메뉴 건너뛰기




Volumn 134, Issue 1, 2003, Pages 98-106

Reconstitution of CD4+ T cell responses in HIV-1 infected individuals initiating highly active antiretroviral therapy (HAART) is associated with renewed interleukin-2 production and responsiveness

Author keywords

Highly active antiretroviral therapy (HAART); Interleukin 2; Interleukin 4; Lymphocyte proliferation; T cell anergy

Indexed keywords

ANTIRETROVIRUS AGENT; INTERLEUKIN 2; INTERLEUKIN 4;

EID: 0141650594     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2003.02256.x     Document Type: Article
Times cited : (34)

References (39)
  • 1
    • 0023789637 scopus 로고
    • Impaired T lymphocyte dependent immune responses to microbial antigens in patients with HIV-1 associated persistent generalised lymphadenopathy
    • Ballett JJ, Couderc L-J, Rabian-Herzog C et al. Impaired T lymphocyte dependent immune responses to microbial antigens in patients with HIV-1 associated persistent generalised lymphadenopathy. AIDS 1988; 2:291-7.
    • (1988) AIDS , vol.2 , pp. 291-297
    • Ballett, J.J.1    Couderc, L.-J.2    Rabian-Herzog, C.3
  • 4
    • 0025160079 scopus 로고
    • + memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T cell functional defects observed in infected individuals
    • + memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T cell functional defects observed in infected individuals. Proc Natl Acad Sci 1990; 87:6058-62.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 6058-6062
    • Schnittman, S.M.1    Lane, C.H.2    Greenhouse, J.3    Justement, J.S.4    Baseler, M.5    Fauci, A.S.6
  • 5
    • 0032941595 scopus 로고    scopus 로고
    • +T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
    • +T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. Nat Med 1999; 5:483-4.
    • (1999) Nat Med , vol.5 , pp. 483-484
    • Pitcher, C.J.1    Quittner, C.2    Peterson, D.M.3
  • 6
    • 0033823570 scopus 로고    scopus 로고
    • + T cell proliferative ability but not loss of human immunodeficiency virus type 1 specificity equates with progression to disease
    • + T cell proliferative ability but not loss of human immunodeficiency virus type 1 specifcity equates with progression to disease. J Infect Dis 2000; 182:792-8.
    • (2000) J Infect Dis , vol.182 , pp. 792-798
    • Wilson, J.D.1    Imami, N.2    Watkins, A.3
  • 7
    • 0027409391 scopus 로고
    • T cell dysfunction in HIV infection: Anergy due to defective antigen-presenting cell function?
    • Meyaard L, Schuitemaker H, Miedema F. T cell dysfunction in HIV infection: anergy due to defective antigen-presenting cell function? Immunol Today 1993; 14:161-4.
    • (1993) Immunol Today , vol.14 , pp. 161-164
    • Meyaard, L.1    Schuitemaker, H.2    Miedema, F.3
  • 8
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 9
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnami S. The Th1/Th2 paradigm. Immunol Today 1997; 18:263-6.
    • (1997) Immunol Today , vol.18 , pp. 263-266
    • Romagnami, S.1
  • 10
    • 0027971622 scopus 로고
    • + cytotoxic T cell responses during chronic viral infections
    • + cytotoxic T cell responses during chronic viral infections. J Virol 1994; 68:8056-63.
    • (1994) J Virol , vol.68 , pp. 8056-8063
    • Matloubian, M.1    Concepcion, R.J.2    Ahmed, R.3
  • 12
    • 0141665016 scopus 로고
    • Kinetics of gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: A longitudinal analysis of rapid progressors and long term asymptomatics
    • Klein MR, van Baalen CA, Holwerda AM et al. Kinetics of gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long term asymptomatics. J Exp Med 1995; 8:903-7.
    • (1995) J Exp Med , vol.8 , pp. 903-907
    • Klein, M.R.1    Van Baalen, C.A.2    Holwerda, A.M.3
  • 13
    • 0028944192 scopus 로고
    • HIV-specific cytotoxic T cells in HIV-exposed but uninfected Gambian women
    • Rowland Jones SL, Sutton J, Ariyoshi K et al. HIV-specific cytotoxic T cells in HIV-exposed but uninfected Gambian women. Nat Med 1995; 1:59-64.
    • (1995) Nat Med , vol.1 , pp. 59-64
    • Rowland Jones, S.L.1    Sutton, J.2    Ariyoshi, K.3
  • 14
    • 0028866238 scopus 로고
    • + nef-specific cytotoxic T cells in vaccinated macaques
    • + nef-specific cytotoxic T cells in vaccinated macaques. Nat Med 1995; 11:1167-73.
