Identification of in vitro growth conditions for c-Kit-negative hematopoietic stem cells

Blood

Volumn 102, Issue 9, 2003, Pages 3120-3128

  Klarmann, Kim ^a   Ortiz, Mariaestela ^c   Davies, Meghan ^c   Keller, Jonathan R ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; LEUKOSIALIN; STEM CELL ANTIGEN 1; STEM CELL FACTOR; THY 1 ANTIGEN; THY 1.2 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; COLONY FORMING UNIT; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STROMA CELL;

EID: 0142183474     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-04-1249     Document Type: Article

References (47)

1. Chung LL, Johnson GR. Murine hematopoietic stem and progenitor cells: I. enrichment and biologic characterization. Blood. 1995;85:1472-1479.
2. Spangrude GJ, Scollay R. A simplified method for enrichment of mouse hematopoietic stem cells. Exp Hematol. 1990;18:920-926.
3. Yamamoto Y, Yasumizu R, Amou Y, et al. Characterization of peripheral blood stem cells in mice. Blood. 1996;88:445-454.
4. Ploemacher RE, Brons NHC. Isolation of hemopoietic stem cell subsets from murine bone marrow: 1. radioprotective ability of purified cell suspensions differing in the proportion of day-7 and day-12 CFU-s. Exp Hem. 1988;16:21-26.
5. Russell ES. Hereditary anemias of the mouse: a review for geneticists. Adv Genet. 1979;20:357-459.
6. Silvers WK. In the Coat Colors of Mice: A Model for Mammalian Gene Actions and Interaction. New York, NY: Springer Verlag; 1979:243-267.
7. Ogawa M, Matsuzaki Y, Nishikawa S, et al. Expresion and function of c-Kit in hemopoietic progenitor cells. J Exp Med. 1991;174:63-71.
8. Ogawa M, Nishikawa S, Yoshinaga K, et al. Expression and function of c-Kit in fetal hematopoietic progenitor cells: transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo. Development. 1993;117:1089-1098.
9. Okada S, Nakauchi H, Nagayoshi K, et al. Enrichment and characteriazation of murine hemmatopoietic stem cells that express c-kit molecule. Blood. 1991;78:1706-1712.
10. Ortiz M, Wine JW, Lohrey N, Ruscetti FW, Spence SE, Keller JR. Functional characterization of a novel hematopoietic stem cell and its place in the c-Kit maturation pathway in bone marrow cell development. Immunity. 1999;10: 173-182.
11. Yagi M, Ritchie KA, Sitnicka E, Storey C, Roth GJ, Bartelmez S. Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin. Proc Nat Acad Sci U S A. 1999;96:8126-8131.
12. Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science. 1996;273:242-245.
13. -: does it really matter? Blood. 1999;94:2545-2547.
14. Moore TS, Huang S, Terstappen LWMM, Bennet M, Kuman V. Expression of CD43 on murine and human pluripotent hematopoietic stem cells. Immunol. 1994;153:4978-4987.
15. Spangrude GJ, Brooks DM. Phenotypic analysis of mouse hematopoietic stem cells shows a Thy 1-negative subset. Blood. 1992;80:1957-1964.
16. Szilvassy SJ, Cory S. Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow. Blood. 1993;81:2310-2320.
17. Ito CY, Li CY, Bernstein A, Dick JE, Stanford WL. Hematopoietic stem cell and progenitor defects in Sca.1/Ly-6A-null mice. Blood. 2003;101:517-523.
18. Spangrude GJ, Johnson GR. Resting and activated subsets of mouse multipotent hematopoietic stem cells. Proc Natl Acad Sci U S A. 1990; 87:7433-7437.
19. Keller JK, Mcniece IK, Sill KT, et al. Transforming growth factor β directly regulates primitive murine hematopoietic cell proliferation. Blood. 1990;75: 596-602.
20. 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells. Blood. 1996;88:82-88.
21. Varnum-Finney B, Xu L, Brashem-Stein C, et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat Med. 2000;6:1278-1281.
22. Jones P, May G, Healy L, et al. Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells. Blood. 1998; 92:1505-1511.
