In Vivo Interrogation of the Molecular Display of Atherosclerotic Lesion Surfaces

American Journal of Pathology

Volumn 163, Issue 5, 2003, Pages 1859-1871

  Liu, Cheng ^a,c   Bhattacharjee, Gourab ^a   Boisvert, William ^a   Dilley, Ralph ^b   Edgington, Thomas ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS CLINIC   (United States)

^c Mail Code C204 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 78; PEPTIDE; PEPTIDE LIBRARY; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; IN VIVO STUDY; KNOCKOUT MOUSE; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; THROMBOSIS;

EID: 0142213218     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63545-6     Document Type: Article

References (57)

1. Libby P: Changing concepts of atherogenesis. J Intern Med 2000, 247:349-358
2. Faggiotto A, Ross R: Studies of hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque. Arteriosclerosis 1984, 4:341-356
3. Rosenfeld ME, Tsukada T, Gown AM, Ross R: Fatty streak initiation in Watanabe heritable hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis 1987, 7:9-23
4. Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809
5. Ross R: Atherosclerosis: current understanding of mechanisms and future strategies in therapy. Transplant Proc 1993, 25:2041-2043
6. Fuster V: Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology [published erratum appears in Circulation 1995 Jan 1;91(1):256]. Circulation 1994, 90:2126-2146
7. Fuster V: Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology [published erratum appears in Circulation 1995 Jan 1;91(1):256]. Circulation 1994, 90:2126-2146
8. Dong ZM, Chapman SM, Brown AA, Frenette PS, Hynes RO, Wagner DD: The combined role of P- and E-selectins in atherosclerosis. J Clin Invest 1998, 102:145-152
9. Cybulsky MI, Gimbrone JR MA: Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 1991, 251:788-791
10. Boisvert WA, Black AS, Curtiss LK: ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages. Arterioscler Thromb Vasc Biol 1999, 19:525-530
11. Curtiss LK, Boisvert WA: Apolipoprotein E and atherosclerosis. Curr Opin Lipidol 2000, 11:243-251
12. Pasqualini R, Ruoslahti E: Organ targeting in vivo using phage display peptide libraries. Nature 1996, 380:364-366
13. Vachon V, Pouliot JF, Laprade R, Beliveau R: Fractionation of renal brush border membrane proteins with Triton X-114 phase partitioning. Biochem Cell Biol 1991, 69:206-211
14. Perkins DN, Pappin DJ, Creasy DM, Cottrell JS: Probability-based protein identification by searching sequence databases using mass spectrometry data. Efectrophoresis 1999, 20:3551-3567
15. Fernandez-Catalan C, Bode W, Huber R, Turk D, Calvete JJ, Lichte A, Tschesche H, Maskos K: Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. EMBO J 1998, 17:5238-5248
16. Chesler L, Golde DW, Bersch N, Johnson MD: Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1. Blood 1995, 86:4506-4515
17. Corcoran ML, Stetler-Stevenson WG: Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J Biol Chem 1995, 270:13453-13459
18. Nishimoto M, Takai S, Kim S, Jin D, Yuda A, Sakaguchi M, Yamada M, Sawada Y, Kondo K, Asada K, Iwao H, Sasaki S, Miyazaki M: Significance of chymase-dependent angiotensin II-forming pathway in the development of vascular proliferation. Circulation 2001, 104:1274-1279
19. Katugampola SD, Davenport AP: Radioligand binding reveals chymase as the predominant enzyme for mediating tissue conversion of angiotensin I in the normal human heart. Clin Sci (Lond) 2002, 102:15-21
20. Miyazaki M, Takai S: Local angiotensin II-generating system in vascular tissues: the roles of chymase. Hypertens Res 2001, 24:189-193
21. Kolonin M, Pasqualini R, Arap W: Molecular addresses in blood vessels as targets for therapy. Curr Opin Chem Biol 2001, 5:308-313
22. Tressler RJ, Belloni PN, Nicolson GL: Correlation of inhibition of adhesion of large cell lymphoma and hepatic sinusoidal endothelial cells by RGD-containing peptide polymers with metastatic potential: role of integrin-dependent and -independent adhesion mechanisms. Cancer Commun 1989, 1:55-63
23. Gething MJ: Role and regulation of the ER chaperone BiP. Semin Cell Dev Biol 1999, 10:465-472
24. Triantafilou M, Fradelizi D, Triantafilou K: Major histocompatibility class one molecule associates with glucose regulated protein (GRP) 78 on the cell surface. Hum Immunol 2001, 62:764-770
25. Misra UK, Gonzalez-Gronow M, Gawdi G, Hart JP, Johnson CE, Pizzo SV: The role of Grp 78 in alpha 2-macroglobulin-induced signal transduction. Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction. J Biol Chem 2002, 277:42082-42087
26. Bhattacharjee G, Misra UK, Gawdi G, Cianciolo G, Pizzo SV: Inducible expression of the alpha2-macroglobulin signaling receptor in response to antigenic stimulation: a study of second messenger generation. J Cell Biochem 2001, 82:260-270
27. Misra UK, Gonzalez-Gronow M, Gawdi G, Pizzo SV: Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts. J Biol Chem 1997, 272:497-502
