, Lee JC. Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications. Blood 2000; 95: 1942-1949.
-
(2000)
Blood
, vol.95
, pp. 1942-1949
-
-
Wong, I.H.1
Ng, M.H.2
Huang, D.P.3
Lee, J.C.4
-
13
-
-
0035300727
-
Methylation of p15 and p16 genes in acute promyelocytic leukemia: Potential diagnostic and prognostic significance
-
Chim CS, Liang R, Tam CY, Kwong YL. Methylation of p15 and p16 genes in acute promyelocytic leukemia: potential diagnostic and prognostic significance. J Clin Oncol 2001; 19: 2033-2040.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 2033-2040
-
-
Chim, C.S.1
Liang, R.2
Tam, C.Y.3
Kwong, Y.L.4
-
14
-
-
0031025368
-
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies
-
Herman JG, Civin CI, Issa JP, Collector MI, Sharkis SJ, Baylin SB. Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Res 1997; 57: 837-841.
-
(1997)
Cancer Res.
, vol.57
, pp. 837-841
-
-
Herman, J.G.1
Civin, C.I.2
Issa, J.P.3
Collector, M.I.4
Sharkis, S.J.5
Baylin, S.B.6
-
17
-
-
0042096382
-
Important features of myelodysplastic syndrome
-
Hofmann WK, Koeffler HP. Important features of myelodysplastic syndrome. Int J Hematol 2002; 76 (Suppl 2): 222-227.
-
(2002)
Int. J. Hematol.
, vol.76
, Issue.SUPPL. 2
, pp. 222-227
-
-
Hofmann, W.K.1
Koeffler, H.P.2
-
19
-
-
0035134705
-
INK4B gene in myelodysplastic syndrome: It can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation
-
INK4B gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation. Br J Haematol 2001; 112: 148-154.
-
(2001)
Br. J. Haematol.
, vol.112
, pp. 148-154
-
-
Tien, H.F.1
Tang, J.L.2
Tsay, W.3
Liu, M.C.4
Lee, F.Y.5
Wang, C.H.6
-
20
-
-
0034740657
-
p15INK4B gene methylation and expression in normal, myelodysplastic, and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients
-
Preisler HD, Li B, Chen H, Fisher L, Nayini J, Raza A et al. p15INK4B gene methylation and expression in normal, myelodysplastic, and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients. Leukemia 2001; 15:: 1589-1595.
-
(2001)
Leukemia
, vol.15
, pp. 1589-1595
-
-
Preisler, H.D.1
Li, B.2
Chen, H.3
Fisher, L.4
Nayini, J.5
Raza, A.6
-
21
-
-
0037108309
-
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′deoxycytidine (decitabine) treatment
-
Daskalakis M, Ngyuyen TT, Nguyen C, Guldberg P, Köhler G, Wijermans P et al. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′deoxycytidine (decitabine) treatment. Blood 2002; 100: 2957-2963.
-
(2002)
Blood
, vol.100
, pp. 2957-2963
-
-
Daskalakis, M.1
Ngyuyen, T.T.2
Nguyen, C.3
Guldberg, P.4
Köhler, G.5
Wijermans, P.6
-
22
-
-
0036316318
-
Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes
-
Chen H, Wu S. Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes. Chin Med J 2002; 115: 987-990.
-
(2002)
Chin. Med. J.
, vol.115
, pp. 987-990
-
-
Chen, H.1
Wu, S.2
-
23
-
-
0037356973
-
Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: Clincopathological and karyotypic associations
-
Au WY, Fung A, Man C, Ma SK, Wan TS, Liang R et al. Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clincopathological and karyotypic associations. Br J Haematol 2003; 120: 1062-1065.
-
(2003)
Br. J. Haematol.
, vol.120
, pp. 1062-1065
-
-
Au, W.Y.1
Fung, A.2
Man, C.3
Ma, S.K.4
Wan, T.S.5
Liang, R.6
-
24
-
-
0035802289
-
Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells
-
Nguyen C, Liang G, Ngyuen TT, Tsao-Wie D, Groshen S, Lübbert M et al. Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells. J Natl Canc Inst 2001; 93: 1465-1472.
-
(2001)
J. Natl. Canc. Inst.
, vol.93
, pp. 1465-1472
-
-
Nguyen, C.1
Liang, G.2
Ngyuen, T.T.3
Tsao-Wie, D.4
Groshen, S.5
Lübbert, M.6
-
25
-
-
0033153303
-
The human DNA methyltransferases (DNMTs)1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA et al. The human DNA methyltransferases (DNMTs)1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999; 27: 2291-2298.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgyi, E.2
Liang, G.3
Talmadge, C.4
Sumegi, J.5
Gonzales, F.A.6
-
27
-
-
0033563083
-
CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
-
Eads CA, Danenberg KD, Kawakami K, Saltz LB, Danenberg PV, Laird P. CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res 1999; 59: 2302-2306.
-
(1999)
Cancer Res.
, vol.59
, pp. 2302-2306
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Danenberg, P.V.5
Laird, P.6
-
28
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee I, Bachmann KE, Park BH, Jair KW, Yen RW, Schuebel KE et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002; 416: 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachmann, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
-
29
-
-
0037179870
-
Hypomethylation and hypermethylation of DNA in Wilm's tumors
-
Ehrlich M, Jiang G, Fiala F, Dome JS, Yu MC, Long TI et al. Hypomethylation and hypermethylation of DNA in Wilm's tumors. Oncogene 2002; 21: 6694-6702.
-
(2002)
Oncogene
, vol.21
, pp. 6694-6702
-
-
Ehrlich, M.1
Jiang, G.2
Fiala, F.3
Dome, J.S.4
Yu, M.C.5
Long, T.I.6
-
30
-
-
0035890665
-
Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: Correlation of accessibility, methylation, MeCP2 binding and acetylation
-
Nguyen CT, Gonzales FA, Jones PA. Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation. Nucleic Acids Res 2001; 29: 4598-4606.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 4598-4606
-
-
Nguyen, C.T.1
Gonzales, F.A.2
Jones, P.A.3
-
31
-
-
17444452612
-
Low-dose 5-Aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome; a multicenter phase II study in elderly patients
-
Wijermans PW, Lübbert M, Verhoef G, Bosly A, Ravoet C, Andre M et al. Low-dose 5-Aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome; a multicenter phase II study in elderly patients. J Clin Oncol 2000; 18: 956-962.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 956-962
-
-
Wijermans, P.W.1
Lübbert, M.2
Verhoef, G.3
Bosly, A.4
Ravoet, C.5
Andre, M.6
-
32
-
-
0037093195
-
Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: A study of the cancer and leukemia group B
-
Silverman LR, Demakos EP, Peterson BL, Kornblith AB, Holland JC, Odchimar-Reissig R et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. J Clin Oncol 2002; 20: 2429-2440.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2429-2440
-
-
Silverman, L.R.1
Demakos, E.P.2
Peterson, B.L.3
Kornblith, A.B.4
Holland, J.C.5
Odchimar-Reissig, R.6
-
33
-
-
0031964055
-
Inhibition of DNA methylation by 5-Aza-2′-deoxycytidine suppresses the growth of human tumor cell lines
-
Bender CM, Pao MM, Jones PA. Inhibition of DNA methylation by 5-Aza-2′-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res 1998; 58: 95-101.
-
(1998)
Cancer Res.
, vol.58
, pp. 95-101
-
-
Bender, C.M.1
Pao, M.M.2
Jones, P.A.3
|