-
1
-
-
0025070077
-
In vitro chemosensitivity testing of fotemustine (S10036), a new antitumor nitrosourea
-
Fichel,J.L., Formento,P and Etienne.M.C (1990) In vitro chemosensitivity testing of fotemustine (S10036), a new antitumor nitrosourea. Cancer Chem. Pharmacol., 25, 727-729.
-
(1990)
Cancer Chem. Pharmacol.
, vol.25
, pp. 727-729
-
-
Fichel, J.L.1
Formento, P.A.2
Etienne, M.C.3
-
2
-
-
0023688753
-
Pharmacocinetique clinique des nitrosourees
-
Bizzari,J.-P. and Deloffre,P. (1988) Pharmacocinetique clinique des nitrosourees. Bull. Cancer. 75, 813-818.
-
(1988)
Bull. Cancer.
, vol.75
, pp. 813-818
-
-
Bizzari, J.-P.1
Deloffre, P.2
-
3
-
-
0025109821
-
Final report of the french multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastasis
-
Jacquillat,C., Khayat,D., Banzet,P. et al. (1990) Final report of the french multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastasis. Cancer, 66, 1873-1878.
-
(1990)
Cancer
, vol.66
, pp. 1873-1878
-
-
Jacquillat, C.1
Khayat, D.2
Banzet, P.E.A.3
-
4
-
-
0025019373
-
Immunologic hemorrhagic pneumonia caused by isocyanates
-
Patterson,R., Nugent,K,M., Harris,K.E. and Eberle,M.E. (1990) Immunologic hemorrhagic pneumonia caused by isocyanates. Am. Rev. Resp. Dis., 141, 226-230.
-
(1990)
Am. Rev. Resp. Dis.
, vol.141
, pp. 226-230
-
-
Patterson, R.1
Nugent, K.M.2
Harris, K.E.3
Eberle, M.E.4
-
5
-
-
0022599533
-
Comparasive nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and chlorozotocin: Functional-structural correlations in the Fischer 344 rat
-
Kramer, R.A., Boyd, M.R. and Dees, J.H. (1986) Comparasive nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and chlorozotocin: functional-structural correlations in the Fischer 344 rat. Toxicol. Appl. Pharmacol., 82, 540-550.
-
(1986)
Toxicol. Appl. Pharmacol.
, vol.82
, pp. 540-550
-
-
Kramer, R.A.1
Boyd, M.R.2
Dees, J.H.3
-
6
-
-
0017345771
-
Active site specifc inactivation of chymotrypsin by cyclohexyl isocyanate formed during degradation of the carcinostatic 1-(2-chloroethyI)-1-nitrosourea
-
Babson,J., Reed,D. J. and Sinkey,M.A. (1977) Active site specifc inactivation of chymotrypsin by cyclohexyl isocyanate formed during degradation of the carcinostatic 1-(2-chloroethyI)-1-nitrosourea. Biochemistry, 16, 1584-4589.
-
(1977)
Biochemistry
, vol.16
, pp. 1584-4589
-
-
Babson, J.1
Reed, D.J.2
Sinkey, M.A.3
-
7
-
-
0026566053
-
Acute toxicity of methyl tsocyanate in rabbit: In vtiro and in vivo effects on rabbit erythrocyte membrane
-
Jeevaatnam,K. and Vaidyanathan,C.S. (1992) Acute toxicity of methyl tsocyanate in rabbit: in vtiro and in vivo effects on rabbit erythrocyte membrane Arch, Environ. Toxicol., 22, 300-304.
-
(1992)
Arch, Environ. Toxicol.
, vol.22
, pp. 300-304
-
-
Jeevaatnam, K.1
Vaidyanathan, C.S.2
-
8
-
-
0017865443
-
Inactivation of glutathione reductase by 2-chloroethylnitrosourea-derived isocyanates
-
Babson,J.R. and Reed,D.J. (1978) Inactivation of glutathione reductase by 2-chloroethylnitrosourea-derived isocyanates. Biochem. Biophys. Res. Commun., 83, 754-762.
