-
1
-
-
0035068731
-
Physiological modeling reveals novel pharmacokinetic behavior for inhaled octamethylcyclotetrasiloxane in rats
-
Andersen M.E., Sarangapani R., Reitz R.H., Gallavan R.H., Debrev I.D., Plotzke K.P. Physiological modeling reveals novel pharmacokinetic behavior for inhaled octamethylcyclotetrasiloxane in rats. Toxicol. Sci. 60:2001;214-231.
-
(2001)
Toxicol. Sci.
, vol.60
, pp. 214-231
-
-
Andersen, M.E.1
Sarangapani, R.2
Reitz, R.H.3
Gallavan, R.H.4
Debrev, I.D.5
Plotzke, K.P.6
-
3
-
-
0029877913
-
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
-
Bunone G., Briand P.A., Miksicek R.J., Picard D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J. 15:1996;2174-2183.
-
(1996)
EMBO J.
, vol.15
, pp. 2174-2183
-
-
Bunone, G.1
Briand, P.A.2
Miksicek, R.J.3
Picard, D.4
-
4
-
-
0036218589
-
Inhalation toxicology of octamethylcyclotetrasiloxane (D4) following a 3-month nose-only exposure in Fischer 344 rats
-
Burns-Naas L.A., Meeks R.G., Kolesar G.B., Mast R.W., Elwell M.R., Hardisty J.F., Thevenaz P. Inhalation toxicology of octamethylcyclotetrasiloxane (D4) following a 3-month nose-only exposure in Fischer 344 rats. Int. J. Toxicol. 21:2002;39-53.
-
(2002)
Int. J. Toxicol.
, vol.21
, pp. 39-53
-
-
Burns-Naas, L.A.1
Meeks, R.G.2
Kolesar, G.B.3
Mast, R.W.4
Elwell, M.R.5
Hardisty, J.F.6
Thevenaz, P.7
-
5
-
-
0030954444
-
Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium
-
Cooke P.S., Buchanan D.L., Young P., Setiawan T., Brody J., Korach K.S., Taylor J., Lubahn D.B., Cunha G.R. Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium. Proc. Natl. Acad. Sci. USA. 94:1997;6535-6540.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6535-6540
-
-
Cooke, P.S.1
Buchanan, D.L.2
Young, P.3
Setiawan, T.4
Brody, J.5
Korach, K.S.6
Taylor, J.7
Lubahn, D.B.8
Cunha, G.R.9
-
6
-
-
0033305438
-
Estrogen receptor null mice: What have we learned and where will they lead us
-
Couse J.F., Korach K.S. Estrogen receptor null mice what have we learned and where will they lead us . Endocr. Rev. 20:1999;358-417.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 358-417
-
-
Couse, J.F.1
Korach, K.S.2
-
7
-
-
33846832319
-
Effects of octamethylcyclotetrasiloxane (D4) and phenobarbital (PB) on LH surge and ovulation in Sprague-Dawley (SD) rats
-
Dalu A., Gallavan R.H., Meeker L.S., Quinn A.L., Jean P.A., Crissman J.W., Meeks B.G., Plotzke K.P. Effects of octamethylcyclotetrasiloxane (D4) and phenobarbital (PB) on LH surge and ovulation in Sprague-Dawley (SD) rats. Toxicologist. 66:(1S):2002;343-344.
-
(2002)
Toxicologist
, vol.66
, Issue.1S
, pp. 343-344
-
-
Dalu, A.1
Gallavan, R.H.2
Meeker, L.S.3
Quinn, A.L.4
Jean, P.A.5
Crissman, J.W.6
Meeks, B.G.7
Plotzke, K.P.8
-
8
-
-
0031606938
-
Activation of c-Neu tyrosine kinase by o,p′-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells
-
Enan E., Matsumura F. Activation of c-Neu tyrosine kinase by o,p′-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells. J. Biochem. Mol. Toxicol. 12:1998;83-92.
