IL-11 Enhances Survival and Decreases TNF Production after Radiation-Induced Thoracic Injury

Journal of Immunology

Volumn 157, Issue 4, 1996, Pages 1705-1710

  Redlich, Carrie A ^a   Gao, Xin ^a   Rockwell, Sara ^a   Kelley, Marianne ^a   Elias, Jack A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 11; MESSENGER RNA; RECOMBINANT PROTEIN; RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER STEM CELL; CELL LINE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG TUMOR; METASTASIS; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY; SUBCUTANEOUS DRUG ADMINISTRATION; THORAX INJURY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-11; LUNG NEOPLASMS; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; RADIATION INJURIES, EXPERIMENTAL; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; SPECIFIC PATHOGEN-FREE ORGANISMS; THORACIC INJURIES; TUMOR NECROSIS FACTOR-ALPHA; TUMOR STEM CELLS;

EID: 0030586606     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Ward, W. F., and Y. T. Kim. 1989. Radiation-induced pulmonary fibrosis. In CRC Handbook of Animal Models of Pulmonary Disease, Vol. 1. J. O. Cantor, ed. CRC Press, Boca Raton, pp. 165-195.
2. McDonald, S., P. Rubin, T. L. Phillips, and L. B. Marks. 1995. Injury to the lung from cancer therapy: clinical syndromes, measurable endpoints, and potential scoring systems. Int. J. Radiat. Oncol. Biol. Phys. 31:1187.
3. Morgan, G. W., and S. N. Breit. 1995. Radiation and the lung: a reevaluation of the mechanisms mediating pulmonary injury. Int. J. Radiat. Oncol. Biol. Phys. 31:361.
4. Du, X. X., and D. A. Williams. 1994. Interleukin-11: a multifunctional growth factor derived from the hematopoietic microenvironment. Blood 83:2023.
5. Paul, S. R., F. Bennett, J. A. Calvetti, K. Kelleher, C. R. Wood, R. M. O'Hara, A. C. Leary, B. Sibley, S. C. Clark, D. A. Williams, and Y. C. Yang. 1990. Molecular cloning of a cDNA encoding IL-11, a stromal cell-derived lymphopoietic cytokine. Proc. Nat. Acad. Sci. USA 87:7512.
6. Zhang, X., J. J. Gu, Z. Y. Lu, K. Yasukawa, G. D. Yancopoulos, K. Turner, M. Shoyab, T. Taga, T. Kishimoto, R. Bataille, and B. Klein. 1994. Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin are growth factors for human myeloma cell lines using the interleukin 6 signal transducer GP130. J. Exp. Med. 177:1337.
7. Yin, T. G., P. Schendel, and Y. C. Yang. 1992. Enhancement of in vitro and in vivo antigen-specific antibody responses by IL-11. J. Exp. Med. 175:211.
8. Maier, R., V. Ganu, and M. Lotz. 1993. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases. J. Biol. Chem. 268:21527.
9. Girasole, G., G. Passeri, R. L. Jilka, and S. C. Manolagas. 1994. Interleukin-11: a new cytokine critical for osteoclast development. J. Clin. Invest. 93:1516.
10. Du, X. X., C. M. Doerschuk, A. Orazi, and D. A. Williams. 1994. A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy. Blood 83:33.
11. Keith, J. C., L. Albert, S. T. Sonis, C. J. Pfeiffer, and R. G. Schaub. 1994. IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology. Stem Cells. 12 (Suppl. 1):79-89.
12. Elias, J. A., T. Zheng, N. L. Whiting, T. K. Trow, W. W. Merrill, R. Zitnik, P. Ray, and E. M. Alderman. 1994. Interleukin-1 and transforming growth factor-β regulation of fibroblast-derived interleukin-11. J. Immunol. 152:2421.
13. Elias, J. A., T. Zheng, O. Einarsson, M. Landry, T. Trow, N. Rebert, and J. Panuska. 1994. Epithelial interleukin-11: regulation by cytokines, respiratory syncytial virus and retinoic acid. J. Biol. Chem. 269:22261.
14. Zheng, T., M. Nathanson, and J. A. Elias. 1994. Histamine augments cytokine-stimulated IL-11 production by human lung fibroblasts. J. Immunol. 153:4742.
15. Einarsson, O., G. P. Geba, Z. Zhu, M. Landry, and J. A. Elias. 1996. IL-11 stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J. Clin. Invest. 97:915.