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.83
, pp. 754-762
-
-
Babson, J.R.1
Reed, D.J.2
-
9
-
-
0027048785
-
Oxidative conversion by rat liver microsomes of 2-naphthyl isothiocyanate to 2-naphthyl isocyanate, a genotoxicant
-
Lee,M.-S. (1992) Oxidative conversion by rat liver microsomes of 2-naphthyl isothiocyanate to 2-naphthyl isocyanate, a genotoxicant. Chem. Res Toxicol., 5, 791-796.
-
(1992)
Chem. Res Toxicol.
, vol.5
, pp. 791-796
-
-
Lee, M.-S.1
-
10
-
-
0022347373
-
Effects of methyl isocyanate on the respiratory tract of rats
-
Nemery,B , Dinsdale,D., Sparrow,S. and Ray,D.E. (1985) Effects of methyl isocyanate on the respiratory tract of rats. Br. J. Ind. Med., 42, 799-805.
-
(1985)
Br. J. Ind. Med.
, vol.42
, pp. 799-805
-
-
Nemery, B.1
Dinsdale, D.2
Sparrow, S.3
Ray, D.E.4
-
11
-
-
0025993139
-
Mechanisms of immunotoxicity to isocyanates
-
Karol,M.H. and Jin,R. (1991) Mechanisms of immunotoxicity to isocyanates. Chem. Res Toxicol, 4, 503-509.
-
(1991)
Chem. Res Toxicol
, vol.4
, pp. 503-509
-
-
Karol, M.H.1
Jin, R.2
-
12
-
-
0026502947
-
Altered lung function in rats after subacute exposure to n-butyl isocyanate
-
Pauluhn,J. and Eben,A, (1992) Altered lung function in rats after subacute exposure to n-butyl isocyanate. Arch. Toxicol., 66, 118-125.
-
(1992)
Arch. Toxicol.
, vol.66
, pp. 118-125
-
-
Pauluhn, J.1
Eben, A.2
-
13
-
-
0027501997
-
Activity and unexpected lungtoxicity of the sequential administration of two alkylating agents-dacarbazine and fotemustine-in patients with melanoma
-
Gerard,B., Aamdal,S., Lee,S.-M., Leyvraz,S., Lucas,C., D'Incalci,M. and Bizzari,J.P (1993) Activity and unexpected lungtoxicity of the sequential administration of two alkylating agents-dacarbazine and fotemustine-in patients with melanoma. Eur. J. Cancer, 29, 711-719.
-
(1993)
Eur. J. Cancer
, vol.29
, pp. 711-719
-
-
Gerard, B.1
Aamdal, S.2
Lee, S.-M.3
Leyvraz, S.4
Lucas, C.5
D'Incalci, M.6
Bizzari, J.P.7
-
14
-
-
0019235729
-
Chronic toxicity of cytostatic N-nitroso(2-chloroethyl)-ureas after repeated intraveneous application in rats
-
Holmstedt et al. (eds)
-
Eisenbrand,G. and Habs,M. (1980) Chronic toxicity of cytostatic N-nitroso(2-chloroethyl)-ureas after repeated intraveneous application in rats. In Holmstedt et al. (eds), Mechanisms of toxicity and hazard evaluation, pp. 273-278.
-
(1980)
Mechanisms of Toxicity and Hazard Evaluation
, pp. 273-278
-
-
Eisenbrand, G.1
Habs, M.2
-
15
-
-
0024412738
-
Effects of the new nitrosourea derivative fotemustine on the glutathione reductase activity in rat tissues in vivo and in isolated rat hepatocytes
-
Boutin,J.A., Norbreck,K., Moldeus,P., Genton,A., Paraire,M., Bizzari,J.P., Lavielle,G. and Cudennec,C.A. (1989) Effects of the new nitrosourea derivative fotemustine on the glutathione reductase activity in rat tissues in vivo and in isolated rat hepatocytes. Eur J. Cancer Clin. Oncol., 25, 1311-1316.
