Induction of rat hepatic drug metabolizing enzymes by dimethylcyclosiloxanes

Chemico-Biological Interactions

Volumn 124, Issue 2, 2000, Pages 133-147

  Zhang, Juan ^a   Falany, Josie L ^a   Xie, Xiaowei ^a   Falany, Charles N ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cytochrome P 450; Decamethylcyclopentasiloxane; Dimethylcyclosiloxane; Induction; Liver; Octamethyltetracyclosiloxane; Phenobarbital; R ats

Indexed keywords

CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; ETHOXYRESORUFIN DEETHYLASE; LIVER ENZYME; PENTOXYRESORUFIN DEALKYLASE; PHENOBARBITAL; SILOXANE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; FEMALE; IMMUNOREACTIVITY; LIVER MICROSOME; LIVER WEIGHT; MALE; NONHUMAN; RAT;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BIOCOMPATIBLE MATERIALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; MALE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SILOXANES; STEROID HYDROXYLASES;

EID: 0033988417     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(99)00153-2     Document Type: Article

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