An intron is required for dihydrofolate reductase protein stability

Journal of Biological Chemistry

Volumn 278, Issue 40, 2003, Pages 38292-38300

  Noé, Véronique ^a   MacKenzie, Simon ^b   Ciudad, Carlos J ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; ENZYMES; RNA; STABILITY;

INTRON-CONTAINING MINIGENES;

BIOCHEMISTRY;

DIHYDROFOLATE REDUCTASE; MESSENGER RNA; POLYADENYLATED RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; GENE EXPRESSION; GENETIC TRANSFECTION; HALF LIFE TIME; INTRON; LYSOSOME; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; RNA TRANSLATION; RNA TRANSPORT;

ALTERNATIVE SPLICING; ANIMALS; CELL NUCLEUS; CHO CELLS; CRICETINAE; CYTOPLASM; EXONS; INTRONS; LYSOSOMES; PRECIPITIN TESTS; PROTEIN BIOSYNTHESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; RNA; RNA, MESSENGER; SUBCELLULAR FRACTIONS; TETRAHYDROFOLATE DEHYDROGENASE; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0141532208     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212746200     Document Type: Article

References (60)

1. Brinster, R. L., Allen, J. M., Behringer, R. R., Gelinas, R. E. & Palmiter, R. D. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 836-840
2. Buchman, A. R. & Berg, P. (1988) Mol. Cell. Biol. 8, 4395-4405
3. Collis, P., Antoniou, M. & Grosveld, F. (1990) EMBO J. 9, 233-240
4. Huang, M. T.-F. & Gorman, C. M. (1990) Nucleic Acids Res. 18, 937-947
5. Pandey, N. B., Chodchoy, N., Liu, T. J. & Marzluff, W. F. (1990) Nucleic Acids Res. 18, 3161-3170
6. Nesic, D., Chang, J. & Maquat, L. E. (1993) Mol. Cell. Biol. 13, 3359-3369
7. Nesic, D. & Maquat, L. E. (1993) Genes Dev. 8, 363-375
8. Lou, H., Gagel, R. F. & Berget, S. M. (1996) Genes Dev. 10, 208-219
9. Cooke, C., Hans, H. & Alwine, J. C. (1999) Mol. Cell. Biol. 19, 4971-4979
10. Ryu, W.-S. & Mertz, J. E. (1989) J. Virol. 63, 4386-4394
11. Meric, F., Searfoss, A. M., Wormington, M. & Wolffe, A. P. (1996) J. Biol. Chem. 271, 30804-30810
12. Luo, M. J. & Reed, R. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14937-14942
13. Le Hir, H., Izaurralde, E., Maquat, L. E. & Moore, M. J. (2000) EMBO J. 19, 6860-6869
14. Bouvet, P. & Wolffe, A. P. (1994) Cell 77, 931-941
15. Braddock, M., Muckenthaler, M., White, M. R. H., Thorburn, A. M., Sommerville, J., Kingsman, A. J. & Kingsman, S. M. (1994) Nucleic Acids Res. 22, 5255-5264
16. Zhang, J., Sun, X., Qian, Y. & Maquat, L. E. (1998) RNA 4, 801-815
17. Sun, X., Moriarty, P. M. & Maquat, L. E. (2000) EMBO J. 19, 4734-4744
18. Gasser, C. S., Simonsen, C. C., Schilling, J. W. & Schimke, R. T. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 6522-6526
19. Venolia, L., Urlaub, G. & Chasin, L. A. (1987) Somat. Cell. Genet. 13, 491-504
20. Crouse, G. F., Stivaletta, L. A. & Smith, M. L. (1988) Nucleic Acids Res. 16, 7025-7042
21. Kessler, O., Jiang, Y. & Chasin, L. A. (1993) Mol. Cell. Biol. 13, 6211-6222
22. Gossen, M. & Bujard, H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5547-5551
23. Kessler, O. & Chasin, L. A. (1996) Mol. Cell. Biol. 16, 4426-4435
