A novel peroxisome proliferator-activated gamma (PPARγ) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential

Metabolism: Clinical and Experimental

Volumn 52, Issue 8, 2003, Pages 1012-1018

  Dey, Debendranath ^a   Medicherla, Satya ^a   Neogi, Partha ^a   Gowri, Maya ^a   Cheng, Jin ^a   Gross, Coleman ^a   Sharma, Somesh D ^a   Reaven, Gerald M ^a   Nag, Bishwajit ^a  

^a Calyx Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; CLX 0921; CYCLOHEXIMIDE; GLUCOSE; GLYCOGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIG INSULIN; PIOGLITAZONE; ROSIGLITAZONE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERGLYCEMIC ACTIVITY; ARTICLE; BIOEQUIVALENCE; CELL STRAIN 3T3; CELL STRAIN HEPG2; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIPOGENESIS; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

EID: 0042888577     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(03)00152-5     Document Type: Article

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