Biochemical association of CD45 with the T cell receptor complex: Regulation by CD45 isoform and during T cell activation

Immunity

Volumn 10, Issue 6, 1999, Pages 701-711

  Leitenberg, David ^a   Boutin, Yvan ^a   Lu, Dan Dan ^a   Bottomly, Kim ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0033151580     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80069-2     Document Type: Article

References (42)

1. Akbar, A.M., Terry, L., Timms, A., Beverley, P.C.L., and Janossy, G. (1988). Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J. Immunol. 140, 2171-2178.
2. Bottomly, K., Luqman, M., Greenbaum, L., Carding, S., West, J., Pasqualini, T., and Murphy, D.B. (1989). A monoclonal antibody to murine CD45R distinguishes CD4T cell populations that produce different lymphokines. Eur. J. Immunol. 19, 617-623.
3. Boutin, Y., Leitenberg, D., Tao, X., and Bottomly, K. (1997). Distinct biochemical signals characterize agonist and altered peptide ligand-induced differentiation of naive CD4 T cells into Th1 and Th2 subsets. J. Immunol. 159, 5802-5809.
4. Burns, C.M., Sakaguchi, K., Appella, E., and Ashwell, J.D. (1994). CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases. J. Biol. Chem. 269, 13594-13600.
5. Collins, T., and Burakoff, S. (1993). Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation. Proc. Natl. Acad. Sci. USA 90, 11885-11889.
6. D'Oro, U., Sakaguchi, K., Appella, E., and Ashwell, J.D. (1996). Mutational analysis of lck in CD45-negative T cells: Dominant role of tyrosine 394 phosphorylation in kinase activity. Mol. Cell. Biol. 16, 4996-5003.
7. Duplay, P., Alcover, A., Fargeas, C., Sekaly, R.P., and Branton, P.E. (1996). An activated epidermal growth factor receptor/lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line. J. Biol. Chem. 271, 17896-17902.
8. Furukawa, T., Itoh, M., Krueger, N.X., Streuli, M., and Saito, H. (1994). Specific interaction of the CD45 protein tyrosine phosphatase with tyrosine-phosphorylated CD3 ζζ chain. Proc. Natl. Acad. Sci. USA 91, 10928-10929.
9. lck protein tyrosine kinase: A functional complex crucial in T cell signal transduction. Int. Immunol. 4, 1325-1330.
10. Hathcock, K.S., Laszlo, G., Dickler, H.B., Sharrow, S.O., Johnson, P., Trowbridge, I.S., and Hodes, R.J. (1992). Expression of variable exon A-,B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J. Immunol. 148, 19-28.
11. Kaye, J., Porcelli, S., Tite, J., Jones, B., and Janeway, C.A. (1983). Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen presenting cells in the activation of T cells. J. Exp. Med. 158, 836-856.
12. + T cells in transgenic mice express a class II MHC restricted antigen receptor. Nature 341, 746-749.
13. Koretzky, G.A., Kohmetscher, M., and Ross, S. (1993). CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line. J. Biol. Chem. 268, 8958-8964.
14. Lee, W.T., Yin, X.M., and Vitetta, E.S. (1990). Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells. J. Immunol. 144, 3288-3295.
15. Lefrancois, L., and Goodman, T. (1987). Developmental sequence of T200 antigen modifications in murine T cells. J. Immunol. 139, 3718-3724.
16. Leitenberg, D., Novak, T., Farber, D., Smith, B., and Bottomly, K. (1996). The extracellular domain of CD45 controls association with the CD4 T cell receptor complex and the response to antigen-specific stimulation. J. Exp. Med. 183, 249-259.
17. Leitenberg, D., Boutin, Y., Constant, S., and Bottomly, K. (1998). CD4 regulation of T cell receptor signaling and T cell differentiation following stimulation with peptides of different affinites for the T cell receptor. J. Immunol. 161, 1194-1203.
18. Luqman, M., Johnson, P., Trowbridge, I.S., and Bottomly, K. (1991). Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 cloned lines. Eur. J. Immunol. 21, 17-22.
19. Madrenas, J., Chau, L.A., Smith, J., Bluestone, J.A., and Germain, R.N. (1997). The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. J. Exp. Med. 185, 219-229.
