메뉴 건너뛰기




Volumn 105, Issue 4, 2003, Pages 513-518

Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole

Author keywords

Bradykinin; Cytochrome P450; Endothelium derived hyperpolarizing factor; Forearm; Sulphaphenazole; Vasodilatation

Indexed keywords

BRADYKININ; CYTOCHROME P450 2C9; IBUPROFEN; JENAPROFEN; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLACEBO; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE; SULFAPHENAZOLE;

EID: 0141888501     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20030118     Document Type: Article
Times cited : (36)

References (25)
  • 1
    • 0029885126 scopus 로고    scopus 로고
    • Endothelial dysfunction in atherosclerosis
    • Busse, R. and Fleming, I. (1996) Endothelial dysfunction in atherosclerosis. J. Vasc. Res. 33, 181-194
    • (1996) J. Vasc. Res. , vol.33 , pp. 181-194
    • Busse, R.1    Fleming, I.2
  • 2
    • 0034478694 scopus 로고    scopus 로고
    • Cytochrome P450 2C is an EDHF synthase in coronary arteries
    • Fleming, I. (2000) Cytochrome P450 2C is an EDHF synthase in coronary arteries. Trends Cardiovasc. Med. 10, 166-170
    • (2000) Trends Cardiovasc. Med. , vol.10 , pp. 166-170
    • Fleming, I.1
  • 3
    • 0034885499 scopus 로고    scopus 로고
    • Endothelium-derived relaxing factors: A focus on endothelium-derived hyperpolarizing factor(s)
    • McGuire, J. J., Ding, H. and Triggle, C. R. (2001) Endothelium-derived relaxing factors: a focus on endothelium-derived hyperpolarizing factor(s). Can. J. Physiol Pharmacol. 79, 443-470
    • (2001) Can. J. Physiol Pharmacol. , vol.79 , pp. 443-470
    • McGuire, J.J.1    Ding, H.2    Triggle, C.R.3
  • 5
    • 0033069799 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor(s): Species and tissue heterogeneity
    • Triggle, C. R., Dong, H., Waldron, G. J. and Cole, W. C. (1999) Endothelium-derived hyperpolarizing factor(s): species and tissue heterogeneity. Clin. Exp. Pharmacol. Physiol. 26, 176-179
    • (1999) Clin. Exp. Pharmacol. Physiol. , vol.26 , pp. 176-179
    • Triggle, C.R.1    Dong, H.2    Waldron, G.J.3    Cole, W.C.4
  • 7
    • 0033619262 scopus 로고    scopus 로고
    • Cytochrome P450 2C is an EDHF synthase in coronary arteries
    • Fisslthaler, B., Popp, R., Kiss, L. et al. (1999) Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature (London) 401, 493-497
    • (1999) Nature (London) , vol.401 , pp. 493-497
    • Fisslthaler, B.1    Popp, R.2    Kiss, L.3
  • 8
    • 0033525767 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone
    • Campbell, W. B. and Harder, D. R. (1999) Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone. Circ. Res. 84, 484-488
    • (1999) Circ. Res. , vol.84 , pp. 484-488
    • Campbell, W.B.1    Harder, D.R.2
  • 10
    • 0030456054 scopus 로고    scopus 로고
    • Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: Molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9
    • Mancy, A., Dijols, S., Poli, S., Guengerich, P. and Mansuy, D. (1996) Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9. Biochemistry 35, 16205-16212
    • (1996) Biochemistry , vol.35 , pp. 16205-16212
    • Mancy, A.1    Dijols, S.2    Poli, S.3    Guengerich, P.4    Mansuy, D.5
  • 11
    • 0034013033 scopus 로고    scopus 로고
    • Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450
    • Sai, Y., Dai, R., Yang, T. J. et al. (2000) Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450. Xenobiotica 30, 327-343
    • (2000) Xenobiotica , vol.30 , pp. 327-343
    • Sai, Y.1    Dai, R.2    Yang, T.J.3
  • 12
    • 0033870439 scopus 로고    scopus 로고
    • Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries
    • Fisslthaler, B., Hinsch, N., Chataigneau, T. et al. (2000) Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries. Hypertension 36, 270-275
    • (2000) Hypertension , vol.36 , pp. 270-275
    • Fisslthaler, B.1    Hinsch, N.2    Chataigneau, T.3