    • (1995) Nat Med , vol.11 , pp. 1167-1173
    • Gallimore, A.1    Cranage, M.2    Cook, N.3
  • 15
    • 0029900651 scopus 로고    scopus 로고
    • + T cells in macaques protected from SIV challenge by prior SIV subunit vaccination
    • + T cells in macaques protected from SIV challenge by prior SIV subunit vaccination. J Virol 1996; 70:4941-7.
    • (1996) J Virol , vol.70 , pp. 4941-4947
    • Kent, S.1    Hu, S.-L.2    Corey, L.3    Morton, W.4    Greenburg, P.5
  • 16
    • 0035667633 scopus 로고    scopus 로고
    • Understanding cytotoxic T lymphocyte escape during simian immunodeficiency virus infection
    • O'Connor D, Friedrich T, Hughes A, Allen TM, Watkins D. Understanding cytotoxic T lymphocyte escape during simian immunodeficiency virus infection. Immunol Rev 2001; 183:115-26.
    • (2001) Immunol Rev , vol.183 , pp. 115-126
    • O'Connor, D.1    Friedrich, T.2    Hughes, A.3    Allen, T.M.4    Watkins, D.5
  • 17
    • 0036113306 scopus 로고    scopus 로고
    • Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection
    • O'Connor DH, Allen TM, Vogel TU et al. Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nat Med 2002; 8:493-9.
    • (2002) Nat Med , vol.8 , pp. 493-499
    • O'Connor, D.H.1    Allen, T.M.2    Vogel, T.U.3
  • 18
    • 0027340164 scopus 로고
    • A Th1 to Th2 switch is a critical step in the etiology of HIV infection
    • Clerici M, Shearer GM. A Th1 to Th2 switch is a critical step in the etiology of HIV infection. Immunol Today 1993; 14:107-10.
    • (1993) Immunol Today , vol.14 , pp. 107-110
    • Clerici, M.1    Shearer, G.M.2
  • 19
    • 0035282444 scopus 로고    scopus 로고
    • Skewed maturation of memory HIV-specific CD8 T lymphocytes
    • Champagne P, Ogg GS, King AS et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001; 410:106-11.
    • (2001) Nature , vol.410 , pp. 106-111
    • Champagne, P.1    Ogg, G.S.2    King, A.S.3
  • 20
    • 0027403718 scopus 로고
    • Quantitative analysis of the human immunodeficiency virus type-1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different disease stages of HIV-1 infection: Differential CTL responses to HIV-1 and Epstein-Barr virus in late disease
    • Carmichael A, Jin X, Sissons P, Borysiewicz L. Quantitative analysis of the human immunodeficiency virus type-1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different disease stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease. J Exp Med 1993; 177:249.
    • (1993) J Exp Med , vol.177 , pp. 249
    • Carmichael, A.1    Jin, X.2    Sissons, P.3    Borysiewicz, L.4
  • 21
    • 0032885310 scopus 로고    scopus 로고
    • Therapeutic vaccines in HIV-1 infection
    • Gotch F, Hardy G, Imami N. Therapeutic vaccines in HIV-1 infection. Immunol Rev 1999; 170:173-82.
    • (1999) Immunol Rev , vol.170 , pp. 173-182
    • Gotch, F.1    Hardy, G.2    Imami, N.3
  • 22
    • 0032089101 scopus 로고    scopus 로고
    • HIV type-1 specific helper-T cells: A critical host defence
    • Rosenberg ES, Walker BD. HIV type-1 specific helper-T cells: a critical host defence. AIDS Res Hum Ret 1998; 14:S143-7.
    • (1998) AIDS Res Hum Ret , vol.14
    • Rosenberg, E.S.1    Walker, B.D.2
  • 24
    • 0032552471 scopus 로고    scopus 로고
    • Long-term non progression in HIV infection. Methodological issues and scientific priorities. Workshop summary
    • Easterbrook PJ, Schrager LK. Long-term non progression in HIV infection. Methodological issues and scientific priorities. Workshop summary. AIDS Res Hum Ret 1998; 14:1211-28.
    • (1998) AIDS Res Hum Ret , vol.14 , pp. 1211-1228
    • Easterbrook, P.J.1    Schrager, L.K.2
  • 25
    • 0030952479 scopus 로고    scopus 로고
    • Decay characteristics of HIV-1-infected compartments during combination therapy
    • Perelson AS, Essunger P, Cao Y et al. Decay characteristics of HIV-1-infected compartments during combination therapy. Nature 1997; 387:188-91.
    • (1997) Nature , vol.387 , pp. 188-191
    • Perelson, A.S.1    Essunger, P.2    Cao, Y.3
  • 26
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • Palella FJ, Delaney KM, Moorman AC et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998; 338:853-60.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 27
    • 0030052964 scopus 로고    scopus 로고
    • Alterations in the immune response of HIV infected subjects treated with an HIV-specific protease inhibitor, Ritonavir
