Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization

Protein Science

Volumn 12, Issue 9, 2003, Pages 1960-1970

  Walsh, Scott T R ^a   Jevitts, Liz M ^a   Sylvester, Juliesta E ^a   Kossiakoff, Anthony A ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Alanine scanning; Binding energetics; Extracellular domain of human growth hormone; Human growth hormone; Regulatory step; Surface plasmon resonance

Indexed keywords

ALANINE; GROWTH HORMONE; GROWTH HORMONE RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING KINETICS; BINDING SITE; CELL SURFACE; DIMERIZATION; ENERGY TRANSFER; EXTRACELLULAR SPACE; HORMONAL REGULATION; HUMAN; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE;

ALANINE; BINDING SITES; DIMERIZATION; EPITOPES; HUMAN GROWTH HORMONE; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE; TIME FACTORS;

EID: 0043012982     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.03133903     Document Type: Article

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