-
1
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Nakayama K, Ishida N, Shirane M et al. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996;85:707-720.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
-
2
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
Kiyokawa H, Kineman RD, Manova-Todorova KO et al. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 1996;85:721-732.
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
-
3
-
-
0032511848
-
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
-
Fero ML, Randel E, Gurley KE, Roberts JM, Kemp CJ. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 1998;396:177-180.
-
(1998)
Nature
, vol.396
, pp. 177-180
-
-
Fero, M.L.1
Randel, E.2
Gurley, K.E.3
Roberts, J.M.4
Kemp, C.J.5
-
4
-
-
0030840987
-
Transforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip 1 expression in nontumorous and neoplastic human pituitaries
-
Jin L, Qian X, Kulig E et al. Transforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip 1 expression in nontumorous and neoplastic human pituitaries. Am J Pathol 1997;151:509-519.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 509-519
-
-
Jin, L.1
Qian, X.2
Kulig, E.3
-
5
-
-
0029894515
-
Transforming growth factor-beta and p27 expression in pituitary cells
-
Qian X, Jin L, Grande JP, Lloyd RV. Transforming growth factor-beta and p27 expression in pituitary cells. Endocrinology 1996-1137:3051-3060.
-
(1996)
Endocrinology
, vol.137
, pp. 3051-3060
-
-
Qian, X.1
Jin, L.2
Grande, J.P.3
Lloyd, R.V.4
-
6
-
-
0033304951
-
Low expression of the cell cycle inhibitor p27Kip 1 in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumors
-
Lidhar K, Korbonits M, Jordan S et al. Low expression of the cell cycle inhibitor p27Kip 1 in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumors. J Clin Endocrinol Metab 1999;84:3823-3830.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 3823-3830
-
-
Lidhar, K.1
Korbonits, M.2
Jordan, S.3
-
7
-
-
15144350828
-
Mutation and expression analysis of the p27/kip 1 gene in corticotrophin-secreting tumours
-
Dahia PL, Aguiar RC, Honegger J et al. Mutation and expression analysis of the p27/kip 1 gene in corticotrophin-secreting tumours. Oncogene 1998;16:69-76.
-
(1998)
Oncogene
, vol.16
, pp. 69-76
-
-
Dahia, P.L.1
Aguiar, R.C.2
Honegger, J.3
-
8
-
-
18444413232
-
kip1 protein and Jab 1 (Jun activation domain-binding protein 1) in human pituitary tumors
-
Kip1 protein and Jab1 (Jun activation domain-binding protein 1) in human pituitary tumors. J Clin Endocrinol Metab 2002;8:2635-2643.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.8
, pp. 2635-2643
-
-
Korbonits, M.1
Chahal, H.S.2
Kaltsas, G.3
-
9
-
-
0034296394
-
The ubiquitin system
-
Basic Medical Research Award
-
Hershko A, Ciechanover A, Varshavsky A. Basic Medical Research Award. The ubiquitin system. Nat Med 2000;6:1073-1081.
-
(2000)
Nat. Med.
, vol.6
, pp. 1073-1081
-
-
Hershko, A.1
Ciechanover, A.2
Varshavsky, A.3
-
10
-
-
0028980273
-
p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
-
Zhang H, Kobayashi R, Galaktionov K, Beach D. p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell 1995;82:915-925.
-
(1995)
Cell
, vol.82
, pp. 915-925
-
-
Zhang, H.1
Kobayashi, R.2
Galaktionov, K.3
Beach, D.4
-
11
-
-
0035340719
-
Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas
-
Hershko D, Bornstein G, Ben Izhak O et al. Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. Cancer 2001;91:1745-1751.
-
(2001)
Cancer
, vol.91
, pp. 1745-1751
-
-
Hershko, D.1
Bornstein, G.2
Ben Izhak, O.3
-
12
-
-
0034676443
-
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex
-
Schulman BA, Carrano AC, Jeffrey PD et al. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature 2000;408:381-386.
-
(2000)
Nature
, vol.408
, pp. 381-386
-
-
Schulman, B.A.1
Carrano, A.C.2
Jeffrey, P.D.3
-
13
-
-
0033174070
-
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells
-
Sutterluty H, Chatelain E, Marti A et al. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol 1999;1:207-214.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 207-214
-
-
Sutterluty, H.1
Chatelain, E.2
Marti, A.3
-
14
-
-
0029975624
-
Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)
-
Demetrick DJ, Zhang H, Beach DH. Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2). Cytogenet Cell Genet 1996;73:104-107.
-
(1996)
Cytogenet. Cell Genet.
