메뉴 건너뛰기




Volumn 27, Issue 2-3, 2003, Pages 295-302

Anergy and suppression as coexistent mechanisms for the maintenance of peripheral T cell tolerance

Author keywords

Anergy; CD4+ T cell; Peripheral tolerance; Regulatory T cell; Superantigen; Suppression

Indexed keywords

BIOLOGICAL MARKER; CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 0141457196     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:27:2-3:295     Document Type: Review
Times cited : (8)

References (48)
  • 1
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler JW, Roehm N, Marrack P: T cell tolerance by clonal elimination in the thymus. Cell 1987;49:273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 2
    • 0025693909 scopus 로고
    • Peripheral clonal elimination of functional T cells
    • Jones LA, Chin LT, Longo DL, Kruisbeek AM: Peripheral clonal elimination of functional T cells. Science 1990;250:1726-1729.
    • (1990) Science , vol.250 , pp. 1726-1729
    • Jones, L.A.1    Chin, L.T.2    Longo, D.L.3    Kruisbeek, A.M.4
  • 3
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • Webb S, Morris C, Sprent J: Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 1990;63:1249-1256.
    • (1990) Cell , vol.63 , pp. 1249-1256
    • Webb, S.1    Morris, C.2    Sprent, J.3
  • 4
    • 0024338344 scopus 로고
    • Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls- Ia expressing cells
    • Rammensee HG, Kroschewski R, Frangoulis B: Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls- Ia expressing cells. Nature 1989;339:541-544.
    • (1989) Nature , vol.339 , pp. 541-544
    • Rammensee, H.G.1    Kroschewski, R.2    Frangoulis, B.3
  • 5
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH: A cell culture model for T lymphocyte clonal anergy. Science 1990;248:1349-1356.
    • (1990) Science , vol.248 , pp. 1349-1356
    • Schwartz, R.H.1
  • 6
    • 0030833571 scopus 로고    scopus 로고
    • T cell clonal anergy
    • Schwartz RH: T cell clonal anergy. Curr Opin Immunol 1997;9:351-357.
    • (1997) Curr Opin Immunol , vol.9 , pp. 351-357
    • Schwartz, R.H.1
  • 8
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M, Toda M, Sakaguchi N, Sakaguchi S: Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 1996;184:387-396.
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 9
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M: Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 10
    • 0031939403 scopus 로고    scopus 로고
    • CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • Suri-Payer E, Amar AZ, Thornton AM, Shevach EM: CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol 1998;160:1212-1218.
    • (1998) J Immunol , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 11
    • 0025036420 scopus 로고
    • Self-reactive T cells can escape clonal deletion in T-cell receptor V beta 8.1 transgenic mice
    • Yui K, Komori S, Katsumata M, Siegel RM, Greene MI: Self-reactive T cells can escape clonal deletion in T-cell receptor V beta 8.1 transgenic mice. Proc Natl Acad Sci USA 1990;87:7135-7139.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7135-7139
    • Yui, K.1    Komori, S.2    Katsumata, M.3    Siegel, R.M.4    Greene, M.I.5
  • 12
    • 0026011292 scopus 로고
    • Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice
    • Frankel WN, Rudy C, Coffin JM, Huber BT: Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice. Nature 1991;349:526-528.
    • (1991) Nature , vol.349 , pp. 526-528
    • Frankel, W.N.1    Rudy, C.2    Coffin, J.M.3    Huber, B.T.4
  • 13
    • 0024585726 scopus 로고
    • Restricted tissue distribution of Mls-1a determinants. Stimulation of Mls-1a-reactive T cells by B cells but not by dendritic cells or macrophages
    • Webb SR, Okamoto A, Ron Y, Sprent J: Restricted tissue distribution of Mls-1a determinants. Stimulation of Mls-1a-reactive T cells by B cells but not by dendritic cells or macrophages. J Exp Med 1989;169:1-12.
    • (1989) J Exp Med , vol.169 , pp. 1-12
    • Webb, S.R.1    Okamoto, A.2    Ron, Y.3    Sprent, J.4
  • 15
    • 0026934727 scopus 로고
    • Factors influencing the fate of T cells responding to Mls antigens
    • Webb SR, O'Rourke AM, Sprent J: Factors influencing the fate of T cells responding to Mls antigens. Semin Immunol 1992;4:329-336.
    • (1992) Semin Immunol , vol.4 , pp. 329-336
    • Webb, S.R.1    O'Rourke, A.M.2    Sprent, J.3
  • 17
    • 0025921599 scopus 로고
    • A characteristic Mls-1a response precedes Mls-1a anergy in vivo
    • Dannecker G, Mecheri S, Staiano-Coico L, Hoffmann MK: A characteristic Mls-1a response precedes Mls-1a anergy in vivo. J Immunol 1991;146:2083-2087.
    • (1991) J Immunol , vol.146 , pp. 2083-2087
    • Dannecker, G.1    Mecheri, S.2    Staiano-Coico, L.3    Hoffmann, M.K.4
  • 18
    • 0026068601 scopus 로고
    • Programmed cell death and extrathymic reduction of Vbeta8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
