Ca2+ signal blockers can inhibit M/A transition in mammalian cells by interfering with the spindle checkpoint

Biochemical and Biophysical Research Communications

Volumn 306, Issue 3, 2003, Pages 737-745

  Xu, Naihan ^a   Luo, Kathy Q ^a   Chang, Donald C ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

BAPTA AM; Calcium; Cyclin B; Metaphase anaphase transition; Microtubule; Mitotic spindle; Securin

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CYCLIN B; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GREEN FLUORESCENT PROTEIN; HEPARIN; TUBULIN; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; ANAPHASE-PROMOTING COMPLEX; CALCIUM; CHELATING AGENT; DRUG DERIVATIVE; EGTAZIC ACID; HYBRID PROTEIN; LIGASE; PHOTOPROTEIN; PITUITARY TUMOR TRANSFORMING PROTEINS; PITUITARY TUMOR-TRANSFORMING PROTEINS; TUMOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANAPHASE; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CARCINOMA CELL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE FUSION; HELA CELL; HUMAN; HUMAN CELL; IMAGING; KIDNEY CELL; MAMMAL CELL; METAPHASE; MITOSIS; MITOSIS INHIBITION; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; UTERINE CERVIX CARCINOMA; ANIMAL; CELL LINE; GENETICS; METABOLISM; PHYSIOLOGY;

MAMMALIA;

ANAPHASE; ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; CHELATING AGENTS; CYCLIN B; EGTAZIC ACID; HELA CELLS; HUMANS; LIGASES; LUMINESCENT PROTEINS; METAPHASE; MITOTIC SPINDLE APPARATUS; NEOPLASM PROTEINS; RECOMBINANT FUSION PROTEINS; TUBULIN; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

EID: 0043133462     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01061-1     Document Type: Article

References (50)