    • Kelleher AD, Carr A, Zaunders J, Cooper DA. Alterations in the immune response of HIV infected subjects treated with an HIV-specific protease inhibitor, Ritonavir. J Infect Dis 1996; 9:321-9.
    • (1996) J Infect Dis , vol.9 , pp. 321-329
    • Kelleher, A.D.1    Carr, A.2    Zaunders, J.3    Cooper, D.A.4
  • 28
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV infection: A composite of redistribution and proliferation
    • Pakker NG, Notermans DW, de Boer RJ et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV infection: a composite of redistribution and proliferation. Nature Med 1998; 4:208-14.
    • (1998) Nature Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    De Boer, R.J.3
  • 29
    • 0032490305 scopus 로고    scopus 로고
    • Long lasting recovery in CD4 cell function and viral load reduction after highly active antiretroviral therapy in advance HIV-1 disease
    • Li TS, Tubiana R, Katlama C et al. Long lasting recovery in CD4 cell function and viral load reduction after highly active antiretroviral therapy in advance HIV-1 disease. Lancet 1998; 351:1682-6.
    • (1998) Lancet , vol.351 , pp. 1682-1686
    • Li, T.S.1    Tubiana, R.2    Katlama, C.3
  • 30
    • 0033051593 scopus 로고    scopus 로고
    • Functional T cell reconstitution and human immunodeficiency virus-1-specific cell mediated immunity during highly active antiretroviral therapy
    • Pontesilli O, Kerhof-Garde S, Notermans DW et al. Functional T cell reconstitution and human immunodeficiency virus-1-specific cell mediated immunity during highly active antiretroviral therapy. J Infect Dis 1999; 180:76-86.
    • (1999) J Infect Dis , vol.180 , pp. 76-86
    • Pontesilli, O.1    Kerhof-Garde, S.2    Notermans, D.W.3
  • 31
  • 32
    • 0032859377 scopus 로고    scopus 로고
    • Induction of HIV-1-specific T cell responses by administration of cytokines in late-stage patients receiving highly active antiretroviral therapy
    • Imami N, Hardy GAD, Nelson MR. Induction of HIV-1-specific T cell responses by administration of cytokines in late-stage patients receiving highly active antiretroviral therapy. Clin Exp Immunol 1999; 118:78-86.
    • (1999) Clin Exp Immunol , vol.118 , pp. 78-86
    • Imami, N.1    Hardy, G.A.D.2    Nelson, M.R.3
  • 33
    • 0036720427 scopus 로고    scopus 로고
    • A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infection
    • Imami N, Pires A, Hardy G, Wilson J, Gazzard B, Gotch F. A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infection. J Virol 2002; 76:9011-23.
    • (2002) J Virol , vol.76 , pp. 9011-9023
    • Imami, N.1    Pires, A.2    Hardy, G.3    Wilson, J.4    Gazzard, B.5    Gotch, F.6
  • 34
    • 16944367032 scopus 로고    scopus 로고
    • + T cell repertoire that are not immediately restored by antiviral or immune-based therapies
    • + T cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nat Med 1997; 3:533-40.
    • (1997) Nat Med , vol.3 , pp. 533-540
    • Connors, M.1    Kovacs, J.A.2    Krevat, S.3
  • 35
    • 0033589663 scopus 로고    scopus 로고
    • Assessment of type 1 and type 2 cytokines in HIV type 1-infected individuals: Impact of highly active antiretroviral therapy
    • Imami N, Antonopoulos C, Hardy GAD, Gazzard B, Gotch FM. Assessment of type 1 and type 2 cytokines in HIV type 1-infected individuals: Impact of highly active antiretroviral therapy. AIDS Res Hum Ret 1999; 15:1499-508.
    • (1999) AIDS Res Hum Ret , vol.15 , pp. 1499-1508
    • Imami, N.1    Antonopoulos, C.2    Hardy, G.A.D.3    Gazzard, B.4    Gotch, F.M.5
  • 38
    • 0027281563 scopus 로고
    • The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory
    • Akbar AN, Borthwick N, Salmon M et al. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J Exp Med 1993; 178:427-38.
    • (1993) J Exp Med , vol.178 , pp. 427-438
    • Akbar, A.N.1    Borthwick, N.2    Salmon, M.3
  • 39
    • 0028063403 scopus 로고
    • + T cells undergoing apoptosis: A mechanism for T cell clearance during resolution of viral infections
    • + T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections. J Exp Med 1994; 180:1943-7.
    • (1994) J Exp Med , vol.180 , pp. 1943-1947
    • Akbar, A.N.1    Savill, J.2    Gombert, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.