B-cell neoplasia associated gene with multiple splicing (BCMS): The candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions

Human Molecular Genetics

Volumn 10, Issue 12, 2001, Pages 1275-1285

  Wolf, Stephan ^a   Mertens, Daniel ^a   Schaffner, Claudia ^a   Korz, Christian ^a   Döhner, Hartmut ^b   Stilgenbauer, Stephan ^b   Lichter, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; ZINC FINGER PROTEIN;

ARTICLE; B LYMPHOCYTE; CHROMOSOME 13Q; CHROMOSOME BAND; CHROMOSOME DELETION 13; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; EXON; GENE LOCATION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMOGENESIS; MANTLE CELL LYMPHOMA; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN VARIANT; RNA SPLICING; SEQUENCE ANALYSIS; TISSUE SPECIFICITY; TUMOR SUPPRESSOR GENE;

EID: 0035364954     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.12.1275     Document Type: Article

References (29)

1. Chronic lymphocytic leukemia - An accumulative disease of immunologically incompetent lymphocytes
2. Chronic lymphocytic leukemia
3. Genomic aberrations predict survival of patients with B-cell chronic lymphocytic leukemia
4. Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma
5. Frequent clonal abnormalities of chromosome band 13q14 in in B-cell chronic lymphocytic leukemia: Multible clones, subclones and nonclonal alterations in 82 midwestern patients
6. Non-random chromosomal aberrations in chronic lymphocytic leukemia revealed by polyclonal B cell-mitogen stimulation
7. Trisomy 12 defines a group of CLL with atypical morphology: Correlation between cytogenetic, clinical and laboratory features in 544 patients
8. t(11;14)-positive mantle cell lymphomas exhibit complex karyotypes and share similarities with B-cell chronic lymphocytic leukemia
9. Evidence for a new tumor suppressor locus (DBM) in human B-cell neoplasia telomeric to the retinoblastoma gene
10. Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia
11. Heterogenity of deletions involving RB-1 and the D13S25 locus in B-cell chronic lymphocytic leukemia revealed by FISH
12. Construction of a 780 kb PAC, BAC and cosmid contig encompassing the minimal deletion region involved in B cell chronic lymphocytic leukemia at 13q14.3
13. Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia
14. Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia
15. Detailed molecular delineation of 13q14.3 loss in B-cell chronic lymphocytic leukemia
16. Deletion cartography around the D13S25 locus in B cell chronic lymphocytic leukemia and accurate mapping of the involved tumor suppressor gene
17. A cosmid and cDNA fine physical map of human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new tumor suppressor gene LEU5
18. BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle cell lymphoma localized at 13q14.3, has an independently expressed homolog on 1p22-p31, BCMSUN-like
19. Exclusion of LEU1 and LEU2 as tumor suppressor genes in 13q14.3-deleted B-CLL
20. Potential role for concurrent abnormalities of the cyclin D1, p16CDKN2 and p15CDKN2B genes in certain B cell non-Hodgkin's lymphomas. Functional studies in a cell line (Granta 519)
21. Establishment of a karyotypically normal B-chronic lymphocytic leukemia cell line; evidence of leukemic origin by immunoglobulin gene rearrangement
22. Two new cell lines from B-prolymphocytic leukaemia: Characterization by morphology, immunological markers, karyotype and Ig gene rearrangement
23. Statistical features of human exons and their flanking regions
24. A sequence compilation and comparison of exons that are alternatively spliced in neurons
25. The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
26. The host gene for intronic U17 small nucleolar RNAs in mammals has no protein-coding potential and is a member of the 5′-terminal oligopyrimidine gene family
27. Isolation of a testis specific cDNA on chromosome 17q from a region adjacent to the breakpoint of t(12;17) observed in a patient with acampomelic campomelic dysplasia and sex reversal
28. Exon amplification from complete libraries of genomic DNA using a novel phage vector with automatic plasmid excision facility: Application to the mouse neurofibromatosis-1 locus
29. Basic local alignment search tool