Inhalant nitrite exposure alters mouse hepatic angiogenic gene expression

Biochemical and Biophysical Research Communications

Volumn 310, Issue 2, 2003, Pages 439-445

  Tran, Doanh C ^a   Yeh, Kai Chuan ^a   Brazeau, Daniel A ^a   Fung, Ho Leung ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Flk 1; Isobutyl nitrite; J774; Nitric oxide; Nitrite; Popper; RT PCR; Vascular endothelial growth factor; VEGFR 2

Indexed keywords

LIVER PROTEIN; LUNG RESISTANCE PROTEIN; MESSENGER RNA; NITRITE; PEPTIDES AND PROTEINS; SMAD5 PROTEIN; SMAD7 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EXPOSURE; GENE EXPRESSION REGULATION; INCUBATION TIME; INDUCED MUTATION; LETHAL DOSE; MACROPHAGE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 0141459002     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.09.041     Document Type: Article

References (40)

1. Brunton T.L. On the use of nitrite of amyl in angina pectoris. Lancet. 2:1867;97.
2. Lembo N.J., Dell'Italia L.J., Crawford M.H., O'Rourke R.A. Bedside diagnosis of systolic murmurs. N. Engl. J. Med. 318:1988;1572-1578.
3. United States Pharmacopeial Convention, USP DI, ed., The United States Pharmacopeial Convention, Inc., Rockville, MD, 1998.
4. Haverkos H.W. Nitrite inhalant abuse and AIDS-related Kaposi's sarcoma. J. Acquir. Immune Def. Syndr. 3:1990;S47-S50.
5. Marmor M., Friedman-Kien A.E., Laubenstein L., Byrum R.D., William D.C., D'Onofrio S., Dubin N. Risk factors for Kaposi's sarcoma in homosexual men. Lancet. 1:1982;1083-1087.
6. Folkman J. What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. 82:1990;4-6.
7. Ferrara N., Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr. Rev. 18:1997;4-25.
8. Arasteh K., Hannah A. The role of vascular endothelial growth factor (VEGF) in AIDS-related Kaposi's sarcoma. Oncologist. 5:2000;28-31.
9. Neufeld G., Cohen T., Gengrinovitch S., Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. Faseb J. 13:1999;9-22.
10. Jozkowicz A., Cooke J.P., Guevara I., Huk I., Funovics P., Pachinger O., Weidinger F., Dulak J. Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovasc. Res. 51:2001;773-783.
11. Kimura H., Ogura T., Kurashima Y., Weisz A., Esumi H. Effects of nitric oxide donors on vascular endothelial growth factor gene induction. Biochem. Biophys. Res. Commun. 296:2002;976-982.
12. Soderberg L.S. Increased tumor growth in mice exposed to inhaled isobutyl nitrite. Toxicol. Lett. 104:1999;35-41.
13. Soderberg L.S., Barnett J.B. Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide. J. Leukoc. Biol. 57:1995;135-140.
14. Soderberg L.S., Barnett J.B. Inhaled isobutyl nitrite compromises T-dependent, but not T-independent, antibody induction. Int. J. Immunopharmacol. 15:1993;821-827.
15. Soderberg L.S. T cell functions are impaired by inhaled isobutyl nitrite through a T-independent mechanism. Toxicol. Lett. 70:1994;319-329.
16. Fryer H.J., Davis G.E., Manthorpe M., Varon S. Lowry protein assay using an automatic microtiter plate spectrophotometer. Anal. Biochem. 153:1986;262-266.
17. Kielbasa W.B., Bauer J.A., Fung H.L. Analysis of isobutyl nitrite inhalant in rat and human blood: application for pharmacokinetic investigations. J. Chromatogr. B. Biomed. Sci. Appl. 734:1999;83-89.
18. Kielbasa W., Fung H.L. Nitrite inhalation in rats elevates tissue NOS III expression and alters tyrosine nitration and phosphorylation. Biochem. Biophys. Res. Commun. 275:2000;335-342.
19. Wang E.Q., Lee W.I., Brazeau D., Fung H.L. cDNA microarray analysis of vascular gene expression after nitric oxide donor infusions in rats: implications for nitrate tolerance mechanisms. AAPS Pharmsci. 4:2002;E10.
