Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice

Physiological Genomics

Volumn 13, Issue , 2003, Pages 47-56

  Weide, Karin ^a   Christ, Nicole ^a   Moar, Kim M ^b   Arens, Janine ^c   Hinney, Anke ^d   Mercer, Julian G ^b   Eiden, Sandra ^a   Schmidt, Ingrid ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Energy expenditure; Genetic obesity; Neuropeptide Y; Pro opiomelanocortin

Indexed keywords

LEPTIN; MELANOCORTIN 4 RECEPTOR; MESSENGER RNA; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; CORTICOTROPIN RECEPTOR; NEUROPEPTIDE Y C-TERMINAL FLANKING PEPTIDE; NEUROPEPTIDE Y CARBOXY TERMINAL FLANKING PEPTIDE; PEPTIDE FRAGMENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; ENERGY EXPENDITURE; FEMALE; FOOD INTAKE; GENE MUTATION; HORMONE BLOOD LEVEL; HUMAN; HYPERMETABOLISM; HYPERPHAGIA; KNOCKOUT MOUSE; LIPID STORAGE; MALE; METABOLIC DISORDER; MOUSE; NEWBORN; NONHUMAN; OBESITY; ONSET AGE; PRIORITY JOURNAL; WEANING; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; BLOOD; CALORIC INTAKE; EATING; ENERGY METABOLISM; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALIA;

ADIPOSE TISSUE; ANIMALS; BODY COMPOSITION; EATING; ENERGY INTAKE; ENERGY METABOLISM; FEMALE; GENOTYPE; HYPERPHAGIA; LEPTIN; MALE; MICE; MICE, KNOCKOUT; NEUROPEPTIDE Y; OBESITY; PEPTIDE FRAGMENTS; PRO-OPIOMELANOCORTIN; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, CORTICOTROPIN;

EID: 0141703205     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00129.2002     Document Type: Article

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