Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 21, 2003, Pages 12337-12342

  De Candia, Paola ^a   Solit, David B ^a   Giri, Dilip ^b   Brogi, Edi ^a   Siegel, Peter M ^a   Olshen, Adam B ^a   Muller, William J ^c   Rosen, Neal ^a   Benezra, Robert ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Geldanamycin

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; ANTINEOPLASTIC ANTIBIOTIC; HEAT SHOCK PROTEIN 90; UNCLASSIFIED DRUG;

ADVANCED CANCER; ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST DISEASE; BREAST TUMOR; CONTROLLED STUDY; HISTOLOGY; IMMUNOBLOTTING; MOUSE; NONHUMAN; ONCOGENE NEU; PHENOTYPE; PRIORITY JOURNAL; TUMOR GROWTH;

ANIMALS; ANTIGENS, NEOPLASM; BENZOQUINONES; FEMALE; GENES, ERBB-2; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LACTAMS, MACROCYCLIC; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; PHENOTYPE; RIFABUTIN; TRANSCRIPTION FACTORS; UP-REGULATION;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS;

EID: 0142027766     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2031337100     Document Type: Article

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