-
(1998)
J. Biochem. Mol. Toxicol.
, vol.12
, pp. 83-92
-
-
Enan, E.1
Matsumura, F.2
-
9
-
-
0030733906
-
Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern
-
Enmark E., Pelto-Huikko M., Grandien K.A.J., Lagercrantz S., Lagercrantz J., Fried G., Nordenskjold M., Gustafsson J.-A. Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern. J. Clin. Endocrinol. Metab. 82:1997;4258-4265.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4258-4265
-
-
Enmark, E.1
Pelto-Huikko, M.2
Grandien, K.A.J.3
Lagercrantz, S.4
Lagercrantz, J.5
Fried, G.6
Nordenskjold, M.7
Gustafsson, J.-A.8
-
10
-
-
0030199499
-
Effect of growth factors on estrogen receptor mediated gene expression
-
Hafner F., Holler E., vonAngerer E. Effect of growth factors on estrogen receptor mediated gene expression. J. Steroid Biochem. Mol. Biol. 58:1996;385-393.
-
(1996)
J. Steroid Biochem. Mol. Biol.
, vol.58
, pp. 385-393
-
-
Hafner, F.1
Holler, E.2
VonAngerer, E.3
-
11
-
-
0034663421
-
ICI 182,780 (Faslodex): Development of a novel, "pure" antiestrogen
-
Howell A., Osborne C.K., Morris C., Wakeling A.E. ICI 182,780 (Faslodex) development of a novel, "pure" antiestrogen . Cancer. 89:2000;817-825.
-
(2000)
Cancer
, vol.89
, pp. 817-825
-
-
Howell, A.1
Osborne, C.K.2
Morris, C.3
Wakeling, A.E.4
-
12
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S., Endoh H., Masuhiro Y., Kitamoto T., Uchiyama S., Sasaki H., Musushige S., Gotoh Y., Nishida E., Kawashima H., Metzger D., Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science. 270:1995;1491-1494.
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Musushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
Metzger, D.11
Chambon, P.12
-
13
-
-
0033643115
-
Estrogen receptor knock-out mice: Molecular and endocrine phenotypes
-
Korach K.S. Estrogen receptor knock-out mice molecular and endocrine phenotypes . J. Soc. Gynecol. Invest. 7:(S):2000;16-17.
-
(2000)
J. Soc. Gynecol. Invest.
, vol.7
, Issue.S
, pp. 16-17
-
-
Korach, K.S.1
-
14
-
-
0031039888
-
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
-
Kuiper G.G., Carlsson B., Grandien K., Enmark E., Haggblad J., Nilsson S., Gustafsson J.A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 138:1997;863-870.
-
(1997)
Endocrinology
, vol.138
, pp. 863-870
-
-
Kuiper, G.G.1
Carlsson, B.2
Grandien, K.3
Enmark, E.4
Haggblad, J.5
Nilsson, S.6
Gustafsson, J.A.7
-
16
-
-
0142202998
-
The effect of octamethylcyclotetrasiloxane (D4) on the humoral immune responses in B6C3F1 mice
-
LeVier D.G., Musgrove D.L., Munson A.E. The effect of octamethylcyclotetrasiloxane (D4) on the humoral immune responses in B6C3F1 mice. The Toxicologist. 15:1995;223.
-
(1995)
The Toxicologist
, vol.15
, pp. 223
-
-
LeVier, D.G.1
Musgrove, D.L.2
Munson, A.E.3
-
17
-
-
2442464650
-
Uterine peroxidase as a marker for estrogen action
-
Lyttle C.R., DeSombre E.R. Uterine peroxidase as a marker for estrogen action. Proc. Natl. Acad. Sci. USA. 74:1977;3162-3166.
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 3162-3166
-
-
Lyttle, C.R.1
DeSombre, E.R.2
-
18
-
-
0142171940
-
Inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D4) in female rats
-
Mast R.W., Holson J.F., Stump D.G., Nemec M.D., Reynolds V.L. Inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D4) in female rats. The Toxicologist. 36:1997;357.
-
(1997)
The Toxicologist
, vol.36
, pp. 357
-
-
Mast, R.W.1
Holson, J.F.2
Stump, D.G.3
Nemec, M.D.4
Reynolds, V.L.5
-
19
-
-
0032764718
-
Induction of hepatic xenobiotic metabolizing enzymes in female Fischer-344 rats following repeated inhalation exposure to decamethylcyclopentasiloxane (D5)
-
McKim J.M. Jr., Choudhuri S., Wilga P.C., Madan A., Burns-Naas L.A., Gallavan R.H., Mast R.W., Naas D.J., Parkinson A., Meeks R.G. Induction of hepatic xenobiotic metabolizing enzymes in female Fischer-344 rats following repeated inhalation exposure to decamethylcyclopentasiloxane (D5). Toxicol. Sci. 50:1999;10-19.
