The telomerase/vault-associated protein TEP1 is required for vault RNA stability and its association with the vault particle

Journal of Cell Biology

Volumn 152, Issue 1, 2001, Pages 157-164

  Kickhoefer, Valerie A ^a   Liu, Yie ^b   Kong, Lawrence B ^a   Snow, Bryan E ^b   Stewart, Phoebe L ^a   Harrington, Lea ^b   Rome, Leonard H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cryo EM; Mouse embryonic stem cells; RNA stability; TEP1; Vaults

Indexed keywords

PROTEIN SUBUNIT; PROTEIN TEP1; RIBONUCLEOPROTEIN; TELOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PURIFICATION; ENZYME STRUCTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA STABILITY;

ANIMALS; CARRIER PROTEINS; CRYOELECTRON MICROSCOPY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RNA STABILITY; TELOMERASE; VAULT RIBONUCLEOPROTEIN PARTICLES;

ANIMALIA;

EID: 0035825120     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.152.1.157     Document Type: Article

References (48)

1. Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell
2. Cryo-electron microscopy of viruses
3. Reconstitution of human telomerase activity in vitro
4. Functional characterization and developmental regulation of mouse telomerase RNA
5. Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy
6. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression
7. Secondary structure of vertebrate telomerase RNA
8. Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy
9. Telomere length regulation
10. Characterization of the sea urchin major vault protein: A possible role for vault ribonucleoprotein particles in nucleocytoplasmic transport
11. A mammalian telomerase-associated protein
12. Human telomerase contains evolutionarily conserved catalytic and structural subunits
13. Recombinant major vault protein is targeted to neuritic tips of PC12 cells
14. The mouse telomerase RNA 5″-end lies just upstream of the telomerase template sequence
15. Functional requirement of p23 and hsp90 in telomerase complexes
16. Isolation and characterization of a novel ribonucleoprotein particle: Large structures contain a single species of small RNA
17. Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry
18. Vault ribonucleoprotein particles from rat and bull-frog contain a related small RNA that is transcribed by RNA polymerase III
19. Vaults are the answer, what is the question?
20. Vaults are up-regulated in multidrug-resistant cancer cell lines
21. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase
22. Vaults and telomerase share a common subunit, TEP1
23. Specific association of human telomerase activity with immortal cells and cancer
24. Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells
25. Structure of the vault, a ubiquitous cellular component
26. RNA location and modeling of a WD40 repeat domain within the vault
27. The levels of the RoRNPassociated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 protein
28. Identification of two RNA-binding proteins associated with human telomerase RNA
29. The telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo
30. Characterization of Sm-like proteins in yeast and their association with U6 snRNA
31. A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end
32. A telomerase component is defective in the human disease dyskeratosis congenita
33. TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family
34. Nucleolar localization signals of box H/ACA small nucleolar RNAs
35. A role for the yeast La protein in U6 snRNP assembly: Evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts
36. Identification of a nonprocessive telomerase activity from mouse cells
37. Unlocking vaults: Organelles in search of a function
38. Convergent transcripts of the yeast PRP38-SMD1 locus encode two essential splicing factors, including the D1 core polypeptide of small nuclear ribonucleoprotein particles
39. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin
40. The drug resistance-related protein LRP is the human major vault protein
41. One-step affinity purification protocol for human telomerase
42. QVIEW: Software for rapid selection of particles from digital electron micrographs
43. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
44. A new generation of the IMAGIC image processing system
45. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
46. U snRNP assembly in yeast involves the La protein
47. Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels
48. Cloning and characterization of human and mouse telomerase RNA gene promoter sequences