Does metabolic radiolabeling stimulate the stress response? Gene expression profiling reveals differential cellular responses to internal beta vs. external gamma radiation

FASEB Journal

Volumn 17, Issue 11, 2003, Pages 1470-1486

  Marko, Nicholas F ^a   Dieffenbach, Paul B ^a   Yan, Gai ^a   Ceryak, Susan ^a   Howell, Roger W ^b   McCaffrey, Timothy A ^a   Hu, Valerie W ^a,c  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

DNA damage; DNA microarray; Ionizing radiation; Radioisotopes; Sulfur 35 methionine

Indexed keywords

DNA FRAGMENT; METHIONINE S 35; RADIOISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; BETA RADIATION; CELL CYCLE; CELL DEATH; COLORECTAL CARCINOMA; DNA MICROARRAY; GAMMA RADIATION; GENE EXPRESSION PROFILING; GENE INDUCTION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; IONIZING RADIATION; ISOTOPE LABELING; METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRESS; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE;

BETA RAYS; CDC2 PROTEIN KINASE; CLUSTER ANALYSIS; DNA DAMAGE; GAMMA RAYS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; HUMANS; KINETICS; METHIONINE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RADIATION DOSAGE; RADIOACTIVE TRACERS; SULFUR RADIOISOTOPES; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 0043211850     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.02-1194com     Document Type: Article

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