-
(1999)
Toxicol. Sci.
, vol.50
, pp. 10-19
-
-
McKim J.M., Jr.1
Choudhuri, S.2
Wilga, P.C.3
Madan, A.4
Burns-Naas, L.A.5
Gallavan, R.H.6
Mast, R.W.7
Naas, D.J.8
Parkinson, A.9
Meeks, R.G.10
-
20
-
-
0034874728
-
Potential estrogenic and antiestrogenic activity of the cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) in immature rats using the uterotrophic assay
-
McKim J.M. Jr., Wilga P.C., Breslin W.J., Plotzke K.P., Gallavan R.H., Meeks R.G. Potential estrogenic and antiestrogenic activity of the cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) in immature rats using the uterotrophic assay. Toxicol. Sci. 63:2001;37-46.
-
(2001)
Toxicol. Sci.
, vol.63
, pp. 37-46
-
-
McKim J.M., Jr.1
Wilga, P.C.2
Breslin, W.J.3
Plotzke, K.P.4
Gallavan, R.H.5
Meeks, R.G.6
-
21
-
-
0031594803
-
Evaluation of octamethylcyclotetrasiloxane (D4) as an inducer of rat hepatic microsomal cytochrome P450, UDP-glucuronosyltransferase, and epoxide hydrolase: A 28-day inhalation study
-
McKim J.M. Jr., Wilga P.C., Kolesar G.B., Choudhuri S., Madan A., Dochterman L.W., Breen J.G., Parkinson A., Mast R.W., Meeks R.G. Evaluation of octamethylcyclotetrasiloxane (D4) as an inducer of rat hepatic microsomal cytochrome P450, UDP-glucuronosyltransferase, and epoxide hydrolase a 28-day inhalation study . Toxicol. Sci. 41:1998;29-41.
-
(1998)
Toxicol. Sci.
, vol.41
, pp. 29-41
-
-
McKim J.M., Jr.1
Wilga, P.C.2
Kolesar, G.B.3
Choudhuri, S.4
Madan, A.5
Dochterman, L.W.6
Breen, J.G.7
Parkinson, A.8
Mast, R.W.9
Meeks, R.G.10
-
22
-
-
0008742179
-
1-Month repeated dose inhalation toxicity study with octamethylcyclotetrasiloxane in rats
-
Meeks R.G., Thevenaz P., Mast R.W. 1-Month repeated dose inhalation toxicity study with octamethylcyclotetrasiloxane in rats. The Toxicologist. 15:1995;182.
-
(1995)
The Toxicologist
, vol.15
, pp. 182
-
-
Meeks, R.G.1
Thevenaz, P.2
Mast, R.W.3
-
23
-
-
13044267130
-
Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha
-
Orimo A., Inoue S., Minowa O., Tominaga N., Tomioka Y., Sato M., Kuno J., Hiroi H., Shimizu Y., Suzuki M., Noda T., Muramatsu M. Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha. Proc. Natl. Acad. Sci. USA. 96:1999;12027-12032.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12027-12032
-
-
Orimo, A.1
Inoue, S.2
Minowa, O.3
Tominaga, N.4
Tomioka, Y.5
Sato, M.6
Kuno, J.7
Hiroi, H.8
Shimizu, Y.9
Suzuki, M.10
Noda, T.11
Muramatsu, M.12
-
24
-
-
0030801841
-
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites
-
Paech K., Webb P., Kuiper G.G., Nilsson S., Gustafsson J., Kushner P.J., Scanlan T.S. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science. 277:1997;1508-1510.
-
(1997)
Science
, vol.277
, pp. 1508-1510
-
-
Paech, K.1
Webb, P.2
Kuiper, G.G.3
Nilsson, S.4
Gustafsson, J.5
Kushner, P.J.6
Scanlan, T.S.7
-
25
-
-
0033959792
-
Disposition of radioactivity in Fischer 344 rats after single and multiple inhalation exposure to [(14)C] octamethylcyclotetrasiloxane ([140C]D94))
-
Plotzke K.P., Crofoot S., Ferdinandi E., Beattie J., Reitz R., McNett D., Meeks R. Disposition of radioactivity in Fischer 344 rats after single and multiple inhalation exposure to [(14)C] octamethylcyclotetrasiloxane ([140C]D94)). Drug Metab. Dispos. 28:2000;192-204.