, vol.73
, pp. 104-107
-
-
Demetrick, D.J.1
Zhang, H.2
Beach, D.H.3
-
17
-
-
0037372015
-
Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells
-
Lin R, Wang TT, Miller WH Jr, White JH. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells. Endocrinology 2003;144:749-753.
-
(2003)
Endocrinology
, vol.144
, pp. 749-753
-
-
Lin, R.1
Wang, T.T.2
Miller W.H., Jr.3
White, J.H.4
-
18
-
-
0035726429
-
The release of leptin and its effect on hormone release from human pituitary adenomas
-
Korbonits M, Chitnis MM, Norman D et al. The release of leptin and its effect on hormone release from human pituitary adenomas. Clin Endocrinol (Oxf) 2001;54:781-789.
-
(2001)
Clin. Endocrinol. (Oxf)
, vol.54
, pp. 781-789
-
-
Korbonits, M.1
Chitnis, M.M.2
Norman, D.3
-
20
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda M, Cukor B, Tam SW et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-234.
-
(1997)
Nat. Med.
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
-
21
-
-
16944363001
-
Decreased levels of the cell cycle inhibitor p27/kip1 protein: Prognostic implications in primary breast cancer
-
Catzavelos C, Bhattacharya N, Ung YC et al. Decreased levels of the cell cycle inhibitor p27/kip1 protein: Prognostic implications in primary breast cancer. Nat Med 1997;3:227-230.
-
(1997)
Nat. Med.
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
-
22
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1999;1:193-199.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
23
-
-
0033130137
-
Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
-
Marti A, Wirbelauer C, Scheffner M, Krek W, Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation. Nat Cell Biol 1999;1:14-19.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 14-19
-
-
Marti, A.1
Wirbelauer, C.2
Scheffner, M.3
Krek, W.4
-
24
-
-
0034595292
-
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
-
Nakayama K, Nagahama H, Minamishima YA et al. Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication. EMBO J 2000;19:2069-2081.
-
(2000)
EMBO J.
, vol.19
, pp. 2069-2081
-
-
Nakayama, K.1
Nagahama, H.2
Minamishima, Y.A.3
-
25
-
-
0036733716
-
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
-
Signoretti S, Di Marcotullio L, Richardson A et al. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest 2002;110:633-641.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 633-641
-
-
Signoretti, S.1
Di Marcotullio, L.2
Richardson, A.3
-
26
-
-
0036847690
-
Elevated Skp2 protein expression in human prostate cancer: Association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival
-
Yang G, Ayala G, Marzo AD et al. Elevated Skp2 protein expression in human prostate cancer: Association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. Clin Cancer Res 2002;8:3419-3426.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3419-3426
-
-
Yang, G.1
Ayala, G.2
Marzo, A.D.3
-
27
-
-
0036861277
-
Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation
-
Penin RM, Fernandez-Figueras MT, Puig L, Rex J, Ferrandiz C, Ariza A. Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation. Mod Pathol 2002; 15:1227-1235.
-
(2002)
Mod. Pathol.
, vol.15
, pp. 1227-1235
-
-
Penin, R.M.1
Fernandez-Figueras, M.T.2
Puig, L.3
Rex, J.4
Ferrandiz, C.5
Ariza, A.6
-
28
-
-
0037108299
-
Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: Correlation with p27(Kip1) and proliferation index
-
Lim MS, Adamson A, Lin Z et al. Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: Correlation with p27(Kip1) and proliferation index. Blood 2002;100:2950-2956.
-
(2002)
Blood
, vol.100
, pp. 2950-2956
-
-
Lim, M.S.1
Adamson, A.2
Lin, Z.3
-
29
-
-
15644378138
-
Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells
-
Hirai A, Nakamura S, Noguchi Y et al. Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. J Biol Chem 1997;272:13-16.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13-16
-
-
Hirai, A.1
Nakamura, S.2
Noguchi, Y.3
-
30
-
-
0035921821
-
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase
-
Malek NP, Sundberg H, McGrew S et al. A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase. Nature 2001-1413:323-327.
-
(2001)
Nature
, vol.413
, pp. 323-327
-
-
Malek, N.P.1
Sundberg, H.2
McGrew, S.3
-
31
-
-
0035966104
-
Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway
-
Hara T, Kamura T, Nakayama K, Oshikawa K, Hatakeyama S, Nakayama K. Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway. J Biol Chem 2001;276:48937-48943.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48937-48943
-
-
Hara, T.1
Kamura, T.2
Nakayama, K.3
Oshikawa, K.4
Hatakeyama, S.5
Nakayama, K.6
|