-
1
-
-
0037304536
-
Thymic selection revisited: How essential is it?
-
Von Boehmer H., et al. Thymic selection revisited: how essential is it? Immunol. Rev. 191:2003;62-78.
-
(2003)
Immunol. Rev.
, vol.191
, pp. 62-78
-
-
Von Boehmer, H.1
-
2
-
-
0037191792
-
Self-recognition promotes the foreign antigen sensitivity of naïve T lymphocytes
-
Stefanova I., et al. Self-recognition promotes the foreign antigen sensitivity of naïve T lymphocytes. Nature. 420:2002;429-434.
-
(2002)
Nature
, vol.420
, pp. 429-434
-
-
Stefanova, I.1
-
3
-
-
0029662223
-
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex
-
Garcia K.C., et al. An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science. 274:1996;209-219.
-
(1996)
Science
, vol.274
, pp. 209-219
-
-
Garcia, K.C.1
-
4
-
-
0029855347
-
Structure of the complex between human T-cell receptor, viral peptide and HLA-A2
-
Garboczi D.N., et al. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:1996;134-141.
-
(1996)
Nature
, vol.384
, pp. 134-141
-
-
Garboczi, D.N.1
-
5
-
-
18344405559
-
Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
-
Ding Y.H., et al. Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. Immunity. 8:1998;403-411.
-
(1998)
Immunity
, vol.8
, pp. 403-411
-
-
Ding, Y.H.1
-
6
-
-
0033165928
-
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical
-
Ding Y.H., et al. Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity. 11:1999;45-56.
-
(1999)
Immunity
, vol.11
, pp. 45-56
-
-
Ding, Y.H.1
-
7
-
-
0033679767
-
A functional hot spot for antigen recognition in a superagonist TCR/MHC complex
-
Degano M., et al. A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity. 12:2000;251-261.
-
(2000)
Immunity
, vol.12
, pp. 251-261
-
-
Degano, M.1
-
8
-
-
5944249467
-
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule
-
Reiser J.-B., et al. Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat. Immunol. 1:2000;291-297.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 291-297
-
-
Reiser, J.-B.1
-
9
-
-
18344394144
-
A T cell receptor CDR3β loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex
-
Reiser J.B., et al. A T cell receptor CDR3β loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex. Immunity. 16:2002;345-354.
-
(2002)
Immunity
, vol.16
, pp. 345-354
-
-
Reiser, J.B.1
-
10
-
-
0037029674
-
Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: A buried alloreactive mutation subtly alters peptide presentation substantially increasing V(β) Interactions
-
Luz J.G., et al. Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(β) Interactions. J. Exp. Med. 195:2002;1175-1186.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1175-1186
-
-
Luz, J.G.1
-
11
-
-
0037240790
-
A structural basis for the selection of dominant αβ T cell receptors in antiviral immunity
-
Kjer-Nielsen L., et al. A structural basis for the selection of dominant αβ T cell receptors in antiviral immunity. Immunity. 18:2003;53-64.
-
(2003)
Immunity
, vol.18
, pp. 53-64
-
-
Kjer-Nielsen, L.1
-
12
-
-
0037342030
-
CDR3 loop flexibility contributes to the degeneracy of TCR recognition
-
Reiser J.B., et al. CDR3 loop flexibility contributes to the degeneracy of TCR recognition. Nat. Immunol. 4:2003;241-247.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 241-247
-
-
Reiser, J.B.1
-
13
-
-
0033520962
-
The crystal structure of a T cell receptor in complex with peptide and MHC class II
-
Reinherz E.L., et al. The crystal structure of a T cell receptor in complex with peptide and MHC class II. Science. 286:1999;1913-1921.
-
(1999)
Science
, vol.286
, pp. 1913-1921
-
-
Reinherz, E.L.1
-
14
-
-
0034329441
-
Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1
-
Hennecke J., et al. Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1. EMBO J. 19:2000;5611-5624.
-
(2000)
EMBO J.
, vol.19
, pp. 5611-5624
-
-
Hennecke, J.1
-
15
-
-
0037018102
-
Structure of a complex of the human α/β T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): Insight into TCR cross-restriction and alloreactivity
-
Hennecke J., Wiley D.C. Structure of a complex of the human α/β T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity. J. Exp. Med. 195:2002;571-581.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 571-581
-
-
Hennecke, J.1
Wiley, D.C.2
-
17
-
-
0036082615
-
Structural and thermodynamic correlates of T cell signaling
-
Rudolph M.G., et al. Structural and thermodynamic correlates of T cell signaling. Annu. Rev. Biophys. Biomol. Struct. 31:2002;121-149.
-
(2002)
Annu. Rev. Biophys. Biomol. Struct.
