Dihydroorotate dehydrogenase B of Enterococcus faecalis. Characterization and insights into chemical mechanism

Biochemistry

Volumn 38, Issue 40, 1999, Pages 13129-13137

  Marcinkeviciene, Jovita ^a   Tinney, Lisa M ^a   Wang, Kathy H ^a   Rogers, M John ^a   Copeland, Robert A ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE; DIMER; ISOENZYME; OROTIC ACID; OROTIC ACID DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ENZYME ASSAY; ENZYME BINDING; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBUNIT; NONHUMAN; OXIDATION REDUCTION REACTION; PH; PRIORITY JOURNAL; PROTON TRANSPORT; REACTION ANALYSIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYSIS; DEUTERIUM; ENTEROCOCCUS FAECALIS; FLAVIN MONONUCLEOTIDE; FLAVIN-ADENINE DINUCLEOTIDE; FLAVINS; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR SEQUENCE DATA; NAD; OXIDATION-REDUCTION; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SOLVENTS; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS;

EID: 0032880511     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990674q     Document Type: Article

References (41)

1. Chen, S. F., Perrella, F. W., Behrens, D. L., and Papp, L. M. (1992) Cancer Res. 52, 3521-3527.
2. Harder, A., and Haberkorn, A. (1989) Parasitol. Res. 76, 8-12.
3. Ruckermann, K., Fairbanks, L. D., Carrey, E. A., Hawrylowicz, C. M., Richards, D. F., Kirschbaum, B., and Simmonds, H. A. (1998) J. Biol. Chem. 273, 21682-21691.
4. Davis, J. P., Cain, G. A., Pitts, W. J., Magolda, R. L., and Copeland, R. A. (1996) Biochemistry 35, 1270-1273.
5. Krungkrai, J., Cerami, A., and Henderson, G. B. (1991) Biochemistry 30, 1934-1939.
6. Knecht, W., Altekruse, D., Rotgeri, A., Gonski, S., and Loffler, M. (1997) Protein Expression Purif. 10, 89-99.
7. Pascal, R. A., LeTrang, N., Cerami, A., and Walsh, C. T. (1983) Biochemistry 22, 171-178.
8. Copeland, R. A., Davis, J. P., Dowling, R. L., Lombardo, D., Murphy, K. B., and Patterson, T. A. (1995) Arch. Biochem. Biophys. 323, 79-86.
9. Pascal, R. A., and Walsh, C. T. (1984) Biochemistry 23, 2745-2752.
10. Hines, V., and Johnston, M. (1989) Biochemistry 28, 1227-1234.
11. Larsen, J. N., and Jensen, K. F. (1985) Eur. J. Biochem. 151, 59-65.
12. Andersen, P. S., Jansen, P. J. G., and Hammer, K. (1994) J. Bacteriol. 176, 3975-3982.
13. Rowland, P., Nielsen, F. S., Jensen, K. F., and Larsen, S. (1997) Structure 5, 239-252.
14. Rowland, P., Bjornberg, O., Nielsen, F., Jensen, K. F., and Larsen, S. (1998) Protein Sci. 7, 1269-1279.
15. Bjornberg, O., Rowland, P., Larsen, S., and Jensen, K. F. (1997) Biochemistry 36, 16197-16205.
16. Li, X., Weinstock, G. M., and Murray, B. E. (1995) J. Bacteriol. 177, 6866-6873.
17. Benkel, B. F., and Fong, Y. (1996) Genet. Anal. 13, 123-127.
18. Light, D. R., Walsh, C. T., and Marietta, M. A. (1980) Anal. Biochem. 109, 87-93.
19. Nielsen, F. S., Andersen, P. S., and Jensen, K. F. (1996) J. Biol. Chem. 271, 29359-29365.
20. Massey, V., Hofmann, T., and Palmer, G. (1962) J. Biol. Chem. 237, 3820-3828.
21. Copeland, R. A. (1994) Methods for protein analysis, pp 51-54, Chapman & Hall, New York and London.
22. Fibla, J., and Gonzalez, D. R. (1993) J. Biochem. Biophys. Methods 26, 87-93.
23. Orr, G. A., and Blanchard, J. S. (1994) Anal. Biochem. 142, 232-235.
24. Cleland, W. W. (1979) Methods Enzymol. 63, 103-138.
25. Vanoni, M. A., Wong, K. K., Ballou, D. P., and Blanchard J. S. (1990) Biochemistry 29, 5790-5796.
26. Batie, C. J., LaHaie, E.; and Ballou, D. P. (1987) J. Biol. Chem. 262, 1510-1518.
27. Gassner, G., Wang, L., Batie, C., and Ballou, D. P. (1994) Biochemistry 33, 12184-12193.
28. Singer, T. P., Gutman, M., and Massey, V. (1973) in Iron-sulfur proteins (Lovenberg, W., Ed.) Vol. 1, pp 285-294, Academic Press, New York.
29. Jorns, M. S. (1985) Biochemistry 24, 3189-3194.
30. Massey, V., and Hemmerich, P. (1980) Biochem. Soc. Trans. 8, 246-257.
31. Vanoni, M. A., Edmondson, D. E., Zanetti, G., and Curti, B. (1992) Biochemistry 31, 4613-4623.
32. Megran, D. W. (1992) Clin. Infect. Dis. 15, 63-71.
33. Kahler, A. E., and Switzer, R. L. (1996) J. Bacteriol. 178, 5013-5016.
34. Podschun, B., Jahnke, K., Schnackerz, K., and Cook, P. (1993) J. Biol. Chem. 268, 3407-3413.
35. Porter, D. J. T., Chestnut, W. G., Taylor, L. C. E., Merrill, B. M., and Spector, T. (1991) J. Biol. Chem. 266, 19988-19994.
36. Rosenbaum, K., Jahnke, K., Schnackerz, K. D., and Cook, P. F. (1998) Biochemistry 37, 9156-9159.
37. Quinn, D. M., and Sutton, L. D. (1991) in Enzyme mechanism from isotope effects (Cook, P. F., Ed.) pp 73-123, CRC Press, Boca Raton.
38. Correll, C. C., Batie, C. J., Ballou, D. P., and Ludwig, M. L. (1992) Science 258, 1604-1610.
39. Karplus, A. P., Daniels, M. J., and Herriott, J. R. (1991) Science 251, 60-66.
40. Cleland, W. W. (1975) Biochemistry 14, 3220-3224.
41. Giard, J. C., Hartke, A., Flahaut, S., Boutibonnes, P., and Auffray, Y. (1997) Res. Microbiol. 148, 27-35.