Cyclical mechanical stretch-induced apoptosis in myocytes from young rats but necrosis in myocytes from old rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 4 54-4, 2003, Pages

  Husse, B ^a   Sopart, A ^a   Isenberg, G ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Age; Ventricular myocytes

Indexed keywords

DNA FRAGMENT; LACTATE DEHYDROGENASE; PROTEIN BCL 2; PROTEIN P53;

AGED; AGING; ANIMAL CELL; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; HEART MUSCLE CELL; HEART VENTRICLE; HEART WEIGHT; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

AGING; ANIMALS; APOPTOSIS; CELLS, CULTURED; CYTOCHROME C GROUP; HEART VENTRICLES; MYOCYTES, CARDIAC; NECROSIS; PERIODICITY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; STRESS, MECHANICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0141788732     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Anversa P and Kajstura J. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res 83: 1-14, 1998.
2. Banes A, Link G, Gilbert J, Tran Son Tay R, and Monbureau O. Culturing cells in a mechanically active environment. Am Biotechnol Lab 8: 12-22, 1990.
3. Bernardi P, Scorrano L, Colonna R, Petronilli V, and Di Lisa F. Mitochondria and cell death. Eur J Biochem 264: 687-701, 1999.
4. Centurione L, Antonucci A, Miscia S, Grilli A, Rapino M, Grifone G, Di Giacomo V, Di Giulio C, Falconi M, and Cataldi A. Age-related death-survival balance in myocardium: an immunohistochemical and biochemical study. Mech Ageing Dev 123: 341-350, 2002.
5. Cheng W, Kajstura J, Nitahara JA, Li B, Reiss K, Liu Y, Clark WA, Krajewski S, Reed JC, Olvetti G, and Anversa P. Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res 226: 316-327, 1996.
6. Cheng W, Li B, Kajstura J, Li P, Wolin MS, Sonnenblick EH, Hintze TH, Olivetti G, and Anversa P. Stretch-induced programmed myocyte cell death. J Clin Invest 96: 2247-2259, 1995.
7. Cox MJ, Sood HS, Hunt MJ, Chandler D, Henegar JR, Aru GM, and Tyagi SC. Apoptosis in the left ventricle of chronic volume overload causes endocardial endothelial dysfunction in rats. Am J Physiol Heart Circ Physiol 282: H1197-H1205, 2002.
8. De Moissac D, Gurevich RM, Zheng H, Singal PK, and Kirshenbaum LA. Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol 32: 53-63, 2000.
9. Desagher S and Martinou JC. Mitochondria as the central control point of apoptosis. Trends Cell Biol 10: 369-377, 2000.
10. Fiodaliso F, Leri A, Cesselli D, Limana F, Safai B, Nadal-Ginard B, Anversa P, and Kajstura J. Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death. Diabetes 50: 2363-2375, 2001.
11. Gill C, Mestril R, and Samali A. Losing heart: the role of apoptosis in heart disease-a novel therapeutic target? FASEB J 16: 135-146, 2002.
12. Guerra S, Leri A, Wang X, Finato N, Di Loreto C, Beltrami CA, Kajstura J, and Anversa P. Myocyte death in the failing human heart is gender dependent. Circ Res 85: 856-866, 1999.
13. Hagen TM, Moreau R, Suh JH, and Visioli F. Mitochondria decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. Ann NY Acad Sci 959: 491-507, 2002.
14. Halestrap AP, Doran E, Gillespie JP, and O'Toole A. Mitochondria and cell death. Biochem Soc Trans 28: 170-177, 2000.
15. Harper M, Monemdjou S, Ramsey JJ, and Weindruch R. Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes. Am J Physiol Endocrinol Metab 275: E197-E206, 1998.
16. Heinke MY, Yao M, Chang D, Einstein R, dos Remedios CG. Apoptosis of ventricular and atrial myocytes from pacing-induced canine heart failure. Cardiovasc Res 49: 127-134, 2001.
17. Hengartner MO. The biochemistry of apoptosis. Nature 407: 770-776, 2000.
18. Isenberg G and Klöckner U. Calcium tolerant ventricular myocytes prepared in a KB medium. Pflügers Arch 395: 5-18, 1982.
19. Isoyama S, Grossman W, and Wei JY. Effect of age on myocardial adaptation to volume overload in the rat. J Clin Invest 81: 1850-1857, 1988.
