Probing the Binding Pocket and Endocytosis of a G Protein-coupled Receptor in Live Cells Reported by a Spin-labeled Substance P Agonist

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 34203-34210

  Shafer, Aaron M ^a   Bennett, Vicki J ^b   Kim, Phillip ^c   Voss, John C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^c Peptidogenic Research and Co   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; LABELING; PARAMAGNETIC RESONANCE; PROTEINS;

ENDOCYTOSIS;

BIOCHEMISTRY;

G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATE; LYSINE; NEUROKININ 1 RECEPTOR; SUBSTANCE P DERIVATIVE; TACHYKININ RECEPTOR; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; LIGAND; MESSENGER RNA; PEPTIDE; PHOTOPROTEIN; SUBSTANCE P; TACHYKININ;

ANIMAL CELL; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; ELECTRON SPIN RESONANCE; ENDOCYTOSIS; ENDOSOME; HYDROLYSIS; INTERNALIZATION; LIGAND BINDING; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REPORTER GENE; SPIN LABELING; ANIMAL; CELL LINE; CHEMICAL MODEL; CHEMISTRY; CHO CELL; DOSE RESPONSE; DOWN REGULATION; GENE VECTOR; GENETIC TRANSFECTION; HAMSTER; METABOLISM; OOCYTE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RAT; TIME; XENOPUS;

ANIMALIA;

ANIMALS; BINDING SITES; CELL LINE; CHO CELLS; CRICETINAE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENDOCYTOSIS; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; GUANOSINE TRIPHOSPHATE; LIGANDS; LUMINESCENT PROTEINS; LYSINE; MODELS, CHEMICAL; OOCYTES; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RECEPTORS, NEUROKININ-1; RNA, MESSENGER; SPIN LABELS; SUBSTANCE P; TACHYKININS; TIME FACTORS; TRANSFECTION; XENOPUS;

EID: 0141594932     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212712200     Document Type: Article

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