Caspase-3-mediated cleavage of Rad9 during apoptosis

Oncogene

Volumn 22, Issue 41, 2003, Pages 6340-6346

  Lee, Michael W ^a,b   Hirai, Itaru ^a,b   Wang, Hong Gang ^a,b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Apoptosis; Caspase 3; Cell cycle checkpoint; DNA damage; Rad9

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; MUTANT PROTEIN; PROTEIN; PROTEIN BCL XL; PROTEIN RAD9; STAUROSPORINE; UNCLASSIFIED DRUG; BCL2L1 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP6 PROTEIN, HUMAN; CASPASE; CASPASE 6; CELL CYCLE PROTEIN; PROTEIN BCL 2; PROTEIN BCL X;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CELL CYCLE; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; GENE TRANSLOCATION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; CELL STRAIN U937; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY;

MINK CELL FOCUS-FORMING VIRUS;

APOPTOSIS; BCL-X PROTEIN; CASPASE 3; CASPASE 6; CASPASES; CELL CYCLE PROTEINS; DNA DAMAGE; HUMANS; MUTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; U937 CELLS;

EID: 0142103820     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206729     Document Type: Article

References (27)

1. Aravind L, Walker DR and Koonin EV. (1999). Nucleic Acids Res., 27, 1223-1242.
2. Burtelow MA, Roos-Mattjus PM, Rauen M, Babendure JR and Karnitz LM. (2001). J. Biol. Chem., 276, 25903-25909.
3. Caspari T and Carr AM. (2002). Curr. Biol., 12, R105-R107.
4. Chen MJ, Lin YT, Lieberman HB, Chen G and Lee EY. (2001). J. Biol. Chem., 276, 16580-16586.
5. Earnshaw WC, Martins LM and Kaufmann SH. (1999). Annu. Rev. Biochem., 68, 383-424.
6. Green DR and Reed JC. (1998). Science, 281, 1309-1312.
7. Hartwell LH and Kastan MB. (1994). Science, 266, 1821-1828.
8. Hayashi K, Kuniyasu H, Oue N, Shigeishi H, Kuraoka K, Nakayama H and Yasui W. (2002). Pathobiology, 70, 40-46.
9. Hirai I and Wang HG. (2002). J. Biol. Chem., 277, 25722-25727.
10. Komatsu K, Hopkins KM, Lieberman HB and Wang H-G. (2000a). FEBS Lett., 481, 122-126.
11. Komatsu K, Miyashita T, Hang H, Hopkins KM, Zheng W, Cuddeback S, Yamada M, Lieberman HB and Wang HG. (2000b). Nat. Cell Biol., 2, 1-6.
12. Nicholson DW. (1999). Cell Death Differ., 6, 1028-1042.
13. O'Connell MJ, Walworth NC and Carr AM. (2000). Trends Cell Biol., 10, 296-303.
14. Reed JC. (1998). Oncogene, 17, 3225-3236.
15. Salvesen GS and Dixit VM. (1997). Cell, 91, 443-446.
16. St Onge RP, Besley BD, Park M, Casselman R and Davey S. (2001). J. Biol. Chem., 276, 41898-41905.
17. St Onge RP, Udell CM, Casselman R and Davey S. (1999). Mol. Biol. Cell, 10, 1985-1995.
18. Stennicke HR and Salvesen GS. (1997). J. Biol. Chem., 272, 25719-25723.
19. Thornberry N, Rano T, Peterson E, Rasper D, Timkey T, Garcia-Calvo M, Houtzager V, Nordstrom P, Roy S, Vaillancourt J, Chapman K and Nicholson D. (1997). J. Biol. Chem., 212, 17907-17911.
20. Tsurimoto T. (1999). Front Biosci., 4, D849-D858.
21. Venclovas C and Thelen MP. (2000). Nucleic Acids Res., 28, 2481-2493.
22. Volkmer E and Karnitz LM. (1999). J. Biol. Chem., 274, 567-570.
23. Wahl GM and Carr AM. (2001). Nat. Cell Biol., 3, E277-E286.
24. Wang H-G and Reed JC. (1998). Histol. Histopathol., 13, 521-530.
25. Yoshida K, Komatsu K, Wang HG and Kufe D. (2002). Mol. Cell. Biol., 22, 3292-3300.
26. Zhou BB and Elledge SJ. (2000). Nature, 408, 433-439.
27. Zimmermann KC, Bonzon C and Green DR. (2001). Pharmacol Ther., 92, 57-70.