-
(1989)
Eur J. Cancer Clin. Oncol.
, vol.25
, pp. 1311-1316
-
-
Boutin, J.A.1
Norbreck, K.2
Moldeus, P.3
Genton, A.4
Paraire, M.5
Bizzari, J.P.6
Lavielle, G.7
Cudennec, C.A.8
-
16
-
-
0025062053
-
The mechanism of action of the nitrosourea anti-tumor drugs on thioredoxin reductase, glutathione reductase and nbonucleotide reductase
-
Schallreuter,K.U., Gleason,FK. and Wood,J.M. (1990) The mechanism of action of the nitrosourea anti-tumor drugs on thioredoxin reductase, glutathione reductase and nbonucleotide reductase. Btochtm. Biophys. Acta. 1054, 14-20.
-
(1990)
Btochtm. Biophys. Acta.
, vol.1054
, pp. 14-20
-
-
Schallreuter, K.U.1
Gleason, F.K.2
Wood, J.M.3
-
17
-
-
0028221112
-
Chemical and glutathione conjugation-related degradation of fotemustine: Formation and characterization of a glutathione conjugate of diethyl(1-isocyanatoethyl) phosphorate a reactive metabolite of fotemustine
-
Brakenhoff,J.P.G., Commandeur,J.N.M., de Kanter,F.J.J., van Baar,B.L.M., Luijten,W.C.M.M. and Vermeulen,N.P.E. (1994) Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl(1-isocyanatoethyl) phosphorate a reactive metabolite of fotemustine. Chem. Res. Toxicol., 7, 380-389.
-
(1994)
Chem. Res. Toxicol.
, vol.7
, pp. 380-389
-
-
Brakenhoff, J.P.G.1
Commandeur, J.N.M.2
De Kanter, F.J.J.3
Van Baar, B.L.M.4
Luijten, W.C.M.M.5
Vermeulen, N.P.E.6
-
18
-
-
0027497277
-
Identification and quantitative determination of glutathione-related urinary metabolites of fotemustine, a new anti-cancer agent
-
Brakenhoff,J.P.G., Commandeur,J.N.M., Lamorée,M.H., Dubelaar,A.C., van Baar,B.L.M., Lucas,C. and Vermeulen,N.P.E. (1993) Identification and quantitative determination of glutathione-related urinary metabolites of fotemustine, a new anti-cancer agent. Xenobiotica, 23, 935-947.
-
(1993)
Xenobiotica
, vol.23
, pp. 935-947
-
-
Brakenhoff, J.P.G.1
Commandeur, J.N.M.2
Lamorée, M.H.3
Dubelaar, A.C.4
Van Baar, B.L.M.5
Lucas, C.6
Vermeulen, N.P.E.7
-
19
-
-
0027172880
-
Studies on the metabolic fate of caracemide, an experimental antitumor agent in the rat. Evidence for the release of methyl isocyanate in vivo
-
Slatter,J.G., Davis,M.R., Han,D-H., Pearson,P.G. and Baillie,T.A. (1993) Studies on the metabolic fate of caracemide, an experimental antitumor agent in the rat. Evidence for the release of methyl isocyanate in vivo. Chem. Res. Toxicol., 6, 335-340.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 335-340
-
-
Slatter, J.G.1
Davis, M.R.2
Han, D.-H.3
Pearson, P.G.4
Baillie, T.A.5
-
20
-
-
0026574496
-
Mechanism of glutathione-mediated DNA damage by the antineoplastic agent 1,3-bis(2-chloroethyl)-N-nitrosourea
-
Stahl,W., Lenhardt,S., Przybylski,M. and Eisenbrand,G. (1992) Mechanism of glutathione-mediated DNA damage by the antineoplastic agent 1,3-bis(2-chloroethyl)-N-nitrosourea Chem. Res. Toxtcol., 5, 106-109.
-
(1992)
Chem. Res. Toxtcol.