23. Varnum-Finney B, Purton LE, Yu M, et al. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood. 1998;91:4084-4091.
24. Varnum-Finney B, Ohishi K, Bernstein ID. Hematopoietic precursors cultured with notch ligand, Delta 1, engraft the thymus of non-irradiated Rag1-/- mice [abstract]. Blood. 2002;100:2393.
25. Varnum-Finney B, Brashem-Stein C, Bernstein ID. Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability. Blood. 2003;101:1784-1789.
26. Kennedy M, Firpo M, Choi K, et al. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature. 1997;386:488-493.
27. Nakano T. In vitro development of hematopoietic system from mouse embryonic stem cells: a new approach for embryonic hematopoiesis. Int J Hematol. 1996;65:1-8.
28. Zipori D, Toledo J, von der Mark K. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular matrix composition and interactions with normal and leukemic cells. Blood. 1985;66:447-455.
29. Collins LS, Dorshkind K. A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis. J Immunol. 1987;138:1082-1087.
30. Sutherland HJ, Eaves CJ, Lansdorp PM, Thacker JD, Hogge DE. Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood. 1991;78:666-672.
31. Cohler A, Langer JC, Henckaerts E, Snoeck H-W. Characterization of bone marrow Lin-Sca1 ++ kit-cells [abstract]. Blood. 2002;100:4116.
32. Jones RJ, Collector MI, Barber JP, et al. Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity. Blood. 1996;88:487-491.
33. Randall TD, Weissman IL. Characterization of a population of cells in the bone marrow that phenotypically mimics hematopoietic stem cells: resting stem cells or mystery population? Stem Cells. 1998;16:38-48.
34. Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183:1797-1806.
35. Goodell MA, Rosenzweig M, Kim H, et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med. 1997;3:1337-1345.
36. Jacobsen SE, Borge OJ, Ramsfjell V, et al. Thrombopoietin, a direct stimulator of viability and multilineage growth of primitive bone marrow progenitor cells. Stem Cells. 1996;14(suppl 1):173-180.
37. Broxmeyer HE, Cooper S, Kohli L, et al. Transgenic expression of stromal cell-derived factor-1/ CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo. J Immunol. 2003; 170:421-429.
38. Kijima T, Maulik G, Ma PC, et al. Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells. Cancer Res. 2002; 62:6304-6311.
39. Glimm H, Tang P, Clark-Lewis I, von Kalle C, Eaves C. Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor-1 enhances their ability to engraft NOD/SCID mice. Blood. 2002;99:3454-3457.
40. Dasch JR, Pace DR, Waegell W, Inenaga D, Ellingsworth L. Monoclonal antibodies recognizing transforming growth factor-beta: bioactivity neutralization and transforming growth factor beta 2 affinity purification. J Immunol. 1989;142:1536-1541.
41. Ploemacher RE, van Soest PL, Boudewijn A. Autocrine transforming growth factor beta 1 blocks colony formation and progenitor cell generation by hemopoietic stem cells stimulated with steel factor. Stem Cells. 1993;11:336-347.
42. Fortunel N, Hatzfeld J, Kisselev S, et al. Release from quiescence of primitive human hematopoietic stem/progenitor cells by blocking their cell-surface TGF-beta type II receptor in a short-term in vitro assay. Stem Cells. 2000;18:102-111.
43. Howell J, Yoder M, Srour E. Functional properties of muscle-derived CD45-Sca-1+c-Kit-cells fractionated on the basis of CD34 and Thy-1.2 expression. Exp Hematol. 2002;30:364.
44. Li CL, Johnson GR. Murine hematopoietic stem and progenitor cells: I. enrichment and biologic characterization. Blood. 1995;85:1472-1479.
45. Keller JR. Stem cell quiescence and activation. Mod Asp Immunobiol. 2001;1:217-220.