1. Poenie M., Alderton J., Tsien R.Y., Steinhardt R.A. Changes of free calcium levels with stages of the cell division cycle. Nature. 315:1985;147-149.
2. Ratan R.R., Shelanski M.L., Maxfield F.R. Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proc. Natl. Acad. Sci. USA. 83:1986;5136-5140.
3. Tombes R.M., Borisy G.G. Intracellular free calcium and mitosis in mammalian cells: anaphase onset is calcium modulated, but is not triggered by a brief transient. J. Cell Biol. 109:1989;627-636.
4. Hepler P.K. The role of calcium in cell division. Cell Calcium. 16:1994;322-330.
5. Means A.R. Calcium, calmodulin and cell cycle regulation. FEBS Lett. 347:1994;1-4.
6. Whitaker M. Regulation of the cell division cycle by inositol trisphosphate and the calcium signaling pathway. Adv. Second Messenger Phosphoprotein Res. 30:1995;299-310.
7. Muto A., Kume S., Inoue T., Okano H., Mikoshiba K. Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin. J. Cell Biol. 135:1996;181-190.
8. Chang D.C., Meng C. A localized elevation of cytosolic free calcium is associated with cytokinesis in the zebrafish embryo. J. Cell Biol. 131:1995;1539-1545.
9. Jaffe L.F. Sources of calcium in egg activation: a review and hypothesis. Dev. Biol. 99:1983;265-276.
10. Berridge M.J. Inositol trisphosphate and calcium signalling. Nature. 361:1993;315-325.
11. Watanabe N., Hunt T., Ikawa Y., Sagata N. Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs. Nature. 352:1991;247-248.
12. Weber M., Kubiak J.Z., Arlinghaus R.B., Pines J., Maro B. c-mos proto-oncogene product is partly degraded after release from meiotic arrest and persists during interphase in mouse zygotes. Dev. Biol. 148:1991;393-397.
13. Lorca T., Galas S., Fesquet D., Devault A., Cavadore J.C., Doree M. Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+) -calmodulin dependent event. EMBO J. 10:1991;2087-2093.
14. 2+ is involved through type II calmodulin-dependent protein kinase in cyclin degradation and exit from metaphase. Biochim. Biophys. Acta. 1223:1994;325-332.
15. Izant J.G. The role of calcium ions during mitosis. Calcium participates in the anaphase trigger. Chromosoma. 88:1983;1-10.
16. Poenie M., Alderton J., Steinhardt R., Tsien R. Calcium rises abruptly and briefly throughout the cell at the onset of anaphase. Science. 233:1986;886-889.
17. Ratan R.R., Maxfield F.R., Shelanski M.L. Long-lasting and rapid calcium changes during mitosis. J. Cell Biol. 107:1988;993-999.
18. 2+ in mitotic progression of Swiss 3T3 fibroblasts. J. Cell Biol. 111:1990;183-196.
19. Chang D.C. Experimental strategies in efficient transfection of mammalian cells. Eelectroporation. Methods Mol. Biol. 62:1997;307-318.
20. Chang D.C., Gao P.Q., Maxwell B.L. High efficiency gene transfection by electroporation using a radio-frequency electric field. Biochim. Biophys. Acta. 1092:1991;153-160.
21. Pu Y., Chang D.C. Cytosolic Ca(2+) signal is involved in regulating UV-induced apoptosis in HeLa cells. Biochem. Biophys. Res. Commun. 282:2001;84-89.
22. Speksnijder J.E., Miller A.L., Weisenseel M.H., Chen T.H., Jaffe L.F. Calcium buffer injections block fucoid egg development by facilitating calcium diffusion. Proc. Natl. Acad. Sci. USA. 86:1989;6607-6611.
23. Morgan D.O. Regulation of the APC and the exit from mitosis. Nat. Cell Biol. 1:1999;E47-53.
24. Visintin R., Prinz S., Amon A. CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science. 278:1997;460-463.
25. Ciosk R., Zachariae W., Michaelis C., Shevchenko A., Mann M., Nasmyth K. An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell. 93:1998;1067-1076.
26. Zachariae W. Progression into and out of mitosis. Curr. Opin. Cell Biol. 11:1999;708-716.
27. Uhlmann F., Lottspeich F., Nasmyth K. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature. 400:1999;37-42.
28. Waizenegger I.C., Hauf S., Meinke A., Peters J.M. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell. 103:2000;399-410.
29. Hershko A., Ganoth D., Sudakin V., Dahan A., Cohen L.H., Luca F.C., Ruderman J.V., Eytan E. Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2. J. Biol. Chem. 269:1994;4940-4946.
30. King R.W., Peters J.M., Tugendreich S., Rolfe M., Hieter P., Kirschner M.W. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell. 81:1995;279-288.
31. Glotzer M., Murray A.W., Kirschner M.W. Cyclin is degraded by the ubiquitin pathway. Nature. 349:1991;132-138.
32. Fang G., Yu H., Kirschner M.W. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev. 12:1998;1871-1883.
33. Hwang L.H., Lau L.F., Smith D.L., Mistrot C.A., Hardwick K.G., Hwang E.S., Amon A., Murray A.W. Budding yeast Cdc20: a target of the spindle checkpoint. Science. 279:1998;1041-1044.
34. Kim S.H., Lin D.P., Matsumoto S., Kitazono A., Matsumoto T. Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint. Science. 279:1998;1045-1047.
35. Wassmann K., Benezra R. Mad2 transiently associates with an APC/p55Cdc complex during mitosis. Proc. Natl. Acad. Sci. USA. 95:1998;11193-11198.
36. Chen R.H., Shevchenko A., Mann M., Murray A.W. Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores. J. Cell Biol. 143:1998;283-295.
37. Gorbsky G.J., Chen R.H., Murray A.W. Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase. J. Cell Biol. 141:1998;1193-1205.
38. Waters J.C., Chen R.H., Murray A.W., Gorbsky G.J., Salmon E.D., Nicklas R.B. Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis. Curr. Biol. 9:1999;649-652.
39. Fang G., Yu H., Kirschner M.W. Control of mitotic transitions by the anaphase-promoting complex. Philos. Trans. R. Soc., Lond. B Biol. Sci. 354:1999;1583-1590.
40. Doutheil J., Gissel C., Oschlies U., Hossmann K.A., Paschen W. Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis. Brain Res. 775:1997;43-51.
41. Paschen W., Hotop S., Aufenberg C. Loading neurons with BAPTA-AM activates xbp1 processing indicative of induction of endoplasmic reticulum stress. Cell Calcium. 33:2003;83-89.
42. Groigno L., Whitaker M. An anaphase calcium signal controls chromosome disjunction in early sea urchin embryos. Cell. 92:1998;193-204.
43. Lorca T., Cruzalegui F.H., Fesquet D., Cavadore J.C., Mery J., Means A., Doree M. Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs. Nature. 366:1993;270-273.
44. Morin N., Abrieu A., Lorca T., Martin F., Doree M. The proteolysis-dependent metaphase to anaphase transition: calcium/calmodulin- dependent protein kinase II mediates onset of anaphase in extracts prepared from unfertilized Xenopus eggs. EMBO J. 13:1994;4343-4352.
45. Whitaker M. Cell cycle. Sharper than a needle. Nature. 366:1993;211-212.
46. Pozzan T., Rizzuto R., Volpe P., Meldolesi J. Molecular and cellular physiology of intracellular calcium stores. Physiol. Rev. 74:1994;595-636.
47. Marcum J.M., Dedman J.R., Brinkley B.R., Means A.R. Control of microtubule assembly-disassembly by calcium-dependent regulator protein. Proc. Natl. Acad. Sci. USA. 75:1978;3771-3775.
48. Salmon E.D., Segall R.R. Calcium-labile mitotic spindles isolated from sea urchin eggs (Lytechinus variegatus). J. Cell Biol. 86:1980;355-365. dinsmore J.H., Sloboda R.D. Calcium and calmodulin-dependent phosphorylation of a 62-kDa protein induces microtubule depolymerization in sea urchin mitotic apparatuses. Cell. 53:1988;769-780.
49. Dinsmore J.H., Sloboda R.D. Calcium and calmodulin-dependent phosphorylation of a 62-kDa protein induces microtubule depolymerization in sea urchin mitotic apparatuses. Cell. 53:1988;769-780.
50. Descombes P., Nigg E.A. The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J. 17:1998;1328-1335.