The effect of cell culture conditions on saquinavir transport through, and interactions with, MDCKII cells overexpressing hMDR1

Journal of Pharmaceutical Sciences

Volumn 92, Issue 10, 2003, Pages 1957-1967

  Williams, Gregory C ^a   Knipp, Gregory T ^a   Sinko, Patrick J ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Cell culture; Collagen; Efflux pumps; Expression; MDCK cells; P glycoprotein; Saquinavir; Seeding density; Substratum; Transport

Indexed keywords

MANNITOL; POLYCARBONATE; SAQUINAVIR;

ACTIVE TRANSPORT; ANIMAL CELL; ARTICLE; CELL CULTURE; DRUG PENETRATION; DRUG TRANSPORT; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; MONOLAYER CULTURE; NONHUMAN; PGP GENE;

EID: 0141819197     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10458     Document Type: Article

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