20. Manley P.W., Martiny-Baron G., Schlaeppi J.M., Wood J.M. Therapies directed at vascular endothelial growth factor. Expert Opin. Invest. Drugs. 11:2002;1715-1736.
21. Dulak J., Jozkowicz A. Regulation of vascular endothelial growth factor synthesis by nitric oxide: facts and controversies. Antioxid. Redox. Signal. 5:2003;123-132.
22. Benoit H., Jordan M., Wagner H., Wagner P.D. Effect of NO, vasodilator prostaglandins, and adenosine on skeletal muscle angiogenic growth factor gene expression. J. Appl. Physiol. 86:1999;1513-1518.
23. Kowaluk E.A., Fung H.L. Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct. J. Pharmacol. Exp. Ther. 259:1991;519-525.
24. Soderberg L.S., Roy A., Flick J.T., Barnett J.B. Nitrite inhalants spontaneously liberate nitric oxide , which is not responsible for the immunotoxicity in C57BL/6 mice. Int. J. Immunopharmacol. 22:2000;151-157.
25. Wilting J., Birkenhager R., Eichmann A., Kurz H., Martiny-Baron G., Marme D., McCarthy J.E., Christ B., Weich H.A. VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane. Dev. Biol. 176:1996;76-85.
26. Duval M., Bedard-Goulet S., Delisle C., Gratton J.P. Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells. J. Biol. Chem. 278:2003;20091-20097.
27. Partanen T.A., Alitalo K., Miettinen M. Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors. Cancer. 86:1999;2406-2412.
28. Yang X., Castilla L.H., Xu X., Li C., Gotay J., Weinstein M., Liu P.P., Deng C.X. Angiogenesis defects mesenchymal apoptosis in mice lacking SMAD5. Development. 126:1999;1571-1580.
29. Ten Dijke P., Goumans M.J., Itoh F., Itoh S. Regulation of cell proliferation by Smad proteins. J. Cell. Physiol. 191:2002;1-16.
30. Kamisaki Y., Wada K., Bian K., Balabanli B., Davis K., Martin E., Behbod F., Lee Y.C., Murad F. An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc. Natl. Acad. Sci. USA. 95:1998;11584-11589.
31. Kimura H., Esumi H. Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochim. Pol. 50:2003;49-59.
32. Barton P.J., Birks E.J., Felkin L.E., Cullen M.E., Koban M.U., Yacoub M.H. Increased expression of extracellular matrix regulators TIMP1 and MMP1 in deteriorating heart failure. J. Heart Lung Transplant. 22:2003;738-744.
33. Singhal S., Wiewrodt R., Malden L.D., Amin K.M., Matzie K., Friedberg J., Kucharczuk J.C., Litzky L.A., Johnson S.W., Kaiser L.R., Albelda S.M. Gene expression profiling of malignant mesothelioma. Clin. Cancer Res. 9:2003;3080-3097.
34. Bertucci F., Viens P., Hingamp P., Nasser V., Houlgatte R., Birnbaum D. Breast cancer revisited using DNA array-based gene expression profiling. Int. J. Cancer. 103:2003;565-571.
35. Yuan A., Yu C.J., Luh K.T., Chen W.J., Lin F.Y., Kuo S.H., Yang P.C. Quantification of VEGF mRNA expression in non-small cell lung cancer using a real-time quantitative reverse transcription-PCR assay and a comparison with quantitative competitive reverse transcription-PCR. Lab. Invest. 80:2000;1671-1680.
36. Snider J.V., Wechser M.A., Lossos I.S. Human disease characterization: real-time quantitative PCR analysis of gene expression. Drug Discov. Today. 6:2001;1062-1067.
37. Selvey S., Thompson E.W., Matthaei K., Lea R.A., Irving M.G., Griffiths L.R. Beta-actin - an unsuitable internal control for RT-PCR. Mol. Cell. Probes. 15:2001;307-311.
38. Schmittgen T.D., Zakrajsek B.A. Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. J. Biochem. Biophys. Methods. 46:2000;69-81.
39. Graven K.K., McDonald R.J., Farber H.W. Hypoxic regulation of endothelial glyceraldehyde-3-phosphate dehydrogenase. Am. J. Physiol. 274:1998;C347-C355.
40. Bereta J., Bereta M. Stimulation of glyceraldehyde-3-phosphate dehydrogenase mRNA levels by endogenous nitric oxide in cytokine-activated endothelium. Biochem. Biophys. Res. Commun. 217:1995;363-369.