Enantiospecific formal total synthesis of the tumor and GSK-3β inhibiting alkaloid, (-)-agelastatin A

Organic Letters

Volumn 5, Issue 16, 2003, Pages 2927-2930

  Hale, Karl J ^a   Domostoj, Mathias M ^a   Tocher, Derek A ^a   Irving, Ed ^b   Scheinmann, Feodor ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Medicinal Chemistry Department   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGELASTATIN A; ALKALOID DERIVATIVE; AZIDE; GLYCOGEN SYNTHASE KINASE 3BETA; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CIRCULAR DICHROISM; CYCLOADDITION; DIELS ALDER REACTION; DRUG INHIBITION; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RING CLOSING METATHESIS; RING OPENING; STEREOCHEMISTRY;

ALKALOIDS; ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; OXAZOLIDINONES; STEREOISOMERISM;

EID: 0141743548     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035036l     Document Type: Article

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