Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease

Journal of Medicinal Chemistry

Volumn 39, Issue 26, 1996, Pages 5072-5082

  Webber, Stephen E ^a   Tikhe, Jayashree ^a   Worland, Stephen T ^a   Fuhrman, Shella A ^a   Hendrickson, Thomas F ^a   Matthews, David A ^a   Love, Robert A ^a   Patick, Amy K ^a   Meador, James W ^a   Ferre, Rose Ann ^a   Brown, Edward L ^a   Delisle, Dorothy M ^a   Ford, Clifford E ^a   Binford, Susan L ^a  

^a AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 BENZO[B]THIOPHENYLMETHYL)ISATIN 5 CARBOXAMIDE; 1 METHYLISATIN 5 CARBOXAMIDE; CINNAMYLISATIN 5 CARBOXAMIDE; ISATIN DERIVATIVE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS ENZYME;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN RHINOVIRUS; NONHUMAN;

ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; THERMODYNAMICS; VIRAL PROTEINS;

EID: 12644306888     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960603e     Document Type: Article

References (54)

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