Canstatin inhibits Akt activation and induces Fas-dependent apoptosis in endothelial cells

Journal of Biological Chemistry

Volumn 278, Issue 39, 2003, Pages 37632-37636

  Panka, David J ^b   Mier, James W ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; BIOLOGICAL MEMBRANES; COLLAGEN;

APOPTOSIS;

ENZYME INHIBITION;

BINDING PROTEIN; CANSTATIN; CASPASE 8; CASPASE 9; COLLAGEN TYPE 4; ENZYME PRECURSOR; FAS ANTIBODY; FAS LIGAND; FLICE INHIBITORY PROTEIN; INITIATION FACTOR 4E; MEMBRANE RECEPTOR; NEUTRALIZING ANTIBODY; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIDIUM IODIDE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD95; APOPTOSIS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELLS, CULTURED; COLLAGEN TYPE IV; ENDOTHELIUM, VASCULAR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA;

EUKARYOTA; MAMMALIA;

EID: 0141621149     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307339200     Document Type: Article

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