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 192-204
-
-
Plotzke, K.P.1
Crofoot, S.2
Ferdinandi, E.3
Beattie, J.4
Reitz, R.5
McNett, D.6
Meeks, R.7
-
26
-
-
0025233835
-
Glucocorticoids inhibit estradiol-mediated uterine growth: Possible role of the uterine estradiol receptor
-
Rabin D., Johnson E., Brandon D., Liapi C., Chrousos G. Glucocorticoids inhibit estradiol-mediated uterine growth possible role of the uterine estradiol receptor . Biol. Reprod. 42:1990;74-80.
-
(1990)
Biol. Reprod.
, vol.42
, pp. 74-80
-
-
Rabin, D.1
Johnson, E.2
Brandon, D.3
Liapi, C.4
Chrousos, G.5
-
27
-
-
0037256556
-
Route-specific differences in distribution characteristics of octamethylcyclotetrasiloxane in rats: Analysis using PBPK models
-
Sarangapani R., Teeguarden J., Andersen M.E., Reitz R.H., Plotzke K.P. Route-specific differences in distribution characteristics of octamethylcyclotetrasiloxane in rats analysis using PBPK models . Toxicol. Sci. 71:2003;41-52.
-
(2003)
Toxicol. Sci.
, vol.71
, pp. 41-52
-
-
Sarangapani, R.1
Teeguarden, J.2
Andersen, M.E.3
Reitz, R.H.4
Plotzke, K.P.5
-
28
-
-
0001274194
-
Evaluation of octamethylcyclotetrasiloxane (D4) in a 2-generation reproductive toxicity study in rats
-
Stump D.G., Holson J.F., Kirkpatrick D.T., Reynolds V.L., Siddiqui W.H., Meeks R.G. Evaluation of octamethylcyclotetrasiloxane (D4) in a 2-generation reproductive toxicity study in rats. The Toxicologist. 54:2000;370.
-
(2000)
The Toxicologist
, vol.54
, pp. 370
-
-
Stump, D.G.1
Holson, J.F.2
Kirkpatrick, D.T.3
Reynolds, V.L.4
Siddiqui, W.H.5
Meeks, R.G.6
-
29
-
-
0035024595
-
Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway
-
Wade C.B., Robinson S., Shapiro R.A., Dorsa D.M. Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology. 142:2001;2336-2342.
-
(2001)
Endocrinology
, vol.142
, pp. 2336-2342
-
-
Wade, C.B.1
Robinson, S.2
Shapiro, R.A.3
Dorsa, D.M.4
-
30
-
-
0027749134
-
ICI 182,780: A pure antiestrogen that affects behaviors and energy balance in rats without acting in the brain
-
Wade G.N., Blaustein J.D., Gray J.M., Meredith J.M. ICI 182,780 a pure antiestrogen that affects behaviors and energy balance in rats without acting in the brain . Am. J. Physiol. 265:1993;R1392-R1398.
-
(1993)
Am. J. Physiol.
, vol.265
-
-
Wade, G.N.1
Blaustein, J.D.2
Gray, J.M.3
Meredith, J.M.4
-
31
-
-
0026395885
-
A potent specific pure antiestrogen with clinical potential
-
Wakeling A.E., Dukes M., Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res. 51:1991;3867-3873.
-
(1991)
Cancer Res.
, vol.51
, pp. 3867-3873
-
-
Wakeling, A.E.1
Dukes, M.2
Bowler, J.3
-
33
-
-
0033988417
-
Induction of rat hepatic drug metabolizing enzymes by dimethylcyclosiloxanes
-
Zhang J., Falany J.L., Xie X., Falany C.N. Induction of rat hepatic drug metabolizing enzymes by dimethylcyclosiloxanes. Chem. Biol. Interact. 124:2000;133-147.
-
(2000)
Chem. Biol. Interact.
, vol.124
, pp. 133-147
-
-
Zhang, J.1
Falany, J.L.2
Xie, X.3
Falany, C.N.4
|