, vol.31
, pp. 121-149
-
-
Rudolph, M.G.1
-
18
-
-
0036229026
-
Structural basis of T cell recognition of peptides bound to MHC molecules
-
Wang J.H., Reinherz E.L. Structural basis of T cell recognition of peptides bound to MHC molecules. Mol. Immunol. 38:2002;1039-1049.
-
(2002)
Mol. Immunol.
, vol.38
, pp. 1039-1049
-
-
Wang, J.H.1
Reinherz, E.L.2
-
19
-
-
0037237830
-
Not just any T cell receptor will do
-
Bankovich A.J., Garcia K.C. Not just any T cell receptor will do. Immunity. 18:2003;7-11.
-
(2003)
Immunity
, vol.18
, pp. 7-11
-
-
Bankovich, A.J.1
Garcia, K.C.2
-
20
-
-
0032171644
-
A very high level of crossreactivity is an essential feature of the T-cell receptor
-
Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol. Today. 19:1998;395-404.
-
(1998)
Immunol. Today
, vol.19
, pp. 395-404
-
-
Mason, D.1
-
21
-
-
0032549142
-
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen
-
Garcia K.C., et al. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science. 279:1998;1166-1172.
-
(1998)
Science
, vol.279
, pp. 1166-1172
-
-
Garcia, K.C.1
-
22
-
-
0033017466
-
Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor
-
Hare B.J., et al. Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor. Nat. Struct. Biol. 6:1999;574-581.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 574-581
-
-
Hare, B.J.1
-
23
-
-
0033103834
-
TCR binding to peptide-MHC stabilizes a flexible recognition interface
-
Willcox B.E., et al. TCR binding to peptide-MHC stabilizes a flexible recognition interface. Immunity. 10:1999;357-365.
-
(1999)
Immunity
, vol.10
, pp. 357-365
-
-
Willcox, B.E.1
-
24
-
-
0033613074
-
Thermodynamics of T cell receptor binding to peptide-MHC: Evidence for a general mechanism of molecular scanning
-
Boniface J.J., et al. Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11446-11451.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11446-11451
-
-
Boniface, J.J.1
-
25
-
-
0037306046
-
An evolutionary and structural perspective on T cell antigen receptor function
-
Malissen B. An evolutionary and structural perspective on T cell antigen receptor function. Immunol. Rev. 191:2003;7-27.
-
(2003)
Immunol. Rev.
, vol.191
, pp. 7-27
-
-
Malissen, B.1
-
26
-
-
0037470496
-
Antibody multispecificity mediated by conformational diversity
-
James L.C., et al. Antibody multispecificity mediated by conformational diversity. Science. 299:2003;1362-1367.
-
(2003)
Science
, vol.299
, pp. 1362-1367
-
-
James, L.C.1
-
27
-
-
0036793245
-
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
-
Lang H.L., et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat. Immunol. 3:2002;940-943.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 940-943
-
-
Lang, H.L.1
-
28
-
-
0035101372
-
Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: Distinct characteristics correlated with CD8 dependence
-
Guimezanes A., et al. Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence. Eur. J. Immunol. 31:2001;421-432.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 421-432
-
-
Guimezanes, A.1
-
29
-
-
0030855425
-
The three-dimensional structure of a T-cell antigen receptor Vα Vβ heterodimer reveals a novel arrangement of the Vβ domain
-
Housset D., et al. The three-dimensional structure of a T-cell antigen receptor Vα Vβ heterodimer reveals a novel arrangement of the Vβ domain. EMBO J. 16:1997;4205-4216.
-
(1997)
EMBO J.
, vol.16
, pp. 4205-4216
-
-
Housset, D.1
-
30
-
-
0030935007
-
The MHC reactivity of the T cell repertoire prior to positive and negative selection
-
Zerrahn J., et al. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell. 88:1997;627-636.
-
(1997)
Cell
, vol.88
, pp. 627-636
-
-
Zerrahn, J.1
-
31
-
-
0030846879
-
How many thymocytes audition for selection?
-
Merkenschlager M., et al. How many thymocytes audition for selection? J. Exp. Med. 186:1997;1149-1158.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1149-1158
-
-
Merkenschlager, M.1
-
32
-
-
0037089649
-
Predominant role of T cell receptor (TCR)-α chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system
-
Yokosuka T., et al. Predominant role of T cell receptor (TCR)-α chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system. J. Exp. Med. 195:2002;991-1001.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 991-1001
-
-
Yokosuka, T.1
-
33
-
-
0037089568
-
Structural basis of cytochrome c presentation by IE(k)
-
Fremont D.H., et al. Structural basis of cytochrome c presentation by IE(k). J. Exp. Med. 195:2002;1043-1052.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1043-1052
-
-
Fremont, D.H.1
-
34
-
-
0028675018
-
Are MHC-bound peptides a nuisance for positive selection?