  • 13
    • 0029030732 scopus 로고
    • Measuring forearm blood flow and interpreting the responses to drugs and mediators
    • Benjamin, N., Calver, A., Collier, J., Robinson, B., Vallance, P. and Webb, D. (1995) Measuring forearm blood flow and interpreting the responses to drugs and mediators. Hypertension 25, 918-923
    • (1995) Hypertension , vol.25 , pp. 918-923
    • Benjamin, N.1    Calver, A.2    Collier, J.3    Robinson, B.4    Vallance, P.5    Webb, D.6
  • 14
    • 0021019421 scopus 로고
    • Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm
    • Carlsson, I. and Wennmalm, A. (1983) Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. Prostaglandins 26, 241-252
    • (1983) Prostaglandins , vol.26 , pp. 241-252
    • Carlsson, I.1    Wennmalm, A.2
  • 15
    • 0035159168 scopus 로고    scopus 로고
    • G-monomethyl-L-arginine of responses to endothelium-dependent vasodilators in human forearm vasculature
    • G-monomethyl-L-arginine of responses to endothelium-dependent vasodilators in human forearm vasculature. Br. J. Pharmacol. 134, 939-944
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 939-944
    • Dawes, M.1    Chowienczyk, P.J.2    Ritter, J.M.3
  • 17
    • 0037239745 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans
    • Cambridge, U.K.
    • Hillig, T., Krustrup, P., Fleming, I., Osada, T., Saltin, B. and Hellsten, Y. (2003) Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans. J. Physiol. (Cambridge, U.K.) 546, 307-314
    • (2003) J. Physiol. , vol.546 , pp. 307-314
    • Hillig, T.1    Krustrup, P.2    Fleming, I.3    Osada, T.4    Saltin, B.5    Hellsten, Y.6
  • 18
    • 0034119983 scopus 로고    scopus 로고
    • Bradykinin-induced vasodilation of human forearm resistance vessels is primarily mediated by endothelium-dependent hyperpolarization
    • Honing, M. L., Smits, P., Morrison, P. J. and Rabelink, T. J. (2000) Bradykinin-induced vasodilation of human forearm resistance vessels is primarily mediated by endothelium-dependent hyperpolarization. Hypertension 35, 1314-1318
    • (2000) Hypertension , vol.35 , pp. 1314-1318
    • Honing, M.L.1    Smits, P.2    Morrison, P.J.3    Rabelink, T.J.4
  • 21
    • 0030469546 scopus 로고    scopus 로고
    • Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor
    • Bauersachs, J., Popp, R., Hecker, M., Sauer, E., Fleming, I. and Busse, R. (1996) Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation 94, 3341-3347
    • (1996) Circulation , vol.94 , pp. 3341-3347
    • Bauersachs, J.1    Popp, R.2    Hecker, M.3    Sauer, E.4    Fleming, I.5    Busse, R.6
  • 22
    • 0033613094 scopus 로고    scopus 로고
    • Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients
    • Taddei, S., Ghiadoni, L., Virdis, A., Buralli, S. and Salvetti, A. (1999) Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients. Circulation 100, 1400-1405
    • (1999) Circulation , vol.100 , pp. 1400-1405
    • Taddei, S.1    Ghiadoni, L.2    Virdis, A.3    Buralli, S.4    Salvetti, A.5
  • 23
    • 0035570723 scopus 로고    scopus 로고
    • Age-related reduction of NO availability and oxidative stress in humans
    • Taddei, S., Virdis, A., Ghiadoni, L. et al. (2001) Age-related reduction of NO availability and oxidative stress in humans. Hypertension 38, 274-279
    • (2001) Hypertension , vol.38 , pp. 274-279
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3
  • 25
    • 0035910620 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor synthase (cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries
    • Fleming, I., Michaelis, U. R., Bredenkotter, D. et al. (2001) Endothelium-derived hyperpolarizing factor synthase (cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ. Res. 88, 44-51
    • (2001) Circ. Res. , vol.88 , pp. 44-51
    • Fleming, I.1    Michaelis, U.R.2    Bredenkotter, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.