Tertiary structure of thiopurine methyltransferase from Pseudomonas syringae, a bacterial orthologue of a polymorphic, drug-metabolizing enzyme

Journal of Molecular Biology

Volumn 333, Issue 3, 2003, Pages 573-585

  Scheuermann, Thomas H ^a   Lolis, Elias ^b   Hodsdon, Michael E ^b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug metabolism; Methyltransferase; NMR; S adenosylmethionine; Tertiary structure

Indexed keywords

DRUG METABOLIZING ENZYME; ENZYME; MERCAPTOPURINE; METHYLTRANSFERASE; S ADENOSYLMETHIONINE; THIOPURINE METHYLTRANSFERASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM; CATALYSIS; ENZYME ACTIVITY; METHYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; PSEUDOMONAS SYRINGAE; SEQUENCE HOMOLOGY;

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS SYRINGAE;

EID: 0141527466     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.08.039     Document Type: Article

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