-
Schumacher T.N., Ploegh H.L. Are MHC-bound peptides a nuisance for positive selection? Immunity. 1:1994;721-723.
-
(1994)
Immunity
, vol.1
, pp. 721-723
-
-
Schumacher, T.N.1
Ploegh, H.L.2
-
35
-
-
0032076119
-
Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes
-
Speir J.A., et al. Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes. Immunity. 8:1998;553-562.
-
(1998)
Immunity
, vol.8
, pp. 553-562
-
-
Speir, J.A.1
-
36
-
-
0035122708
-
The shaping of the T cell repertoire
-
Correia-Neves M., et al. The shaping of the T cell repertoire. Immunity. 14:2001;21-32.
-
(2001)
Immunity
, vol.14
, pp. 21-32
-
-
Correia-Neves, M.1
-
37
-
-
0037434974
-
Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
-
Treiner E., et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature. 422:2003;164-169.
-
(2003)
Nature
, vol.422
, pp. 164-169
-
-
Treiner, E.1
-
38
-
-
0030826423
-
Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove
-
Zeng Z., et al. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science. 277:1997;339-345.
-
(1997)
Science
, vol.277
, pp. 339-345
-
-
Zeng, Z.1
-
39
-
-
0030006049
-
Population biology of antigen presentation by MHC class I molecules
-
Parham P., Ohta T. Population biology of antigen presentation by MHC class I molecules. Science. 272:1996;67-74.
-
(1996)
Science
, vol.272
, pp. 67-74
-
-
Parham, P.1
Ohta, T.2
-
40
-
-
0000467109
-
High determinants density may explain the phenomenon of alloreactivity
-
Bevan M.J. High determinants density may explain the phenomenon of alloreactivity. Immunol. Today. 5:1984;128-130.
-
(1984)
Immunol. Today
, vol.5
, pp. 128-130
-
-
Bevan, M.J.1
-
41
-
-
0017598571
-
Hypothesis: Why do so many lymphocytes respond to major histocompatibility antigens?
-
Matzinger P., Bevan M.J. Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens? Cell. Immunol. 29:1977;1-5.
-
(1977)
Cell. Immunol.
, vol.29
, pp. 1-5
-
-
Matzinger, P.1
Bevan, M.J.2
-
42
-
-
0035879094
-
Major histocompatibility complex proteins and TCRs: Do they really go together like a horse and carriage?
-
Marrack P., et al. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? J. Immunol. 167:2001;617-621.
-
(2001)
J. Immunol.
, vol.167
, pp. 617-621
-
-
Marrack, P.1
-
43
-
-
0035993997
-
Comparative analysis of the CD8(+) T cell repertoires of H-2 class I wild-type/HLA-A2.1 and H-2 class I knockout/HLA-A2.1 transgenic mice
-
Firat H., et al. Comparative analysis of the CD8(+) T cell repertoires of H-2 class I wild-type/HLA-A2.1 and H-2 class I knockout/HLA-A2.1 transgenic mice. Int. Immunol. 14:2002;925-934.
-
(2002)
Int. Immunol.
, vol.14
, pp. 925-934
-
-
Firat, H.1
-
44
-
-
0034610976
-
The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules
-
Obst R., et al. The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules. J. Exp. Med. 191:2000;805-812.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 805-812
-
-
Obst, R.1
-
45
-
-
0037373993
-
Tritope model of restrictive recognition by the TCR
-
Cohn M. Tritope model of restrictive recognition by the TCR. Trends Immunol. 24:2003;127-131.
-
(2003)
Trends Immunol.
, vol.24
, pp. 127-131
-
-
Cohn, M.1
-
46
-
-
0035809315
-
Identification of a crucial energetic footprint on the α1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors
-
Baker B.M., et al. Identification of a crucial energetic footprint on the α1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors. J. Exp. Med. 193:2001;551-562.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 551-562
-
-
Baker, B.M.1
-
47
-
-
0036682133
-
Two-step binding mechanism for T-cell receptor recognition of peptide MHC
-
Wu L.C., et al. Two-step binding mechanism for T-cell receptor recognition of peptide MHC. Nature. 418:2002;552-556.
