Trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and (±)-trans-2-aminomethylcyclopropanecarboxylic acid ((±)-TAMP) can differentiate rat ρ3 from human ρ1 and ρ2 recombinant GABAC receptors

British Journal of Pharmacology

Volumn 135, Issue 4, 2002, Pages 883-890

  Vien, Jimmy ^a   Duke, Rujee K ^a   Mewett, Kenneth N ^a   Johnston, Graham A R ^a   Shingai, Ryuzo ^c   Chebib, Mary ^b  

^a University of Sydney   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c IWATE UNIVERSITY   (Japan)

Author keywords

Structure activity relationship profiles; Two electrode voltage clamp; Xenopus oocytes; Aminobutyric acid (GABA); 3 subunits

Indexed keywords

(1,2,5,6 TETRAHYDROPYRIDIN 4 YL)METHYLPHOSPHINIC ACID; (PIPERIDIN 4 YL)METHYLPHOSPHINIC ACID; 3 AMINOPROPANEPHOSPHONIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 IMIDAZOLEACETIC ACID; CIS 2 AMINOMETHYLCYCLOPROPANECARBOXYLIC ACID; CIS 4 AMINOCROTONIC ACID; GABOXADOL; MUSCIMOL; THIOMUSCIMOL; TRANS 2 AMINOMETHYLCYCLOPROPANECARBOXYLIC ACID; TRANS 3 AMINOCYCLOPENTANECARBOXYLIC ACID; TRANS 4 AMINO 2 METHYLBUT 2 ENOIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MEMBRANE ELECTROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; BUTYRIC ACID; BUTYRIC ACIDS; CARBOXYLIC ACIDS; CYCLOPROPANES; GABA AGONISTS; GABA ANTAGONISTS; HUMANS; ION CHANNELS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RATS; RECEPTORS, GABA; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0036188597     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704432     Document Type: Article

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