20. Matsuda, A., Motoya, S., Kimura, S., McInnis, R., Maizel, A.L., and Takeda, A. (1998). Disruption of lymphocyte function and signaling in CD45-associated protein-null mice. J. Exp. Med. 187,1863-1870.
21. McCall, M.N., Shotton, D.M., and Barclay, A.N. (1992). Expression of soluble isoforms of rat CD45. Analysis by electron microscopy and use in epitope mapping of anti-CD45R monoclonal antibodies. Immunology 76, 310-317.
22. McFarland, E.D., and Thomas, M.L. (1995). CD45 protein-tyrosine phosphatase associates with the WW domain-containing protein, CD45AP, through the transmembrane region. J. Biol. Chem. 270, 28103-28107.
23. McFarland, E.D.C., Hurley, T.M., Pingel, J.T., Sefton, B.M., Shaw, A., and Thomas, M.L. (1993). Correlation between src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. Proc. Natl. Acad. Sci. USA 90, 1402-1406.
24. McKenney, D.W., Onodera, H., Gorman, L., Mimura, T., and Rothstein, D.M. (1995). Distinct isoforms of CD45 protein tyrosine phosphatase differentially regulate interleukin 2 secretion and activation signal pathways involving vav in T cells. J. Biol. Chem. 270, 24949-24954.
25. Montixi, C., Langlet, C., Bernard, A.-M., Thimonier, J., Dubois, C., Wurbel, M.-A., Chauven, J.-P., Pierres, M., and He, H.-T. (1998). Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J. 17, 5334-5348.
26. lck by the CD45 phosphotyrosine phosphatase. Proc. Natl. Acad. Sci. USA 86,6302-6306.
27. fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase. Eur. J. Immunol. 22, 1173-1178.
28. ZAP tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase. Eur. J. Immunol. 25, 942-946.
29. Novak, T., Farber, D., Cheol Hong, S., Johnson, P., and Bottomly, K. (1994). Isoforms of the transmembrane tyrosine phosphatase CD45 differentially affect T cell recognition. Immunity 1, 109-119.
30. Ostergaard, H.L., Shackelford, D.A., Hurley, T.R., Johnson, P., Hyman, R., Sefton, B.M., and Trowbridge, I.S. (1989). Expression of CD45 alters phosphorylation of the lck-encoded tyrosine kinase in murine lymphoma T-cell lines. Proc. Natl. Acad. Sci. USA 86, 8959-8963.
31. Rodgers, W., and Rose, J.K. (1996). Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains. J. Cell. Biol. 135, 1515-1523.
32. Rogers, P.R., Pilapil, S., Hayakawa, K., Romain, P.L., and Parker, D.C. (1992). CD45 Alternative exon expression in murine and human CD4+ T cell subsets. J. Immunol. 148, 4054-4065.
33. Ross, S.E., Schraven, B., Goldman, F.D., Crabtree, J., and Koretzky, G.A. (1994). The association between CD45 and lck does not require CD4 or CD8 and is independent of T cell receptor stimulation. Biochem. Biophys. Res. Commun. 198, 88-96.
34. lck, and pp32, a possible common substrate. Eur. J. Immunol. 21, 2469-2477.
35. Shaw, A.S., and Dustin, M.L. (1997). Making the T cell receptor go the distance: A topological view of T cell activation. Immunity 6, 361-369.
36. Sieh, M., Bolen, J.B., and Weiss, A. (1993). CD45 specifically modulates binding of lck to a phosphopeptide encompassing the negative regulatory tyrosine of lck. EMBO J. 12, 315-321.
37. Sperling, A., Sedy, J., Manjunath, N., Kupfer, A., Ardman, B., and Burkhardt, J. (1998). TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site. J. Immunol. 161, 6459-6462.
38. Tao, X., Grant, C., Constant, S., and Bottomly, K. (1997). Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding. J. Immunol. 158, 4237-4244.
39. Trowbridge, I.S., and Thomas, M.L. (1994). CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12, 85-116.
40. Xavier, R., Brennan, T., Li, Q., McCormack, C., and Seed, B. (1998). Membrane compartmentation is required for efficient T cell activation. Immunity 8, 723-732.
41. Xu, H., and Littman, D.R. (1993). A kinase-independent function of lck in potentiating antigen-specific T cell activation. Cell 74, 633-644.
42. Zhang, W., Trible, R.P., and Samelson, L.E. (1998). LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 9, 239-246.