-
(2002)
Nature
, vol.418
, pp. 552-556
-
-
Wu, L.C.1
-
48
-
-
0034678142
-
Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes
-
Lee P.U., et al. Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes. J. Exp. Med. 191:2000;1355-1364.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1355-1364
-
-
Lee, P.U.1
-
49
-
-
0036469060
-
Unraveling hot spots in binding interfaces: Progress and challenges
-
DeLano W.L. Unraveling hot spots in binding interfaces: progress and challenges. Curr. Opin. Struct. Biol. 12:2002;14-20.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 14-20
-
-
DeLano, W.L.1
-
50
-
-
0028958601
-
Characterizing transition states in protein folding: An essential step in the puzzle
-
Fersht A.R. Characterizing transition states in protein folding: an essential step in the puzzle. Curr. Opin. Struct. Biol. 5:1995;79-84.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 79-84
-
-
Fersht, A.R.1
-
51
-
-
0029981188
-
Structure of the transition state for folding of a protein derived from experiment and simulation
-
Daggett V., et al. Structure of the transition state for folding of a protein derived from experiment and simulation. J. Mol. Biol. 257:1996;430-440.
-
(1996)
J. Mol. Biol.
, vol.257
, pp. 430-440
-
-
Daggett, V.1
-
52
-
-
0032474463
-
A mutational analysis of binding interactions in an antigen-antibody protein-protein complex
-
Dall-Acqua W., et al. A mutational analysis of binding interactions in an antigen-antibody protein-protein complex. Biochemistry. 37:1998;7981-7991.
-
(1998)
Biochemistry
, vol.37
, pp. 7981-7991
-
-
Dall-Acqua, W.1
-
53
-
-
0037452709
-
Binding of small molecules to an adaptive protein-protein interface
-
Arkin M.R., et al. Binding of small molecules to an adaptive protein-protein interface. Proc. Natl. Acad. Sci. U. S. A. 100:2003;1603-1608.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1603-1608
-
-
Arkin, M.R.1
-
54
-
-
0026244229
-
Molscript: A program to produce both detailed and schematic plots of protein structures
-
Kraulis P.J. Molscript: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:1991;946-950.
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
55
-
-
0030815133
-
Raster3D: Photorealistic molecular graphics
-
Merrit E.A., Bacon D.J. Raster3D: photorealistic molecular graphics. Methods Enzymol. 277:1997;505-524.
-
(1997)
Methods Enzymol.
, vol.277
, pp. 505-524
-
-
Merrit, E.A.1
Bacon, D.J.2
-
56
-
-
0028956603
-
Crystal structure of the β chain of a T cell antigen receptor
-
Bentley G.A., et al. Crystal structure of the β chain of a T cell antigen receptor. Science. 267:1995;1984-1987.
-
(1995)
Science
, vol.267
, pp. 1984-1987
-
-
Bentley, G.A.1
-
57
-
-
0032472057
-
Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody
-
Wang J., et al. Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J. 17:1998;10-26.
-
(1998)
EMBO J.
, vol.17
, pp. 10-26
-
-
Wang, J.1
-
58
-
-
0029417003
-
Crystal structure of the Vα domain of a T cell antigen receptor
-
Fields B.A., et al. Crystal structure of the Vα domain of a T cell antigen receptor. Science. 270:1995;1821-1824.
-
(1995)
Science
, vol.270
, pp. 1821-1824
-
-
Fields, B.A.1
-
59
-
-
0019301537
-
Use of H-2 mutations to quantitate alloreactivity: Alloreactivity is strongest against H-2 antigens which are closet to self
-
Pimsler M., Forman J. Use of H-2 mutations to quantitate alloreactivity: alloreactivity is strongest against H-2 antigens which are closet to self. Immunogenetics. 11:1980;111-121.
-
(1980)
Immunogenetics
, vol.11
, pp. 111-121
-
-
Pimsler, M.1
Forman, J.2
-
60
-
-
0018838791
-
Cytolytic T lymphocyte precursors reactive against mutant Kb alloantigens are as frequent as those reactive against a whole foreign haplotype
-
Widmer M.B., MacDonald H.R. Cytolytic T lymphocyte precursors reactive against mutant Kb alloantigens are as frequent as those reactive against a whole foreign haplotype. J. Immunol. 124:1980;48-51.
-
(1980)
J. Immunol.
, vol.124
, pp. 48-51
-
-
Widmer, M.B.1
MacDonald, H.R.2
-
61
-
-
84991133477
-
Specificity of virus-immune effector T cells for H-2K or H-2D compatible interactions: Implications for H-antigen diversity
-
Doherty P.C., et al. Specificity of virus-immune effector T cells for H-2K or H-2D compatible interactions: implications for H-antigen diversity. Transplant Rev. 29:1976;89-124.
-
(1976)
Transplant Rev.
, vol.29
, pp. 89-124
-
-
Doherty, P.C.1
-
62
-
-
0034723149
-
Canonical structures for the hypervariable regions of T cell αβ receptors
-
Al-Lazikani B., et al. Canonical structures for the hypervariable regions of T cell αβ receptors. J. Mol. Biol. 295:2000;979-995.
-
(2000)
J. Mol. Biol.
, vol.295
, pp. 979-995
-
-
Al-Lazikani, B.1
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