24. Urlaub, G., Mitchell, P. J., Kas, E., Funanage, V. L., Myoda, T. T & Hamlin, J. L. (1986) Somat. Cell Mol. Genet. 12, 555-566
25. Wigler, M., Pellicer, A., Silverstein, S., Axel, A., Urlaub, G. & Chasin, L. A. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 1373-1376
26. Luskey, M. & Botchan, M. R. (1984) Cell 36, 391-401
27. Noé, V., Alemany, C., Chasin, L. A. & Ciudad, C. J. (1998) Oncogene 16, 1931-1938
28. Laemmli, U. K. (1970) Nature 227, 680-685
29. Sallés, F. J., Richards, W. G. & Strickland, S. (1999) Methods 17, 38-45
30. Noé, V., Ciudad, C. J. & Chasin, L. A. (1999) J. Biol. Chem. 274, 27807-27814
31. Lee, F., Mulligan, R., Berg, P. & Ringold, G. (1981) Nature 294, 228-232
32. Rousseau, D., Kaspar, R., Rosenwald, I. Gehrke, L., & Sonenberg, N. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1065-1070
33. Hamm, J. & Mattaj, I. W. (1989) EMBO J. 8, 4153-4158
34. Muckenthaler, M., Gunkel, N., Stripecke, R. & Hentze, M. W. (1997). RNA 3, 983-995
35. Preiss, T., Muckenthaler, M. & Hentze, M. W. (1998) RNA 4, 1321-1331
36. de Moor, C. H. & Richter, J. D. (2001) Int. Rev. Cytol. 203, 567-608
37. Matsumoto, K., Wassarman, K. M. & Wolffe, A. P. (1998) EMBO J. 17, 2107-2121
38. Gray, N. K. & Wickens, M. (1998) Annu. Rev. Cell Dev. Biol. 14, 399-458
39. Preiss, T. & Hentze, M. W. (1999) Curr. Opin. Genet. Dev. 9, 515-521
40. Gingras, A. C., Raught, B. & Sonenberg, N. (2001) Genes Dev. 15, 807-826
41. Dice, J. F. (1987) FASEB J. 1, 349-357
42. Seglen, P. O., Grinde, B. & Solheim, A. E (1979). Eur. J. Biochem. 95, 215-335
43. Moriyama, T., Sather, S. K., Mcgee, T. P. & Simoni, R. D. (1998) J. Biol. Chem. 273, 22037-22043
44. Lee, D. H. & Goldberg, A. L. (1996) J. Biol. Chem. 271, 27280-27284
45. Nott, A., Meislin, S. H. & Moore, M. J. (2003) RNA 9, 607-617
46. Lu, S. & Cullen, B. R. (2003) RNA 9, 618-630
47. Hawkins, J. D. (1988) Nucleic Acids Res. 16, 9893-9908
48. Niwa, M., Rose, S. D. & Berget, S. M. Genes Dev. (1990) 4, 1552-1559
49. Niwa, M. & Berget, S. M. Gene Expr. (1991) 1, 5-14
50. Eckner, R., Ellmeier, W. & Birnstiel, M. L. (1991) EMBO J. 10, 3513-3522
51. Huang, Y. & Carmichael, G. G. (1996) Mol. Cell. Biol. 16, 1534-1542
52. Pasquinelli, A. E., Ernst, R. K., Lund, E., Grimm, C., Zapp, M. L., Rekosh, D., Hammarskjold, M. L. & Dahlberg, J. E. (1997) EMBO J. 16, 7500-7510
53. Ullman, K. S., Shah, S., Powers, M. A. & Forbes, D. J. (1999) Mol. Biol. Cell 10, 649-664
54. Rodrigues, J. P., Rode, M., Gatfield, D., Blencowe, B. J., Carmo-Fonseca, M. & Izaurralde, E. (2001). Proc. Natl. Acad. Sci. U. S. A.; 98, 1030-1035
55. Maquat, L. E. & Li, X. (2001) RNA 7, 445-456
56. Brocke, K. S., Neu-Yilik, G., Gehring, N. H., Hentze, M. W. & Kulozik, A. E. (2002) Hum. Mol. Genet. 11, 331-335
57. Standart, N. & Jackson, R. (1994) Curr. Biol. 4, 939-941
58. Wickner, S., Maurizi, M. R. & Gottesman, S. (1999) Science 286, 1888-1893
59. Terlecky, S. R. & Dice, J. F. (1993) J. Biol. Chem. 268, 23490-23495
60. Salvador, N., Aguado, C., Horst, M. & Knecht, E. (2000) J. Biol. Chem. 275, 27447-27456