Inhibition of NF-κB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis

Blood

Volumn 102, Issue 6, 2003, Pages 2259-2267

  Choi, Mira ^b   Rolle, Susanne ^b   Wellner, Maren ^b   Cardoso, M Cristina ^b   Scheidereit, Claus ^b   Luft, Friedrich C ^b   Kettritz, Ralph ^a  

^a FRANZ VOLHARD CLINIC   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PEPTIDE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; CHUK PROTEIN, HUMAN; GLUCOCORTICOID; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; PEPTIDE FRAGMENT; PROTEIN SERINE THREONINE KINASE;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; BINDING SITE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

APOPTOSIS; BINDING SITES; DEXAMETHASONE; GENE PRODUCTS, TAT; GLUCOCORTICOIDS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; I-KAPPA B KINASE; LIPOPOLYSACCHARIDES; NEUTROPHILS; NF-KAPPA B; PEPTIDE FRAGMENTS; PROTEIN-SERINE-THREONINE KINASES;

EID: 0141455956     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-09-2960     Document Type: Article

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