, vol.5
, pp. 106-109
-
-
Stahl, W.1
Lenhardt, S.2
Przybylski, M.3
Eisenbrand, G.4
-
21
-
-
15844429047
-
-
doctoral thesis, department of food chemistry and environmental toxicology, Kaiserslautern, Germany
-
Stahl,W. (1987) Untersuchungen zur reaction von 2-chloroethylnitrosohamstoffen doctoral thesis, department of food chemistry and environmental toxicology, Kaiserslautern, Germany.
-
(1987)
Untersuchungen zur Reaction von 2-chloroethylnitrosohamstoffen
-
-
Stahl, W.1
-
22
-
-
0017794351
-
Measurement of substrate and inhibitor binding to microsonal cytochrome P450
-
Jefcoate,C.R. (1978) Measurement of substrate and inhibitor binding to microsonal cytochrome P450. Method Enzymol, 52, 258-279.
-
(1978)
Method Enzymol
, vol.52
, pp. 258-279
-
-
Jefcoate, C.R.1
-
23
-
-
0024842717
-
Effect of adriamycin on the activities of Superoxide dismutase, glutathione peroxidase and catalase in tissues of mice
-
Sazuka,Y., Tanizawa,H. and Takino,Y. (1989) Effect of adriamycin on the activities of Superoxide dismutase, glutathione peroxidase and catalase in tissues of mice. Jpn J. Cancer. Res., 80, 89-94
-
(1989)
Jpn J. Cancer. Res.
, vol.80
, pp. 89-94
-
-
Sazuka, Y.1
Tanizawa, H.2
Takino, Y.3
-
24
-
-
0014108436
-
Studies on quantitative and qualitative characterization of erythrocyte glutathione peroxidase
-
Paglia,D.E. and Valentine,W.N. (1967) Studies on quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab. Clin. Med., 70, 158-169.
-
(1967)
J Lab. Clin. Med.
, vol.70
, pp. 158-169
-
-
Paglia, D.E.1
Valentine, W.N.2
-
25
-
-
0016210428
-
Purification of the crystalline enzyme from erythrocytes
-
Worthington,D.J. and Rosemeyer,M.A. (1974) Purification of the crystalline enzyme from erythrocytes. Eur. J. Biochem., 48, 167-177.
-
(1974)
Eur. J. Biochem.
, vol.48
, pp. 167-177
-
-
Worthington, D.J.1
Rosemeyer, M.A.2
-
26
-
-
0016275313
-
The first enzymatic step in mercapturic acid formation
-
Habig,W.H., Pabst,M.J. and Jacoby,W.B (1974) The first enzymatic step in mercapturic acid formation. J. Biol. Chem., 249, 7130-7139.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jacoby, W.B.3
-
27
-
-
0024471521
-
Effects of thiols on lipid peroxidation in rat liver microsomes
-
Haenen,G.R.M.M., Vermeulen,NP.E., Timmerman,H. and Bast,A. (1989) Effects of thiols on lipid peroxidation in rat liver microsomes. Chem. Biol Interactions, 71, 201-212.
-
(1989)
Chem. Biol Interactions
, vol.71
, pp. 201-212
-
-
Haenen, G.R.M.M.1
Vermeulen, N.P.E.2
Timmerman, H.3
Bast, A.4
-
28
-
-
0021058742
-
-
Nagelkerke,J.F., Barto,K.P. and van Berkel,T.J.C. (1983) J. Biol. Chem., 258, 12221-12227.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 12221-12227
-
-
Nagelkerke, J.F.1
Barto, K.P.2
Van Berkel, T.J.C.3
-
29
-
-
0023182733
-
-
van de Straat,R., de Vries,J., Debets,A.J.J. and Vermeulen,N.P.E. (1987) Biochem. Pharmacol., 36, 2065-2070.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2065-2070
-
-
Van De Straat, R.1
De Vries, J.2
Debets, A.J.J.3
Vermeulen, N.P.E.4
-
30
-
-
0023691709
-
Determination of glutathione in biological material by flow-injection analysis using an enzyme recycling reaction
-
Redegeld,F.A.M., van Opstal,M.A.J., Houdkamp,E. and van Bennekom,W.P. (1988) Determination of glutathione in biological material by flow-injection analysis using an enzyme recycling reaction. Analyt. Biochem., 174, 489-495
-
(1988)
Analyt. Biochem.
