GABAC receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level

Journal of Neurochemistry

Volumn 87, Issue 3, 2003, Pages 791-800

  Yang, Li ^a   Omori, Kyoko ^a   Omori, Koichiro ^a   Otani, Hitomi ^a   Suzukawa, Junko ^a   Inagaki, Chiyoko ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Ammonia intoxication; BAD phosphorylation; Cultured hippocampal neurons; GABAC receptors; Intracellular Ca2+ concentration

Indexed keywords

(1,2,5,6 TETRAHYDROPYRIDIN 4 YL)METHYLPHOSPHINIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 4 AMINOCROTONIC ACID; AMMONIA; BACLOFEN; BCL 2 ASSOCIATED DEATH PROMOTER; CASPASE 3; CASPASE 9; KT 5720; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MUSCIMOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHINIC ACID DERIVATIVE; PROTEIN BCL 2; SERINE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR; BAD PROTEIN, RAT; CALCIUM; CARRIER PROTEIN; GABA-C RECEPTOR; PROTEIN BAD;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE DEPOLARIZATION; ENZYME ACTIVATION; HIPPOCAMPUS; HYPERAMMONEMIA; IMMUNOCYTOCHEMISTRY; NERVE CELL CULTURE; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DRUG EFFECT; METABOLISM; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ANIMALIA;

AMMONIA; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CALCIUM; CARRIER PROTEINS; GABA AGONISTS; HIPPOCAMPUS; NEURONS; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTORS, GABA; SIGNAL TRANSDUCTION;

EID: 0142148221     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02069.x     Document Type: Article

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