20. Kajstura J, Cheng W, Sarangarajan R, Li P, Li B, Nitahara JA, Chapnick S, Reiss K, Olivetti G, and Anversa P. Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol Heart Circ Physiol 271: H1215-H1228, 1996.
21. Kang PM and Izumo S. Apoptosis and heart failure. Circ Res 86: 1107-1113, 2000.
22. Kim SO, Katz S, and Pelech SL. Expression of second messengerand-cyclin-dependent protein kinases during postnatal development of rat heart. J Cell Biochem 69: 506-521, 1998.
23. Lee J, Yu BP, and Herlihy JT. Modulation of cardiac mitochondrial membrane fluidity by age and calorie intake. Free Radic Biol Med 26: 260-265, 1999.
24. Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, and Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 101: 1326-1342, 1998.
25. Leri A, Liu Y, Claudio PP, Kajstura J, Wang X, Wang S, Kang P, Malhotra A, and Anversa P. Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis. Am J Pathol 154: 567-580, 1999.
26. Nitahara JA, Cheng W, Liu Y, Li B, Leri A, Li P, Mogul D, Gambert SR, Kajstura J, and Anvesa P. Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats. J Mol Cell Cardiol 30: 519-535, 1998.
27. Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, Quanini E, Loreto CD, Beltrami CA, Krajewski S, Reed JC, and Anversa P. Apoptosis in the failing human heart. N Engl J Med 336: 1131-1141, 1997.
28. 2+ signaling and cardiac apoptosis. Biol Signals Recept 10: 200-223, 2000.
29. Pankuweit S, Jobmann M, Crombach M, Portig I, Alter P, Kruse T, Hufnagel G, and Maisch B. Myocyte destruction in inflammatory cardiomyopathy-apoptosis or necrosis? Herz 24: 211-218, 1999.
30. Phaneuf S and Leeuwenburgh C. Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age. Am J Physiol Regul Integr Comp Physiol 282: R423-R430, 2002.
31. Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-Krasinski J, Baliga R, Wang J, Siwik DA, Singh K, Pagano P, Colucci WS, and Sawyer DB. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ Res 89: 453-460, 2001.
32. Pollack M, Phaneuf S, Dirks A, and Leeuwenburgh C. The role of apoptosis in the normal aging brain, skeletal muscle, and heart. Ann NY Acad Sci 959: 93-107, 2002.
33. Rayment NB, Haven AJ, Madden B, Murday A, Trickey R, Shipley M, Davies MJ, and Katz DR. Myocyte loss in chronic heart failure. J Pathol 188: 213-219, 1999.
34. Reed JC. Apoptosis-regulating proteins as targets for drug discovery. Trends Mol Med 7: 314-319, 2001.
35. Saraste A. Morphologic criteria and detection of apoptosis. Herz 24: 189-195, 1999.
36. Scheubel RJ, Bartling B, Simm A, Silber RE, Drogaris K, Darmer D, and Holtz J. Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium. J Am Coll Cardiol 39: 481-488, 2002.
37. Sparagna GC, Hickson-Bick DL, Buja LM, and McMillin JB. A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis. Am J Physiol Heart Circ Physiol 279: H2124-H2132, 2000.
38. Suzuki K, Kostin S, Person V, Elsässer A, and Schaper J. Time course of the apoptotic cascade and effects of caspase inhibitors in adult rat ventricular cardiomyocytes. J Mol Cell Cardiol 33: 983-994, 2001.
39. Takahashi T, Schunkert H, Isoyama S, Wei JY, Nadal-Ginard B, Grossman W, and Izumo S. Age related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium. J Clin Invest 89: 939-946, 1992.
40. Tate CA, Helgason T, Hyedk MF, Mcbride RP, Chen M, Richardson MA, and Taffet GE. SERCA2a and mitochondrial cytochrome oxidase expression are increased in hearts of exercise-trained old rats. Am J Physiol Heart Circ Physiol 271: H68-H72, 1996.
41. Teiger E, Dam TY, Richard L, Wisnewsky C, Tea BS, Gaboury L, Tremblay J, Schwartz K, and Hamet P. Apoptosis in pressure overload-induced heart hypertrophy in the rat. J Clin Invest 97: 2891-2897, 1996.
42. Xiao R, Spurgeon HA, O'Connor F, and Lakatta EG. Age-associated changes in β-adrenergic modulation on rat cardiac excitation-contraction coupling, J Clin Invest 94: 2051-2059, 1994.