, vol.174
, pp. 489-495
-
-
Redegeld, F.A.M.1
Van Opstal, M.A.J.2
Houdkamp, E.3
Van Bennekom, W.P.4
-
31
-
-
0022537776
-
Glutathione- and cysteine-mediated cytotoxicity of allyl and benzyl isothiocyanate
-
Bruggeman,I.M., TemminkJ,H.M. and van Bladeren,P.J. (1986) Glutathione- and cysteine-mediated cytotoxicity of allyl and benzyl isothiocyanate. Toxicol. Appl Pharmacol, 83, 349-359.
-
(1986)
Toxicol. Appl Pharmacol
, vol.83
, pp. 349-359
-
-
Bruggeman, I.M.1
Temmink, J.H.M.2
Van Bladeren, P.J.3
-
32
-
-
0025963771
-
Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities
-
Slatter,J.G., Rashed,M.S., Pearson,P.G., Han,D.-H. and Baillie,T.A. (1991) Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities. Chem. Res. Toxicol., 4, 157-161.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 157-161
-
-
Slatter, J.G.1
Rashed, M.S.2
Pearson, P.G.3
Han, D.-H.4
Baillie, T.A.5
-
33
-
-
0015069483
-
Potassium cyanate as an inhibitor of the sickling of erythrocytes in vitro
-
Cerami,A. and Manning,J.M. (1971) Potassium cyanate as an inhibitor of the sickling of erythrocytes in vitro. Proc. Natl Acad. Sci. USA, 68, 1180-1183.
-
(1971)
Proc. Natl Acad. Sci. USA
, vol.68
, pp. 1180-1183
-
-
Cerami, A.1
Manning, J.M.2
-
34
-
-
0024438921
-
Three models of free radical-induced cell injury
-
Comporti,M. (1989) Three models of free radical-induced cell injury. Chem. -Biol. Interactions, 72, 1-56.
-
(1989)
Chem. -Biol. Interactions
, vol.72
, pp. 1-56
-
-
Comporti, M.1
-
35
-
-
0023201205
-
Glutathione depleting agents and lipid peroxidation
-
Comporti,M. (1987) Glutathione depleting agents and lipid peroxidation. Chem. Phys. Lipids, 45, 143-169.
-
(1987)
Chem. Phys. Lipids
, vol.45
, pp. 143-169
-
-
Comporti, M.1
-
36
-
-
0021679739
-
Cytochrome P-450 and glutathione, what is the significance of their interrelationship in lipid peroxidation
-
Bast,A. and Haenen,G.R.M.M. (1984) Cytochrome P-450 and glutathione, what is the significance of their interrelationship in lipid peroxidation. Trends Biochem. Sci, 9, 510-513.
-
(1984)
Trends Biochem. Sci
, vol.9
, pp. 510-513
-
-
Bast, A.1
Haenen, G.R.M.M.2
-
40
-
-
0022217758
-
2+ sequestration by toxic agents
-
2+ sequestration by toxic agents. Biochem,. Pharmacol., 34, 3717-3723.
-
(1985)
Biochem,. Pharmacol.
, vol.34
, pp. 3717-3723
-
-
Thor, H.1
Hartzell, P.2
Svensson, S.A.3
Orrenius, S.4
Mirabelli, F.5
Marinoni, V.6
Bellomo, G.7
-
41
-
-
0023221710
-
Cyclandelate as a calcium modulating agent in rat cerebral cortex
-
Bast,A., Leurs,R. and Timmerman,H. (1989) Cyclandelate as a calcium modulating agent in rat cerebral cortex. Drugs, 33, 67-74.