    • Kawabe Y, Ochi A: Programmed cell death and extrathymic reduction of Vbeta8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature 1991;349:245-248.
    • (1991) Nature , vol.349 , pp. 245-248
    • Kawabe, Y.1    Ochi, A.2
  • 19
    • 0025767045 scopus 로고
    • Clonal expansion precedes anergy and death of V beta 8+ peripheral T cells responding to staphylococcal enterotoxin B in vivo
    • MacDonald HR, Baschieri S, Lees RK: Clonal expansion precedes anergy and death of V beta 8+ peripheral T cells responding to staphylococcal enterotoxin B in vivo. Eur J Immunol 1991;21:1963-1966.
    • (1991) Eur J Immunol , vol.21 , pp. 1963-1966
    • MacDonald, H.R.1    Baschieri, S.2    Lees, R.K.3
  • 20
    • 0025096425 scopus 로고
    • In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B
    • Rellahan BL, Jones LA, Kruisbeek AM, Fry AM, Matis LA: In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B. J Exp Med 1990;172:1091-1100.
    • (1990) J Exp Med , vol.172 , pp. 1091-1100
    • Rellahan, B.L.1    Jones, L.A.2    Kruisbeek, A.M.3    Fry, A.M.4    Matis, L.A.5
  • 21
    • 0031895319 scopus 로고    scopus 로고
    • Biochemical features of anergic T cells
    • Maier CC, Greene MI: Biochemical features of anergic T cells. Immunol Res 1998;17:133-140.
    • (1998) Immunol Res , vol.17 , pp. 133-140
    • Maier, C.C.1    Greene, M.I.2
  • 22
    • 0027259135 scopus 로고
    • Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells
    • Bhandoola A, Cho EA, Yui K, Saragovi HU, Greene MI, Quill H: Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells. J Immunol 1993;151:2355-2367.
    • (1993) J Immunol , vol.151 , pp. 2355-2367
    • Bhandoola, A.1    Cho, E.A.2    Yui, K.3    Saragovi, H.U.4    Greene, M.I.5    Quill, H.6
  • 23
    • 0028233802 scopus 로고
    • Delayed allograft rejection by T cell receptor V beta 8.1 transgenic mice peripherally tolerized to Mls-1
    • Bhandoola A, Bassiri H, Markmann JF, Yui K, Hashimoto Y, Greene MI: Delayed allograft rejection by T cell receptor V beta 8.1 transgenic mice peripherally tolerized to Mls-1. Eur J Immunol 1994;24:1710-1713.
    • (1994) Eur J Immunol , vol.24 , pp. 1710-1713
    • Bhandoola, A.1    Bassiri, H.2    Markmann, J.F.3    Yui, K.4    Hashimoto, Y.5    Greene, M.I.6
  • 24
    • 0032758689 scopus 로고    scopus 로고
    • Peripheral CD4+ T cell maturation recognized by increased expression of Thy-1/CD90 bearing the 6C10 carbohydrate epitope
    • Gui M, Wiest DL, Li J, Kappes D, Hardy RR, Hayakawa K: Peripheral CD4+ T cell maturation recognized by increased expression of Thy-1/CD90 bearing the 6C10 carbohydrate epitope. J Immunol 1999;163:4796-4804.
    • (1999) J Immunol , vol.163 , pp. 4796-4804
    • Gui, M.1    Wiest, D.L.2    Li, J.3    Kappes, D.4    Hardy, R.R.5    Hayakawa, K.6
  • 25
    • 0025918155 scopus 로고
    • Murine CD4+ T-cell subsets
    • Hayakawa K, Hardy RR: Murine CD4+ T-cell subsets. Immunol Rev 1991;123:145-168.
    • (1991) Immunol Rev , vol.123 , pp. 145-168
    • Hayakawa, K.1    Hardy, R.R.2
  • 26
    • 0024213632 scopus 로고
    • Murine CD4+ T cell subsets defined
    • Hayakawa K, Hardy RR: Murine CD4+ T cell subsets defined. J Exp Med 1988;168:1825-1838.
    • (1988) J Exp Med , vol.168 , pp. 1825-1838
    • Hayakawa, K.1    Hardy, R.R.2
  • 28
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP: CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 1992;356:607-609.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 29
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins MK, Schwartz RHH: Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J Exp Med 1987;165:302-319.
    • (1987) J Exp Med , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.H.H.2
  • 30
    • 0023266396 scopus 로고
    • Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: Specific induction of a long-lived state of proliferative nonresponsiveness
    • Quill H, Schwartz RH: Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness. J Immunol 1987;138:3704-3712.
    • (1987) J Immunol , vol.138 , pp. 3704-3712
    • Quill, H.1    Schwartz, R.H.2
  • 31
    • 0026687519 scopus 로고
    • Reversal of in vitro T cell clonal anergy by IL-2 stimulation
    • Beverly B, Kang SM, Lenardo MJ, Schwartz RH: Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Int Immunol 1992;4:661-671.
    • (1992) Int Immunol , vol.4 , pp. 661-671
    • Beverly, B.1    Kang, S.M.2    Lenardo, M.J.3    Schwartz, R.H.4
  • 32
    • 0027301903 scopus 로고
    • Altered protein tyrosine phosphorylation in anergic Th1 cells
    • Cho EA, Riley MP, Sillman AL, Quill H: Altered protein tyrosine phosphorylation in anergic Th1 cells. J Immunol 1993;151:20-28.
    • (1993) J Immunol , vol.151 , pp. 20-28
    • Cho, E.A.1    Riley, M.P.2    Sillman, A.L.3    Quill, H.4
  • 33
    • 0027958565 scopus 로고
    • Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways
    • Gajewski TF, Qian D, Fields P, Fitch FW: Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways. Proc Natl Acad Sci USA 1994;91:38-42.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 38-42
    • Gajewski, T.F.1    Qian, D.2    Fields, P.3    Fitch, F.W.4
  • 34
    • 0026669383 scopus 로고
    • Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn
    • Quill H, Riley MP, Cho EA, Casnellie JE, Reed JC, Torigoe T: Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn. J Immunol 1992;149:2887-2893.
    • (1992) J Immunol , vol.149 , pp. 2887-2893
    • Quill, H.1    Riley, M.P.2    Cho, E.A.3    Casnellie, J.E.4    Reed, J.C.5    Torigoe, T.6
  • 35
    • 0029952223 scopus 로고    scopus 로고
    • Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways
    • DeSilva DR, Feeser WS, Tancula EJ, Scherle PA: Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways. J Exp Med 1996;183:2017-2023.
    • (1996) J Exp Med , vol.183 , pp. 2017-2023
    • DeSilva, D.R.1    Feeser, W.S.2    Tancula, E.J.3    Scherle, P.A.4
  • 36
    • 0029991920 scopus 로고    scopus 로고
    • Blocked Ras activation in anergic CD4+ T cells
    • Fields PE, Gajewski TF, Fitch FW: Blocked Ras activation in anergic CD4+ T cells. Science 1996;271:1276-1278.
    • (1996) Science , vol.271 , pp. 1276-1278
    • Fields, P.E.1    Gajewski, T.F.2    Fitch, F.W.3
  • 37
    • 0029975023 scopus 로고    scopus 로고
    • Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells
    • Li W, Whaley CD, Mondino A, Mueller DL: Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells. Science 1996;271:1272-1276.
    • (1996) Science , vol.271 , pp. 1272-1276
    • Li, W.1    Whaley, C.D.2    Mondino, A.3    Mueller, D.L.4
  • 38
    • 0028902752 scopus 로고
    • Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
    • Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN: Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 1995;267:515-518.
    • (1995) Science , vol.267 , pp. 515-518
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 39
    • 0027967385 scopus 로고
    • Partial T cell signaling: Altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy
    • Sloan-Lancaster J, Shaw AS, Rothbard JB, Allen PM: Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy. Cell 1994;79:913-922.
    • (1994) Cell , vol.79 , pp. 913-922
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothbard, J.B.3    Allen, P.M.4
  • 40
    • 0034700107 scopus 로고    scopus 로고
    • Suppressor T cells regulate the nonanergic cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vbeta 8.1 transgenic mice
    • Maeda H, Fujimoto S, Greene MI: Suppressor T cells regulate the nonanergic cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vbeta 8.1 transgenic mice. Proc Natl Acad Sci USA 2000;97:13,257-13,262.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13257-13262
    • Maeda, H.1    Fujimoto, S.2    Greene, M.I.3
  • 42
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen non-specific
    • Thornton AM, Shevach EM: Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen non-specific. J Immunol 2000;164:183-190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 43
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S: Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002;3:135-142.
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 44
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F: Regulatory T cells in the control of immune pathology. Nat Immunol 2001;2:816-822.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 45
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S: Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000;101:455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 46
    • 0035806289 scopus 로고    scopus 로고
    • Certified professionals: CD4(+)CD25(+) suppressor T cells
    • Shevach EM: Certified professionals: CD4(+)CD25(+) suppressor T cells. J Exp Med 2001;193:F41-46.
    • (2001) J Exp Med , vol.193
    • Shevach, E.M.1
  • 47
    • 0033526853 scopus 로고    scopus 로고
    • Anergy and cytokine-mediated suppression as distinct superantigen- induced tolerance mechanisms in vivo
    • Miller C, Ragheb JA, Schwartz RH: Anergy and cytokine-mediated suppression as distinct superantigen- induced tolerance mechanisms in vivo. J Exp Med 1999;190:53-64.
    • (1999) J Exp Med , vol.190 , pp. 53-64
    • Miller, C.1    Ragheb, J.A.2    Schwartz, R.H.3
  • 48
    • 0006938439 scopus 로고
    • Peripheral Tolerance to the Azobenzenearsonate Hapten in V alpha 3.1 T cell Receptor Transgenic Mice
    • Saouaf SJ, Zerva L, Greene MI: Peripheral Tolerance to the Azobenzenearsonate Hapten in V alpha 3.1 T cell Receptor Transgenic Mice. Transgenics 1994;1:171-183.
    • (1994) Transgenics , vol.1 , pp. 171-183
    • Saouaf, S.J.1    Zerva, L.2    Greene, M.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.