28. Asplin IR, Misra UK, Gawdi G, Gonzalez-Gronow M, Pizzo SV: Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells. Arch Biochem Biophys 2000, 383:135-141
29. Jorgensen MM, Jensen ON, Holst HU, Hansen JJ, Corydon TJ, Bross P, Bolund L, Gregersen N: Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum. J Biol Chem 2000, 275:33861-33868
30. Triantafilou K, Fradelizi D, Wilson K, Triantafilou M: GRP78, a coreceptor for coxsackievirus A9, interacts with major histocompatibility complex class I molecules which mediate virus internalization. J Virol 2002, 76:633-643
31. Cybulsky MI, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, Davis V, Gutierrez-Ramos JC, Connelly PW, Milstone DS: A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J Clin Invest 2001, 107:1255-1262
32. Kinlay S, Libby P, Ganz P: Endothelial function and coronary artery disease. Curr Opin Lipidol 2001, 12:383-389
33. Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE, Yoffe B: Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 2002, 36:592-601
34. van der Vlies D, Pap EH, Post JA, Celis JE, Wirtz KW: Endoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxide. Biochem J 2002, 366:825-830
35. Miyata T, Kokame K, Agarwala KL, Kato H: Analysis of gene expression in homocysteine-injured vascular endothelial cells: demonstration of GRP78/BiP expression, cloning and characterization of a novel reducing agent-tunicamycin regulated gene. Semin Thromb Hemost 1998, 24:285-291
36. Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, Austin RC: Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 2001, 107:1263-1273
37. Linnik KM, Herscovitz H: Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state. J Biol Chem 1998, 273:21368-21373
38. Watson LM, Chan AK, Berry LR, Li J, Sood SK, Dickhout JG, Xu L, Werstuck GH, Bajzar L, Klamut HJ, Austin RC: Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity. J Biol Chem 2003, 278:17438-17447
39. Bello L, Lucini V, Carrabba G, Giussani C, Machluf M, Pluderi M, Nikas D, Zhang J, Tomei G, Villani RM, Carroll RS, Bikfalvi A, Black PM: Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2. Cancer Res 2001, 61:8730-8736
40. Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP: Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 1997, 74:111-122
41. George SJ: Therapeutic potential of matrix metalloproteinase inhibitors in atherosclerosis. Expert Opin Investig Drugs 2000, 9:993-1007
42. van der Wal AC, Becker AE, van der Loos CM, Das PK: Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994, 89:36-44
43. Lendon CL, Davies MJ, Born GV, Richardson PD: Atheroscterotic plaque caps are locally weakened when macrophages density is increased. Atherosclerosis 1991, 87:87-90
44. Krieger M, Acton S, Ashkenas J, Pearson A, Penman M, Resnick D: Molecular flypaper, host defense, and atherosclerosis. Structure, binding properties, and functions of macrophage scavenger receptors. J Biol Chem 1993, 268:4569-4572
45. Endemann G, Stanton LW, Madden KS, Bryant CM, White RT, Protter AA: CD36 is a receptor for oxidized low density lipoprotein. J Biol Chem 1993, 268:11811-11816
46. Ottnad E, Parthasarathy S, Sambrano GR, Ramprasad MP, Quehenberger O, Kondratenko N, Green S, Steinberg D: A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells. Proc Natl Acad Sci USA 1995, 92:1391-1395
47. Ramprasad MP, Fischer W, Witztum JL, Sambrano GR, Quehenberger O, Steinberg D: The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68. Proc Natl Acad Sci USA 1995, 92:9580-9584
48. Acton S, Rigotti,A, Landschulz KT, Xu S, Hobbs HH, Krieger M: Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 1996, 271:518-520
49. Gu X, Trigatti B, Xu S, Acton S, Babitt J, Krieger M: The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain. J Biol Chem 1998, 273:26338-26348
50. Watson AD, Leitinger N, Navab M, Faull KF, Horkko S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM, Berliner JA: Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J Biol Chem 1997, 272:13597-13607
51. Witztum JL, Berliner JA: Oxidized phospholipids and isoprostanes in atherosclerosis. Curr Opin Lipidol 1998, 9:441-448
52. Berliner J, Leitinger N, Watson A, Huber J, Fogelman A, Navab M: Oxidized lipids in atherogenesis: formation, destruction and action. Thromb Haemost 1997, 78:195-199
53. Gimbrone Jr MA, Topper JN, Nagel T, Anderson KR, Garcia-Cardena G: Endothelial dysfunction, hemodynamic forces, and atherogenesis. Ann NY Acad Sci 2000, 902:230-240
54. Gimbrone Jr MA, Nagel T, Topper JN: Biomechanical activation: an emerging paradigm in endothelial adhesion biology. J Clin Invest 1997, 99:1809-1813
55. Carlos TM, Harlan JM: Leukocyte-endothelial adhesion molecules. Blood 1994, 84:2068-2101
56. Frenette PS, Wagner DD: Adhesion molecules - Part 1. N Engl J Med 1996, 334:1526-1529
57. Frenette PS, Wagner DD: Adhesion molecules - Part II: blood vessels and blood cells. N Engl J Med 1996, 335:43-45