-
(1989)
Drugs
, vol.33
, pp. 67-74
-
-
Bast, A.1
Leurs, R.2
Timmerman, H.3
-
42
-
-
0019322029
-
The glutathione peroxidase activity of the glutathione-S-transferases
-
Prohaska,J.R. (1980) The glutathione peroxidase activity of the glutathione-S-transferases. Biochim. Biophys. Acta. 611, 157-174.
-
(1980)
Biochim. Biophys. Acta.
, vol.611
, pp. 157-174
-
-
Prohaska, J.R.1
-
43
-
-
0023554154
-
Phase I clinical study of the amino acid-linked nitrosourea, S 10036, administered on a weekly schedule
-
Khayat,D., Lokiec.F., Bizzari,J.P., Weil,M., Meeus,L., Sellami,M., Rouesse,J., Banzet,P. and Jacquillat,C. (1987) Phase I clinical study of the amino acid-linked nitrosourea, S 10036, administered on a weekly schedule. Cancer Res., 47, 6782-6785.
-
(1987)
Cancer Res.
, vol.47
, pp. 6782-6785
-
-
Khayat, D.1
Lokiec, F.2
Bizzari, J.P.3
Weil, M.4
Meeus, L.5
Sellami, M.6
Rouesse, J.7
Banzet, P.8
Jacquillat, C.9
-
44
-
-
0029008428
-
Enzymes and transport systems involved in the formation and dispostion of glutathione-S-conjugates
-
Commandeur,J.N.M., Stijntjes,G.J. and Vermeulen,N.P.E. (1995) Enzymes and transport systems involved in the formation and dispostion of glutathione-S-conjugates. Pharmacol. Rev., 47. 271-336.
-
(1995)
Pharmacol. Rev.
, vol.47
, pp. 271-336
-
-
Commandeur, J.N.M.1
Stijntjes, G.J.2
Vermeulen, N.P.E.3
-
45
-
-
0028351532
-
Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate
-
Jochheim,C.M. and Baillie,T.A. (1994) Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate. Biochem. Pharmacol.. 48, 1197.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1197
-
-
Jochheim, C.M.1
Baillie, T.A.2
-
46
-
-
0028060034
-
Effects of carabamate thioester derivatives of methyl and 2-chloroelhyl isocyanate on glutathione levels and glutathione reductase activities in tha rat
-
Kassahun,A. et al. (1994) Effects of carabamate thioester derivatives of methyl and 2-chloroelhyl isocyanate on glutathione levels and glutathione reductase activities in tha rat. Biochem. Pharmacol., 48, 587.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 587
-
-
Kassahun, A.1
-
47
-
-
0018757929
-
Mechanism of inhibition of red blood cell glutathione reductase activity by BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea)
-
Shinohara,K. and Tanaka,K.R. (1979) Mechanism of inhibition of red blood cell glutathione reductase activity by BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea). Clin. Chim. Acta, 92, 147-152.
-
(1979)
Clin. Chim. Acta
, vol.92
, pp. 147-152
-
-
Shinohara, K.1
Tanaka, K.R.2
-
48
-
-
0025800184
-
Comparative study on the influence of two 2-chloroethylnitrosoureas with different carbamoylating potential towards glutathione and glutathione related enzyms in different organs in the rat
-
Stahl,W. and Eisenbrand,G. (1991) Comparative study on the influence of two 2-chloroethylnitrosoureas with different carbamoylating potential towards glutathione and glutathione related enzyms in different organs in the rat. Free Rod. Res. Commun., 14, 271-278.
-
(1991)
Free Rod. Res. Commun.
, vol.14
, pp. 271-278
-
-
Stahl, W.1
Eisenbrand, G.2
-
49
-
-
0002814999
-
Carbamoylating activity of nitrosoureas
-
Prestakyo,A.W. et al (eds), Academic Press. New York
-
Kann,H.E. (1981) Carbamoylating activity of nitrosoureas. In Prestakyo,A.W. et al (eds), Nitrosoureas: current status and new developements. Academic Press. New York, pp. 95-105.