16. Rockwell, S., C. G. Irvin, and M. Nierenburg. 1986. Effect of a perfluorochemical emulsion on the development of artificial lung metastases in mice. Clin. Exp. Metastasis 4:45.
17. Rockwell, S., and M. Kelley. 1989. Radiation enhancement of lung nodule formation in mice is not potentiated by treatment with a perfluorochemical emulsion and carbogen. Radiother. Oncol. 14:49.
18. Rockwell, S. 1987. Maintenance of tumor systems and appropriate treatment techniques for experimental tumors. In Rodent Tumors in Experimental Cancer Therapy. R. F. Kallman, ed. Plenum Press, New York, pp. 29-36.
19. Chomaczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
20. Elias, J. A., and V. Lentz. 1990. IL-1 and tumor necrosis factor synergistically stimulate fibroblast IL-6 production and stabilize IL-6 messenger RNA. J. Immunol. 145:161.
21. Emami, B., J. Lyman, A. Brown, L. Coia, M. Goitein, J. E. Munzenrider, B. Shank, L. J. Solin, and M. Wesson. 1991. Tolerance of normal tissues to therapeutic irradiation. Int. J. Radiat. Oncol. Biol. Phys. 21:109.
22. Tracey, K. J., and A. Cerami. 1990. The biology of cachectin/tumor necrosis factor. In Growth Factors, Differentiation Factors, and Cytokines. A. Habenicht, ed. Springer-Verlag, Berlin Heidelberg, pp. 356-365.
23. Remick, D. G. 1993. Lung and gut injury induced by tumour necrosis factor. Res. Immunol. 144:326.
24. Remick, D. G., and S. L. Kunkel. 1993. Pathophysiologic alterations induced by tumor necrosis factor. Int. Rev. Exp. Pathol. 34:7.
25. Kureshi, S. A., F. M. Hofman, J. H. Schneider, L. S. Chin, M. L. J. Apuzzo, and D. R. Hinton. 1994. Cytokine expression in radiation-induced delayed cerebral injury. Neurosurgery 35:822.
26. Girinsky, T. A., M. Pallardy, E. Comoy, T. Benassi, R. Roger, G. Ganem, J. M. Cosset, G. Socie, and H. Magdelenat. 1994. Peripheral blood corticotropin-releasing factor, adrenocorticotropic hormone and cytokine (interleukin beta, interleukin 6, tumor necrosis factor alpha) levels of high- and low-dose total-body irradiation in humans. Radiat. Res. 139:360.
27. Hallahan, D. E., D. R. Spriggs, M. A. Beckett, D. W. Kufe, and R. R. Weichselbaum. 1989. Increased tumor necrosis factor α mRNA after cellular exposure to ionizing radiation. Proc. Nat. Acad. Sci. USA 86:10104.
28. Iwamoto, K. S., and W. H. McBride. 1994. Production of 13-hydroxyoctadecadienoic acid and tumor necrosis factor-α by murine peritoneal macrophages in response to irradiation. Radiat Res. 139:103.
29. Chiang, C. S., and W. H. McBride. 1991. Radiation enhances tumor necrosis factor α production by murine brain cells. Brain Res. 566:265.
30. Sherman, M. L., R. Datta, D. E. Hallahan, R. R. Weichselbaum, and D. W. Kufe. 1991. Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes. J. Clin. Invest. 87: 1794.
31. Bortin, M. M., H. E. M. Kay, R. P. Gale, and A. Rimm. 1982. Factors associated with interstitial pneumonitis after bone marrow transplantation for acute leukemia. Lancet 8269:437.
32. Pierce, S. M., A. Recht, T. I. Lingos, A. Abner, F. Vincini, B. Silver, A. Herzog, and J. R. Harris. 1992. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int. J. Radiat. Oncol. Biol. Phys. 23:915.
33. Price, A., W. J. Jack, G. R. Kerr, and A. Rodger. 1990. Acute radiation pneumonitis after postmastectomy irradiation: effect of fraction size. Clin. Oncol. 2:224.
34. Neta, R., J. J. Oppenheim, R. D. Schreiber, R. Chizzonite, G. D. Ledney, and T. J. MacVittie. 1991. Role of cytokines (interleukin 1, tumor necrosis factor, and transforming growth factor beta) in natural and lipopolysaccharide-enchanced radioresistance. J. Exp. Med. 173:1177.
