O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells

Experimental Hematology

Volumn 29, Issue 5, 2001, Pages 633-638

  Westerhof, G Robbin ^a   Down, Julian D ^b   Blokland, Irene ^a   Wood, Michelle ^c   Boudewijn, Adrie ^a   Watson, Amanda J ^c   McGown, Alan T ^c   Ploemacher, Rob E ^a   Margison, Geoffrey P ^c  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; BUSULFAN; CARMUSTINE; COMPLEMENTARY DNA; ALKYLATING AGENT; DRUG DERIVATIVE; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; O(6) BENZYLGUANINE; O(6)-BENZYLGUANINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; BURST FORMING UNIT E; CHO CELL; COLONY FORMING UNIT GM; COLONY FORMING UNIT S; CYTOTOXICITY; DNA ALKYLATION; DNA METHYLATION; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INACTIVATION; HEMATOPOIETIC STEM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ALKYLATION; ANIMAL; C57BL MOUSE; CELL LINE; CLONOGENIC ASSAY; COCULTURE; CRICETULUS; CYTOLOGY; DNA DAMAGE; DNA REPAIR; DRUG EFFECT; ERYTHROID PRECURSOR CELL; FIBROBLAST; GENETIC TRANSFECTION; HAMSTER; HUMAN; METABOLISM; STROMA CELL;

ALKYLATION; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BUSULFAN; CARMUSTINE; CELL LINE; CHO CELLS; COCULTURE TECHNIQUES; COLONY-FORMING UNITS ASSAY; CRICETINAE; CRICETULUS; DNA DAMAGE; DNA REPAIR; ERYTHROID PROGENITOR CELLS; FIBROBLASTS; GUANINE; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; STROMAL CELLS; TRANSFECTION;

EID: 0034743947     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(01)00631-2     Document Type: Article

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