-
(1981)
Nitrosoureas: Current Status and New Developements
, pp. 95-105
-
-
Kann, H.E.1
-
50
-
-
0022356928
-
Chemical structure of carbamoylating groups and their relationships to bone marrow toxicity and antiglioma activity of bifunctional alkylating and carbamoylating agents
-
Ali-Osman,F., Ginlin,J., Berger,M., Murphy,M. and Rosenblum,M. (1985) Chemical structure of carbamoylating groups and their relationships to bone marrow toxicity and antiglioma activity of bifunctional alkylating and carbamoylating agents. Cancer Res., 45. 4185-4191.
-
(1985)
Cancer Res.
, vol.45
, pp. 4185-4191
-
-
Ali-Osman, F.1
Ginlin, J.2
Berger, M.3
Murphy, M.4
Rosenblum, M.5
-
51
-
-
0023839663
-
Inhibition of human glutattuone reductase by the nitrosourea drugs 1.3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea
-
Karplus,P.A., Krauth-Siegel,R.L., Schirmer,R.H. and Schultz,G.E. (1988) Inhibition of human glutattuone reductase by the nitrosourea drugs 1.3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. Eur. J .Biochem., 171. 193-198.
-
(1988)
Eur. J .Biochem.
, vol.171
, pp. 193-198
-
-
Karplus, P.A.1
Krauth-Siegel, R.L.2
Schirmer, R.H.3
Schultz, G.E.4
-
52
-
-
0023217298
-
The effect of a novel taurine nitrosourea, 1-(2-chloroethyl)-3-[2-(dimethylaminosulfonyl)ethyl]-1-nitrosourea (TCNU) on cytotoxicity, DNA crosslinking and glutathione reductase in lung carcinoma cell lines
-
Tew,K.D., Dean,S.W. and Gibson,N.W. (1987) The effect of a novel taurine nitrosourea, 1-(2-chloroethyl)-3-[2-(dimethylaminosulfonyl)ethyl]-1-nitrosourea (TCNU) on cytotoxicity, DNA crosslinking and glutathione reductase in lung carcinoma cell lines. Cancer Chem. Pharmacol., 19, 291-295.
-
(1987)
Cancer Chem. Pharmacol.
, vol.19
, pp. 291-295
-
-
Tew, K.D.1
Dean, S.W.2
Gibson, N.W.3
-
53
-
-
0027275385
-
Role of lipid peroxidauon in impairment of mitochondrial function at complex I by methylisocyanate treatment of rats in vivo
-
Jeevaratnam,K., Vidya,S. and Vaidyanathan,C.S. (1993) Role of lipid peroxidauon in impairment of mitochondrial function at complex I by methylisocyanate treatment of rats in vivo. Biochem. Mol. Biol. Int., 30, 411-417.
-
(1993)
Biochem. Mol. Biol. Int.
, vol.30
, pp. 411-417
-
-
Jeevaratnam, K.1
Vidya, S.2
Vaidyanathan, C.S.3
-
54
-
-
0020615123
-
Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)
-
Meredith,M.J. and Reed,D.J. (1983) Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) Biochem. Pharmacol., 32, 1383-1388.
-
(1983)
Biochem. Pharmacol.
, vol.32
, pp. 1383-1388
-
-
Meredith, M.J.1
Reed, D.J.2
-
55
-
-
0012005411
-
Formation and protection against toxic reactive intermediates
-
Tesla,B., Kyburz,E., Fuhrer,W. and Giger,R. (eds), Verlag Helvetica Chimica Acta, Basel, Switzerland
-
Vermeulen,N.P.E., den Kelder,D.-O. and Commandeur,J.K.M. (1993) Formation and protection against toxic reactive intermediates. In Tesla,B., Kyburz,E., Fuhrer,W. and Giger,R. (eds), Perspectives in medicinal chemisiry. Verlag Helvetica Chimica Acta, Basel, Switzerland, pp. 573-593.
-
(1993)
Perspectives in Medicinal Chemisiry
, pp. 573-593
-
-
Vermeulen, N.P.E.1
Den Kelder, D.-O.2
Commandeur, J.K.M.3
|