35. Dalmau, S. R., C. S. Freitas, and D. G. Tabak. 1993. Interleukin-1 and tumor necrosis factor-alpha as radio- and chemoprotectors of bone marrow. Bone Marrow Transplant. 12:551.
36. Neta, R., R. Perlstein, S. N. Vogel, G. D. Ledney, and J. Abrams. 1992. Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor. J. Exp. Med. 175:689.
37. Zsebo, K. M., K. A. Smith, C. A. Hartley, M. Greenblatt, K. Cooke, W. Rich, and I. K. McNiece. 1992. Radioprotection of mice by recombinant rat stem cell factor. Proc. Nat. Acad. Sci. USA 89:9464.
38. Neta, R., S. M. Stiefel, F. Finkelman, S. Herrmann, and N. Ali. 1994. IL-12 protects bone marrow from and sensitizes intestinal tract to ionizing radiation. J. Immunol. 153:4230.
39. Wong, G. H. 1995. Protective roles of cytokines against radiation: induction of mitochondrial MmSOD. Biochim. Biophys. Acta 1271:205.
40. Hahn, S. M., C. M. Krishna, A. Samuni, W. DeGraff, D. O. Cuscela, P. Johnstone, and J. B. Mitchell. 1994. Potential use of nitroxides in radiation oncology. Cancer Res. 54:2006s.
41. Sorenson, J. R., L. S. Soderberg, and L. W. Chang. 1995. Radiation protection and radiation recovery with essential metalloelement chelates. Proc. Soc. Exp. Biol. Med. 210:191.
42. Maze, R., T. Moritz, and D. A. Williams. 1994. Increased survival and multilineage hematopoietic protection from delayed and severe myelosuppressive effects of a nitrosurea with recombinant interleukin-11. Cancer Res. 54:4947.
43. Rubin, P., C. J. Johnston, J. P. Williams, S. McDonald, and J. N. Finkelstein. 1995. A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 33:99.
44. McBride, W. H. 1995. Cytokine cascades in late normal tissue radiation responses. Int. J. Radiat. Oncol. Biol. Phys. 33:233.
45. Fuks, Z., and M. D. Weichselbaum. 1992. Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung. Int. J. Radiat. Oncol. Biol. Phys. 24:183.
46. Finkelstein, J. N., C. J. Johnston, R. Baggs, and P. Rubin. 1993. Early alterations in extracellular matrix and transforming growth factor β gene expression in mouse lung indicative of late radiation fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 28:621.
47. O'Brien-Ladner, A., M. E. Nelson, B. F. Kimler, and L. J. Wesselius. 1993. Release of interleukin-1 by human alveolar macrophages after in vitro irradiation. Radiat. Res. 136:37.
48. Langberg, C. W., M. Hauer-Hensen, C. C. Sung, and C. J. M. Kane. 1994. Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiother. Oncol. 32:29.
49. Piquet, P. F., M. A. Collart, G. E. Grau, A. P. Sappino, and P. Vassalli. 1990. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344:245.
50. Piquet, P. F., M. A. Colart, G. E. Grau, Y. Kapanci, and P. Vassalli. 1989. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J. Exp. Med. 170:655.
51. Piquet, P. F., and C. Vesin. 1994. Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. Eur. Respir. J. 7:515.
52. Peterson, R. L., W. L. Trepicchio, M. M. Bozza, L. Wang, and A. J. Dorner. 1995. G1 growth arrest and reduced proliferation of intestinal epithelial cells induced by rhIL-11 may mediate protection against mucositis. Blood 86:311A.
53. Trepicchio, W. L., M. Bozza, and A. J. Dorner. 1995. Recombinant human interleukin-11 attenuates the inflammatory response through downregulation of proinflammatory cytokine production and nitric oxide release. Blood 86s:424a.
54. Chen, M., J. Quintans, Z. Fuks, C. Thompson, D. W. Kufe, and R. R. Weichselbaum. 1995. Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor α and ceramide. Cancer Res. 55:991.
55. Paul, S. R., and P. Schendel. 1992. The cloning and biological characterization of recombinant human interleukin-11. Int. J. Cell Cloning 10:135.
56. Schindler, R., J. Mancilla, S. Endres, R. Ghorbani, S. C. Clark, and C. A. Dinarello. 1990. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 75:40.